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TPM3 and TFPT
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid, two hybrid)
HPRD
(two hybrid)
TPM3
TFPT
Gene Name
tropomyosin 3
TCF3 (E2A) fusion partner (in childhood Leukemia)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Stress Fiber
Podosome
Cytosol
Cytoskeleton
Muscle Thin Filament Tropomyosin
Growth Cone
Cortical Cytoskeleton
Filamentous Actin
Cleavage Furrow
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Actin Filament
Ino80 Complex
Nuclear Membrane
Molecular Function
Molecular_function
Actin Binding
DNA Binding
Protein Binding
Protein Kinase Binding
Protein Heterodimerization Activity
Biological Process
Movement Of Cell Or Subcellular Component
Muscle Contraction
Muscle Filament Sliding
DNA Repair
DNA Recombination
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Positive Regulation Of Apoptotic Process
Apoptotic Signaling Pathway
Pathways
Striated Muscle Contraction
Smooth Muscle Contraction
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
41 interactors:
ACTA1
ACTB
BLOC1S6
C1orf216
CCDC102B
CCDC114
CCDC146
CCHCR1
CNN1
FAM9C
FBXO5
HDDC3
HSF2
IFIT3
IKBIP
KCNE1
KIFC3
KXD1
LCA5L
LURAP1
MAD1L1
MAGEA11
NEK2
OIP5
PBX3
S100A2
S100A4
SMAD3
SUMO4
SYCE1
TFPT
THAP1
TLK1
TMOD1
TMOD2
TNNT1
TRAP1
TRIM27
TRIP6
VPS52
WASH3P
23 interactors:
APP
C4orf46
CCDC67
CDCA7L
DYDC1
EAF1
EAF2
ELL
HAUS1
KRT19
LMO2
NOL3
PAWR
PIM1
RALBP1
RPGRIP1
RUNDC3A
SDCCAG3
STK3
TCF3
TFIP11
TPM1
TPM3
Entrez ID
7170
29844
HPRD ID
01840
10266
Ensembl ID
ENSG00000143549
ENSG00000105619
Uniprot IDs
B4DQ80
P06753
Q5VU58
Q5VU63
Q8TCG3
P0C1Z6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Actomyosin Structure Organization
Organelle Organization
Actin Filament-based Process
Regulation Of Organelle Organization
Cellular Component Assembly
Actin-myosin Filament Sliding
Muscle Filament Sliding
Actin Cytoskeleton Organization
Regulation Of Actin Filament-based Process
Cytoskeleton Organization
Actin-mediated Cell Contraction
Regulation Of Cytoskeleton Organization
Actin Filament Organization
Actin Filament-based Movement
Regulation Of Actin Filament Polymerization
Regulation Of Actin Cytoskeleton Organization
Pointed-end Actin Filament Capping
Regulation Of Chromosome Segregation
Regulation Of Actin Polymerization Or Depolymerization
Myofibril Assembly
Regulation Of Actin Filament Length
Cell-cell Junction Organization
Regulation Of Mitotic Cell Cycle
Muscle Contraction
Cell Division
Cell Cycle
Muscle System Process
Organelle Assembly
Negative Regulation Of Protein Catabolic Process
Regulation Of Mitotic Nuclear Division
Cell Development
Movement Of Cell Or Subcellular Component
Mitotic Nuclear Division
Regulation Of Cellular Component Size
Regulation Of Protein Complex Assembly
Regulation Of Cellular Component Organization
Regulation Of Muscle Contraction
Positive Regulation Of Transcription Factor Import Into Nucleus
Striated Muscle Cell Development
Negative Regulation Of Centriole-centriole Cohesion
Positive Regulation Of Transforming Growth Factor Beta3 Production
Inhibition Of APC-Cdc20 Complex Activity
Regulation Of Metaphase Plate Congression
Posterior Compartment Specification
Anterior Compartment Pattern Formation
Negative Regulation Of Cytoskeleton Organization
Regulation Of Mitotic Sister Chromatid Separation
Arp2/3 Complex-mediated Actin Nucleation
Muscle Cell Development
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Metabolic Process
Apoptotic Process
RNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Programmed Cell Death
Regulation Of Metabolic Process
Cell Death
Death
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Gene Expression
Embryo Development
Regulation Of Transcription, DNA-templated
Actin-myosin Filament Sliding
Muscle Filament Sliding
Regulation Of Nucleic Acid-templated Transcription
Embryonic Hemopoiesis
Regulation Of RNA Biosynthetic Process
Cell Differentiation Involved In Embryonic Placenta Development
Regulation Of RNA Metabolic Process
Regulation Of Catalytic Activity
Organelle Assembly
Actin-mediated Cell Contraction
Cellular Component Assembly
In Utero Embryonic Development
Spliceosomal Complex Disassembly
Response To Injury Involved In Regulation Of Muscle Adaptation
Positive Regulation Of Heart Rate By Epinephrine
Sarcomere Organization
Regulation Of B Cell Proliferation
Positive Regulation Of Macromolecule Biosynthetic Process
Actin Filament-based Movement
Positive Regulation Of Catalytic Activity
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process
Positive Regulation Of Cell Cycle
Actin Filament-based Process
Myofibril Assembly
Transcription, DNA-templated
Organ Development
Muscle Cell Differentiation
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis
Collateral Sprouting In Absence Of Injury
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tissue Development
Protein Stabilization
Developmental Process
Tagcloud
?
aacr
accelerated
advancements
ago
approved
developments
discov
encodes
fda
fusions
harboring
next
ntrk1
oncd
oncogene
oncogenic
oncology
originally
precision
rationale
rearrangements
revisit
scientific
throughput
transforming
trk
trka
trkb
trkc
Tagcloud (Difference)
?
aacr
accelerated
advancements
ago
approved
developments
discov
encodes
fda
fusions
harboring
next
ntrk1
oncd
oncogene
oncogenic
oncology
originally
precision
rationale
rearrangements
revisit
scientific
throughput
transforming
trk
trka
trkb
trkc
Tagcloud (Intersection)
?