GIT2 and KCTD5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		GIT2	KCTD5
Gene Name		G protein-coupled receptor kinase interacting ArfGAP 2	potassium channel tetramerization domain containing 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Focal Adhesion	Nucleus Cytosol
	Molecular Function	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding	Protein Binding Protein Complex Binding
	Biological Process	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Behavioral Response To Pain	Viral Process Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Metabolic syndrome ( 20694148) Metabolite levels (MHPG) ( 23319000)
Protein-Protein Interactions		44 interactors: ACTG1 ACTN1 ADRBK1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG	8 interactors: CD1A CUL3 EP300 GIT2 GORASP2 NEK6 NXF1 PRKAB2
Entrez ID		9815	54442
HPRD ID		09779	13768
Ensembl ID		ENSG00000139436	ENSG00000167977
Uniprot IDs		F8VXI9 Q14161 Q6FI58	Q9NXV2
PDB IDs			3DRX 3DRY 3DRZ
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Cell Death Ephrin Receptor Signaling Pathway Innate Immune Response Response To External Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Apoptotic Process Regulation Of Signaling Programmed Cell Death Regulation Of Signal Transduction Immune System Process Immune Response Regulation Of Immune System Process Cell Death Regulation Of Metabolic Process Death Positive Regulation Of Immune Response Defense Response Signal Transduction Regulation Of Immune Response Immune Response-regulating Signaling Pathway Adherens Junction Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Immune System Process Focal Adhesion Assembly Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Regulation Of Phosphorus Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-cell Junction Organization Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Signaling Regulation Of Kinase Activity Cellular Component Assembly Cell Communication Regulation Of Phosphorylation Adherens Junction Assembly Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Cell Development Cell-substrate Junction Assembly Activation Of MAPK Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Stress Activation Of Innate Immune Response Cell Surface Receptor Signaling Pathway	Cell Cycle Mitotic Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Cell Cycle Cell Cycle Process Histone H2B Acetylation Regulation Of Mitotic Nuclear Division Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process N-terminal Peptidyl-lysine Acetylation Trophectodermal Cellular Morphogenesis Cell Cycle Arrest Mitotic Cell Cycle Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Regulation Of Tubulin Deacetylation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase By Cyclin Degradation Organelle Organization Intrinsic Apoptotic Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Membrane Organization Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cellular Protein Metabolic Process Chromosome Segregation Positive Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Cell Cycle Phase Transition Carnitine Shuttle Regulation Of Cell Division Poly(A)+ MRNA Export From Nucleus Mitotic Cell Cycle Phase Transition Apoptotic Process Cell Cycle Phase Transition Positive Regulation By Host Of Viral Transcription Programmed Cell Death Regulation Of Protein Metabolic Process Carnitine Transmembrane Transport N-terminal Protein Amino Acid Acetylation Carnitine Transport Cell Death Death Embryonic Cleavage Mitotic Nuclear Division Stress Fiber Assembly Positive Regulation Of Chromosome Segregation Apoptotic Signaling Pathway Quaternary Ammonium Group Transport COPII Vesicle Coating Regulation Of Protein Catabolic Process Regulation Of Androgen Receptor Signaling Pathway
Tagcloud ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Difference) ?		ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Intersection) ?