TSN and GIT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TSN	GIT2
Gene Name		translin	G protein-coupled receptor kinase interacting ArfGAP 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleoplasm Focal Adhesion
	Molecular Function	DNA Binding Single-stranded DNA Binding MRNA Binding Endoribonuclease Activity Protein Binding Protein Complex Binding Sequence-specific DNA Binding	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding
	Biological Process	DNA Recombination Gene Expression RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Behavioral Response To Pain
Pathways		Regulatory RNA pathways Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Erectile dysfunction and prostate cancer treatment ( 20932654)	Metabolic syndrome ( 20694148) Metabolite levels (MHPG) ( 23319000)
Protein-Protein Interactions		4 interactors: GIT2 PPP1R15A TSNAX ZBTB18	44 interactors: ACTG1 ACTN1 ADRBK1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		7247	9815
HPRD ID		08993	09779
Ensembl ID		ENSG00000211460	ENSG00000139436
Uniprot IDs		B3KRM8 Q15631	F8VXI9 Q14161 Q6FI58
PDB IDs		1J1J 3PJA 3QB5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Translation In Response To Stress Positive Regulation Of Peptidyl-serine Dephosphorylation Negative Regulation Of Protein Dephosphorylation Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Translational Initiation In Response To Stress Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Translational Initiation Regulation Of Translation In Response To Stress	Regulation Of Apoptotic Process Regulation Of Cell Death Ephrin Receptor Signaling Pathway Innate Immune Response Response To External Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Apoptotic Process Regulation Of Signaling Programmed Cell Death Regulation Of Signal Transduction Immune System Process Immune Response Regulation Of Immune System Process Cell Death Regulation Of Metabolic Process Death Positive Regulation Of Immune Response Defense Response Signal Transduction Regulation Of Immune Response Immune Response-regulating Signaling Pathway Adherens Junction Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Immune System Process Focal Adhesion Assembly Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Regulation Of Phosphorus Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-cell Junction Organization Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Signaling Regulation Of Kinase Activity Cellular Component Assembly Cell Communication Regulation Of Phosphorylation Adherens Junction Assembly Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Cell Development Cell-substrate Junction Assembly Activation Of MAPK Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Stress Activation Of Innate Immune Response Cell Surface Receptor Signaling Pathway
Tagcloud ?		bax bcl cardiomyocyte circumferential commencing cvf d18 diameter distilled eosin gieson hematoxylin hypertensive iia immunohistological lvh lvmi pcva perivascular pvca s18 s8 sacrificed sbp shrs spontaneously tanshinone van ventricular	ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Difference) ?		bax bcl cardiomyocyte circumferential commencing cvf d18 diameter distilled eosin gieson hematoxylin hypertensive iia immunohistological lvh lvmi pcva perivascular pvca s18 s8 sacrificed sbp shrs spontaneously tanshinone van ventricular	ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Intersection) ?