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GIT2 and SAFB2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
GIT2
SAFB2
Gene Name
G protein-coupled receptor kinase interacting ArfGAP 2
scaffold attachment factor B2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Focal Adhesion
Nucleoplasm
Cytoplasm
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
ARF GTPase Activator Activity
Zinc Ion Binding
Nucleotide Binding
DNA Binding
Protein Binding
Identical Protein Binding
Poly(A) RNA Binding
Biological Process
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of ARF GTPase Activity
Positive Regulation Of GTPase Activity
Behavioral Response To Pain
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Metabolic syndrome (
20694148
)
Metabolite levels (MHPG) (
23319000
)
vWF and FVIII levels (
21810271
)
Protein-Protein Interactions
44 interactors:
ACTG1
ACTN1
ADRBK1
ARHGEF7
ATF5
C4BPA
CALCOCO2
CORO1A
E2F2
EDC4
GCH1
GIT1
GUSB
HGD
HNRNPUL1
IKBKG
KCTD5
KRT18
LMNB1
MVP
NFKBIB
NME2
PAK1
PAK3
PCLO
POLR1B
PROX1
PXN
QPRT
RCVRN
RUFY1
RUSC2
SAFB2
SH3GLB2
SMAD3
SPOP
TGFB1I1
TNFAIP3
TNIP1
TRAF1
TSN
UBQLN1
USHBP1
YWHAG
8 interactors:
CHGB
ESR1
FNTA
FUS
GIT2
SAFB
SORBS3
ZSCAN18
Entrez ID
9815
9667
HPRD ID
09779
06424
Ensembl ID
ENSG00000139436
ENSG00000130254
Uniprot IDs
F8VXI9
Q14161
Q6FI58
Q14151
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Apoptotic Process
Regulation Of Cell Death
Ephrin Receptor Signaling Pathway
Innate Immune Response
Response To External Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Response To Stimulus
Apoptotic Process
Regulation Of Signaling
Programmed Cell Death
Regulation Of Signal Transduction
Immune System Process
Immune Response
Regulation Of Immune System Process
Cell Death
Regulation Of Metabolic Process
Death
Positive Regulation Of Immune Response
Defense Response
Signal Transduction
Regulation Of Immune Response
Immune Response-regulating Signaling Pathway
Adherens Junction Organization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Immune System Process
Focal Adhesion Assembly
Positive Regulation Of Metabolic Process
Regulation Of Catalytic Activity
Regulation Of Phosphorus Metabolic Process
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell-cell Junction Organization
Regulation Of Protein Kinase Activity
Positive Regulation Of Catalytic Activity
Signaling
Regulation Of Kinase Activity
Cellular Component Assembly
Cell Communication
Regulation Of Phosphorylation
Adherens Junction Assembly
Regulation Of Protein Phosphorylation
Regulation Of Cellular Component Organization
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Regulation Of Cell Development
Cell-substrate Junction Assembly
Activation Of MAPK Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Response To Stress
Activation Of Innate Immune Response
Cell Surface Receptor Signaling Pathway
Intracellular Estrogen Receptor Signaling Pathway
Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Tubulin Deacetylation
Prostate Epithelial Cord Elongation
Positive Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Protein Farnesylation
Hormone Metabolic Process
Regulation Of Tubulin Deacetylation
Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Intracellular Receptor Signaling Pathway
Positive Regulation Of Deacetylase Activity
Branch Elongation Involved In Mammary Gland Duct Branching
Antral Ovarian Follicle Growth
Neurotransmitter Receptor Metabolic Process
Protein Geranylgeranylation
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Mammary Gland Branching Involved In Pregnancy
Regulation Of Hormone Levels
Positive Regulation Of Hydrolase Activity
Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis
Positive Regulation Of Cellular Metabolic Process
Vagina Development
Uterus Development
Protein Prenylation
Regulation Of Signal Transduction
Regulation Of Metabolic Process
Positive Regulation Of Nitric-oxide Synthase Activity
Cellular Response To Estradiol Stimulus
Prostate Gland Growth
Branching Involved In Prostate Gland Morphogenesis
Mammary Gland Epithelial Cell Proliferation
Female Genitalia Development
Behavioral Response To Pain
Regulation Of Signaling
Positive Regulation Of Monooxygenase Activity
Branch Elongation Of An Epithelium
Positive Regulation Of Catalytic Activity
Positive Regulation Of Protein Deacetylation
Regulation Of Rhodopsin Mediated Signaling Pathway
Cellular Response To Estrogen Stimulus
RNA Metabolic Process
Growth
Tagcloud
?
ancient
autophosphorylation
coordinates
deregulated
dimerization
exchange
gef
git1
gtpase
guanine
hippo
hpo
interacting
mammals
melanogaster
metazoan
oligomeric
originally
pak
pix
polarity
proteomics
rho
rtgef
salvador
scaffold
sterile
undefined
Tagcloud (Difference)
?
ancient
autophosphorylation
coordinates
deregulated
dimerization
exchange
gef
git1
gtpase
guanine
hippo
hpo
interacting
mammals
melanogaster
metazoan
oligomeric
originally
pak
pix
polarity
proteomics
rho
rtgef
salvador
scaffold
sterile
undefined
Tagcloud (Intersection)
?