TPM3 and HDDC3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TPM3	HDDC3
Gene Name		tropomyosin 3	HD domain containing 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Podosome Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Growth Cone Cortical Cytoskeleton Filamentous Actin Cleavage Furrow Extracellular Vesicular Exosome
	Molecular Function	Molecular_function Actin Binding	Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase Activity Metal Ion Binding
	Biological Process	Movement Of Cell Or Subcellular Component Muscle Contraction Muscle Filament Sliding	Metabolic Process
Pathways		Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		41 interactors: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 FAM9C FBXO5 HDDC3 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P	10 interactors: APP CCDC172 CEP57L1 EXOC5 GKAP1 GOLGA8EP GOLGA8F NMI TNIP1 TPM3
Entrez ID		7170	374659
HPRD ID		01840	14635
Ensembl ID		ENSG00000143549	ENSG00000184508
Uniprot IDs		B4DQ80 P06753 Q5VU58 Q5VU63 Q8TCG3	Q8N4P3
PDB IDs			3NR1
Enriched GO Terms of Interacting Partners?		Actomyosin Structure Organization Organelle Organization Actin Filament-based Process Regulation Of Organelle Organization Cellular Component Assembly Actin-myosin Filament Sliding Muscle Filament Sliding Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Cytoskeleton Organization Actin-mediated Cell Contraction Regulation Of Cytoskeleton Organization Actin Filament Organization Actin Filament-based Movement Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Pointed-end Actin Filament Capping Regulation Of Chromosome Segregation Regulation Of Actin Polymerization Or Depolymerization Myofibril Assembly Regulation Of Actin Filament Length Cell-cell Junction Organization Regulation Of Mitotic Cell Cycle Muscle Contraction Cell Division Cell Cycle Muscle System Process Organelle Assembly Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Cell Development Movement Of Cell Or Subcellular Component Mitotic Nuclear Division Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Cellular Component Organization Regulation Of Muscle Contraction Positive Regulation Of Transcription Factor Import Into Nucleus Striated Muscle Cell Development Negative Regulation Of Centriole-centriole Cohesion Positive Regulation Of Transforming Growth Factor Beta3 Production Inhibition Of APC-Cdc20 Complex Activity Regulation Of Metaphase Plate Congression Posterior Compartment Specification Anterior Compartment Pattern Formation Negative Regulation Of Cytoskeleton Organization Regulation Of Mitotic Sister Chromatid Separation Arp2/3 Complex-mediated Actin Nucleation Muscle Cell Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury
Tagcloud ?		aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc	alter bcac belongs casp8 causative combining consortium drosha elucidate gwas machinery meta micrornas mirna mustn1 mycl1 remaining risks rs1045494 rs1052532 rs10719 rs3134615 rs4687554 snps subgroups suggestive utr variations warranted
Tagcloud (Difference) ?		aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc	alter bcac belongs casp8 causative combining consortium drosha elucidate gwas machinery meta micrornas mirna mustn1 mycl1 remaining risks rs1045494 rs1052532 rs10719 rs3134615 rs4687554 snps subgroups suggestive utr variations warranted
Tagcloud (Intersection) ?