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GIT2 and LMNB1
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
GIT2
LMNB1
Description
GIT ArfGAP 2
lamin B1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Focal Adhesion
Synapse
Presynapse
Nucleus
Nuclear Envelope
Nuclear Inner Membrane
Lamin Filament
Nuclear Lamina
Nucleoplasm
Intermediate Filament
Membrane
Nuclear Matrix
Nuclear Membrane
Nuclear Periphery
Molecular Function
GTPase Activator Activity
Protein Binding
Zinc Ion Binding
Small GTPase Binding
Metal Ion Binding
Double-stranded DNA Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Phospholipase Binding
Structural Constituent Of Nuclear Lamina
Sequence-specific Double-stranded DNA Binding
Biological Process
Brain Development
Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of ARF Protein Signal Transduction
Synaptic Vesicle Recycling
Nuclear Envelope Organization
Cytoskeleton Organization
Nuclear Migration
Heterochromatin Formation
Nuclear Pore Localization
Protein Localization To Nuclear Envelope
Pathways
CDC42 GTPase cycle
RAC1 GTPase cycle
RAC2 GTPase cycle
RHOQ GTPase cycle
RHOJ GTPase cycle
RHOU GTPase cycle
RAC3 GTPase cycle
RHOV GTPase cycle
Meiotic synapsis
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Nuclear Envelope Breakdown
Initiation of Nuclear Envelope (NE) Reformation
Breakdown of the nuclear lamina
Depolymerization of the Nuclear Lamina
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
RHOD GTPase cycle
RHOF GTPase cycle
Drugs
Diseases
GWAS
Bipolar disorder (
31043756
)
Disturbances of the gamma-frequency band of electroencephalography measures in schizophrenia (
28922980
)
Metabolic syndrome (
20694148
)
Metabolite levels (
23823483
)
Metabolite levels (MHPG) (
23319000
)
Blood protein levels (
30072576
)
Body fat percentage (
31752434
)
Parkinson's disease (motor and cognition) (
22658654
)
Interacting Genes
47 interacting genes:
ACTG1
ACTN1
ARHGEF7
ATF5
C4BPA
CALCOCO2
CDC42
CORO1A
E2F2
EDC4
GCH1
GET4
GIT1
GRK2
GUSB
HGD
HNRNPUL1
IKBKG
KCTD5
KRT18
LAMTOR5
LMNB1
MVP
NFKBIB
NME2
PAK1
PAK3
PCLO
POLR1B
PROX1
PXN
QPRT
RCVRN
RUFY1
RUSC2
SAFB2
SH3GLB2
SMAD3
SPOP
TGFB1I1
TNFAIP3
TNIP1
TRAF1
TSN
UBQLN1
USHBP1
YWHAG
42 interacting genes:
ABCG8
ATF4
CASP3
CASP6
CCDC88B
CDK1
CENPH
DMAP1
FAM169A
GABARAP
GIT2
GZMA
GZMB
KPNA5
KPNA6
LBR
LMNA
M1AP
MAP1LC3A
MAP1LC3C
MBIP
MELK
PIAS2
PIH1D2
PLEC
PPP1R13B
PRKCA
PRKCB
PRKCD
PRPH
PTEN
RNF123
SERPINA3
SNAPIN
SRPK2
SUMO4
TMPO
TOR1AIP1
TP53BP2
UBE2I
URB2
YWHAQ
Entrez ID
9815
4001
HPRD ID
09779
01036
Ensembl ID
ENSG00000139436
ENSG00000113368
Uniprot IDs
F8VXI9
F8W822
Q14161
Q6FI58
B4DZT3
P20700
PDB IDs
2KPW
3JT0
3TYY
3UMN
5BNW
5VVX
7DTG
Enriched GO Terms of Interacting Partners
?
Identical Protein Binding
Cytosol
Regulation Of Supramolecular Fiber Organization
Cytoplasm
Focal Adhesion
Regulation Of Cytoskeleton Organization
Regulation Of Actin Cytoskeleton Organization
Regulation Of Actin Filament Organization
Regulation Of Stress Fiber Assembly
Positive Regulation Of Supramolecular Fiber Organization
Regulation Of Actin Filament-based Process
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Cytoskeleton Organization
Lamellipodium
Ephrin Receptor Signaling Pathway
Cell-cell Junction
Regulation Of Microtubule Nucleation
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of Actin Filament Bundle Assembly
Cell Junction Organization
Regulation Of Lung Blood Pressure
Actin Cytoskeleton Organization
Regulation Of Signal Transduction
Actin Filament
Cytoskeleton
Gamma-tubulin Binding
Actin Filament-based Process
Response To Type II Interferon
Regulation Of Intracellular Signal Transduction
Ruffle
Positive Regulation Of Microtubule Nucleation
Regulation Of Canonical NF-kappaB Signal Transduction
Postsynapse Organization
Extracellular Exosome
Cytoskeleton Organization
Regulation Of Organelle Organization
Profilin Binding
Signal Transduction
Thioesterase Binding
Neuron Fate Determination
Regulation Of Apoptotic Process
Regulation Of Cell Communication
Regulation Of Signaling
Positive Regulation Of Organelle Organization
Vinculin Binding
Regulation Of Programmed Cell Death
Ameboidal-type Cell Migration
Regulation Of Toll-like Receptor 3 Signaling Pathway
Cell Surface Receptor Signaling Pathway
Immunological Synapse Formation
Intrinsic Apoptotic Signaling Pathway
Apoptotic Signaling Pathway
Cell Death
Apoptotic Process
Programmed Cell Death
Nuclear Membrane Organization
Protein Kinase C Signaling
Cellular Response To Nitrogen Starvation
Intracellular Signal Transduction
Mitotic Nuclear Membrane Disassembly
Membrane Organization
Cytoplasm
Cellular Response To Chemical Stress
Pyroptotic Inflammatory Response
Phosphatidylethanolamine Binding
Nuclear Membrane Disassembly
Nuclear Inner Membrane
Histone H3T6 Kinase Activity
Autophagosome Maturation
Membrane Disassembly
Lamin Binding
Nucleoplasm
Diacylglycerol-dependent Serine/threonine Kinase Activity
Cytosol
Nuclear Envelope
Response To Stress
Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity
Regulation Of Apoptotic Process
Positive Regulation Of Neuron Apoptotic Process
Response To Oxidative Stress
Nucleus
Regulation Of Programmed Cell Death
Intracellular Signaling Cassette
Cellular Response To Staurosporine
SUMO Ligase Complex
Regulation Of Protein Localization To Nucleus
Positive Regulation Of Apoptotic Process
Response To Reactive Oxygen Species
Positive Regulation Of Programmed Cell Death
Nucleus Organization
Response To Hydrogen Peroxide
Protein Maturation
Positive Regulation Of Establishment Of Protein Localization
Positive Regulation Of Protein Import Into Nucleus
Regulation Of Endodeoxyribonuclease Activity
Cardiac Muscle Cell Development
Cellular Response To Oxidative Stress
Cardiac Cell Development
Protein Phosphorylation
Protein Serine Kinase Activity
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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