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TFPT and STK3
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
TFPT
STK3
Gene Name
TCF3 (E2A) fusion partner (in childhood Leukemia)
serine/threonine kinase 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Actin Filament
Ino80 Complex
Nuclear Membrane
Nucleus
Cytoplasm
Cytosol
Molecular Function
DNA Binding
Protein Binding
Protein Kinase Binding
Protein Heterodimerization Activity
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Receptor Signaling Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein Serine/threonine Kinase Activator Activity
Protein Dimerization Activity
Biological Process
DNA Repair
DNA Recombination
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Positive Regulation Of Apoptotic Process
Apoptotic Signaling Pathway
Neural Tube Formation
Endocardium Development
Protein Phosphorylation
Apoptotic Process
Signal Transduction
Central Nervous System Development
Negative Regulation Of Cell Proliferation
Signal Transduction By Phosphorylation
Positive Regulation Of Protein Binding
Hippo Signaling
Intracellular Signal Transduction
Positive Regulation Of Apoptotic Process
Positive Regulation Of Fat Cell Differentiation
Positive Regulation Of JNK Cascade
Negative Regulation Of Organ Growth
Protein Stabilization
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Protein Kinase B Signaling
Primitive Hemopoiesis
Cell Differentiation Involved In Embryonic Placenta Development
Positive Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Canonical Wnt Signaling Pathway
Hepatocyte Apoptotic Process
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Signaling by Hippo
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
23 interactors:
APP
C4orf46
CCDC67
CDCA7L
DYDC1
EAF1
EAF2
ELL
HAUS1
KRT19
LMO2
NOL3
PAWR
PIM1
RALBP1
RPGRIP1
RUNDC3A
SDCCAG3
STK3
TCF3
TFIP11
TPM1
TPM3
33 interactors:
AKT1
CASP3
CNKSR1
CPNE1
DDAH2
EIF4EBP1
FAM9B
GAD1
GBP2
GMCL1
HSPE1
KHSRP
LATS1
LATS2
LRRK2
MBP
MOB4
MPP1
ORM2
PEX19
PHAX
QARS
RAF1
RASSF1
RASSF2
RASSF4
RASSF5
SAV1
SLMAP
SULT2A1
TFPT
TRAF1
ZC3H7A
Entrez ID
29844
6788
HPRD ID
10266
05433
Ensembl ID
ENSG00000105619
ENSG00000104375
Uniprot IDs
P0C1Z6
B3KYA7
Q13188
PDB IDs
4HKD
4L0N
4LG4
4LGD
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Metabolic Process
Apoptotic Process
RNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Programmed Cell Death
Regulation Of Metabolic Process
Cell Death
Death
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Gene Expression
Embryo Development
Regulation Of Transcription, DNA-templated
Actin-myosin Filament Sliding
Muscle Filament Sliding
Regulation Of Nucleic Acid-templated Transcription
Embryonic Hemopoiesis
Regulation Of RNA Biosynthetic Process
Cell Differentiation Involved In Embryonic Placenta Development
Regulation Of RNA Metabolic Process
Regulation Of Catalytic Activity
Organelle Assembly
Actin-mediated Cell Contraction
Cellular Component Assembly
In Utero Embryonic Development
Spliceosomal Complex Disassembly
Response To Injury Involved In Regulation Of Muscle Adaptation
Positive Regulation Of Heart Rate By Epinephrine
Sarcomere Organization
Regulation Of B Cell Proliferation
Positive Regulation Of Macromolecule Biosynthetic Process
Actin Filament-based Movement
Positive Regulation Of Catalytic Activity
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process
Positive Regulation Of Cell Cycle
Actin Filament-based Process
Myofibril Assembly
Transcription, DNA-templated
Organ Development
Muscle Cell Differentiation
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis
Collateral Sprouting In Absence Of Injury
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tissue Development
Protein Stabilization
Developmental Process
Hippo Signaling
Intracellular Signal Transduction
Response To Stimulus
Signaling
Cell Communication
Keratinocyte Differentiation
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Protein Metabolic Process
Signal Transduction
Cellular Response To Stimulus
Regulation Of Cellular Protein Metabolic Process
Epidermal Cell Differentiation
Cell Death
Death
Negative Regulation Of Protein Phosphorylation
Regulation Of Protein Metabolic Process
Regulation Of Apoptotic Process
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Programmed Cell Death
Regulation Of Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of Protein Metabolic Process
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Negative Regulation Of Phosphorylation
Positive Regulation Of Peptidyl-serine Phosphorylation
Regulation Of Cysteine-type Endopeptidase Activity
Negative Regulation Of Protein Kinase Activity
Nitric Oxide Biosynthetic Process
Apoptotic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Organic Substance
Skin Development
Negative Regulation Of Kinase Activity
Programmed Cell Death
Posttranscriptional Regulation Of Gene Expression
Regulation Of Protein Kinase Activity
Mitotic Cell Cycle Phase Transition
Regulation Of Peptidyl-serine Phosphorylation
Cell Cycle Phase Transition
Epidermis Development
Cellular Response To Organic Substance
Negative Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Reactive Oxygen Species Metabolic Process
Positive Regulation Of Proteolysis
Negative Regulation Of Transferase Activity
Epithelial Cell Differentiation
Negative Regulation Of Oxidative Stress-induced Cell Death
Tagcloud
?
contextdependent
crossroads
fat1
fat2
fat3
fat4
fathippo
frmd1
frmd6
gammasecretase
lamellipodia
membraneassociated
mob1a
mob1b
mpdz
mpp5
mupp1
pals1
preball
prognostics
sav1
scribblebinding
stemcell
stk4
vapsbinding
wwc1
wwc2
wwtr1
yap1
Tagcloud (Difference)
?
contextdependent
crossroads
fat1
fat2
fat3
fat4
fathippo
frmd1
frmd6
gammasecretase
lamellipodia
membraneassociated
mob1a
mob1b
mpdz
mpp5
mupp1
pals1
preball
prognostics
sav1
scribblebinding
stemcell
stk4
vapsbinding
wwc1
wwc2
wwtr1
yap1
Tagcloud (Intersection)
?