TSN and ZBTB18

Number of citations of the paper that reports this interaction (PubMedID 9756912)
0

Data Source:
BioGRID (two hybrid)

		TSN	ZBTB18
Description		translin	zinc finger and BTB domain containing 18
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GO Annotations	Cellular Component	Male Germ Cell Nucleus Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Endoribonuclease Complex	Heterochromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Nucleic Acid Binding DNA Binding Single-stranded DNA Binding RNA Binding MRNA Binding Nuclease Activity Endonuclease Activity Protein Binding Hydrolase Activity Identical Protein Binding Sequence-specific DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	RNA Metabolic Process SiRNA Processing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Disease progression in age-related macular degeneration ( 29346644) Erectile dysfunction and prostate cancer treatment ( 20932654) Food antigen IgG levels ( 24962563) Hepcidin/ferritin ratio ( 27846281) Major depressive disorder x sex interaction ( 34099189) Paclitaxel disposition in epithelial ovarian cancer ( 29367611) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction ( 34099189) Smoking status (ever vs never smokers) ( 30643258) Waist circumference ( 34074324)	Adventurousness ( 30643258) General risk tolerance (MTAG) ( 30643258) Mercury levels ( 26025379)
Interacting Genes		17 interacting genes: CEBPA DVL3 FXR1 GIT2 GORASP2 HOXC4 LNX1 MORF4L2 NTAQ1 PICK1 PPP1R15A SDCBP SIN3A TSNAX UBE2I UBE2K ZBTB18	9 interacting genes: DNMT3A DNMT3B LINC02774 MYLIP PAK1 PIK3R3 POMGNT1 TSN ZBTB2
Entrez ID		7247	10472
HPRD ID		08993	12231
Ensembl ID		ENSG00000211460	ENSG00000179456
Uniprot IDs		B3KRM8 Q15631	Q99592
PDB IDs		1J1J 3PJA 3QB5 4WYV	8P2P
Enriched GO Terms of Interacting Partners?			DNA (cytosine-5-)-methyltransferase Activity Catalytic Complex DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates Fc Receptor Signaling Pathway Regulation Of B Cell Antigen Processing And Presentation Cerebellum Development Fc-gamma Receptor Signaling Pathway Immune Complex Clearance By Monocytes And Macrophages Negative Regulation Of Type I Hypersensitivity Negative Regulation Of Antibody-dependent Cellular Cytotoxicity Protein-cysteine Methyltransferase Activity Transferase Activity DNA-methyltransferase Activity Regulation Of Immune Complex Clearance By Monocytes And Macrophages Low-affinity IgG Receptor Activity Negative Regulation Of Cytotoxic T Cell Degranulation Follicular Dendritic Cell Activation Immune Complex Clearance Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,3-N-acetylglucosaminyltransferase Activity
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