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TFPT and TCF3
Number of citations of the paper that reports this interaction (PMID
10086727
)
4
Data Source:
HPRD
(in vitro)
TFPT
TCF3
Gene Name
TCF3 (E2A) fusion partner (in childhood Leukemia)
transcription factor 3
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Actin Filament
Ino80 Complex
Nuclear Membrane
Nuclear Nucleosome
Nuclear Chromatin
Nucleus
Nucleoplasm
Transcription Factor Complex
Cytoplasm
Protein Complex
RNA Polymerase II Transcription Factor Complex
Molecular Function
DNA Binding
Protein Binding
Protein Kinase Binding
Protein Heterodimerization Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
DNA Binding
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Coactivator Activity
Protein Binding
Transcription Factor Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Enhancer Binding
Protein Homodimerization Activity
BHLH Transcription Factor Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Protein Heterodimerization Activity
Repressing Transcription Factor Binding
Vitamin D Response Element Binding
E-box Binding
Biological Process
DNA Repair
DNA Recombination
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Positive Regulation Of Apoptotic Process
Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Natural Killer Cell Differentiation
B Cell Lineage Commitment
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
B Cell Differentiation
Positive Regulation Of B Cell Proliferation
Response To Lipopolysaccharide
T Cell Differentiation In Thymus
Immunoglobulin V(D)J Recombination
Response To Drug
Muscle Cell Differentiation
Histone H3 Acetylation
Histone H4 Acetylation
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Cell Cycle
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cell Development
Peyer's Patch Development
Protein Stabilization
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of Muscle Cell Differentiation
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways
CDO in myogenesis
Myogenesis
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
23 interactors:
APP
C4orf46
CCDC67
CDCA7L
DYDC1
EAF1
EAF2
ELL
HAUS1
KRT19
LMO2
NOL3
PAWR
PIM1
RALBP1
RPGRIP1
RUNDC3A
SDCCAG3
STK3
TCF3
TFIP11
TPM1
TPM3
62 interactors:
AEBP1
ASCL3
BHLHA15
CALM1
CALM3
CBFA2T3
CREBBP
CTNNB1
DAXX
ELK3
EP300
FERD3L
HAND1
HAND2
HOXA1
ID1
ID2
ID3
KAT2A
KAT2B
LMX1A
LMX1B
LYL1
MAPK1
MAPK3
MAPKAPK2
MAPKAPK3
MAX
MDFI
MEN1
MSC
MYF5
MYF6
MYOD1
MYOG
NEDD9
NHLH1
PDX1
PRKACA
PSMD4
PSMD9
RALGAPA1
RPL37
RUFY1
RUNX1T1
SKP2
SRF
SUPT3H
TADA2A
TAL1
TAL2
TCAF1
TCF12
TCF21
TCF4
TFPT
TLE1
TRRAP
TWIST1
UBE2I
USF1
VDR
Entrez ID
29844
6929
HPRD ID
10266
00918
Ensembl ID
ENSG00000105619
ENSG00000071564
Uniprot IDs
P0C1Z6
P15923
Q2TB39
PDB IDs
1HLH
2YPA
2YPB
3U5V
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Metabolic Process
Apoptotic Process
RNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Programmed Cell Death
Regulation Of Metabolic Process
Cell Death
Death
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Gene Expression
Embryo Development
Regulation Of Transcription, DNA-templated
Actin-myosin Filament Sliding
Muscle Filament Sliding
Regulation Of Nucleic Acid-templated Transcription
Embryonic Hemopoiesis
Regulation Of RNA Biosynthetic Process
Cell Differentiation Involved In Embryonic Placenta Development
Regulation Of RNA Metabolic Process
Regulation Of Catalytic Activity
Organelle Assembly
Actin-mediated Cell Contraction
Cellular Component Assembly
In Utero Embryonic Development
Spliceosomal Complex Disassembly
Response To Injury Involved In Regulation Of Muscle Adaptation
Positive Regulation Of Heart Rate By Epinephrine
Sarcomere Organization
Regulation Of B Cell Proliferation
Positive Regulation Of Macromolecule Biosynthetic Process
Actin Filament-based Movement
Positive Regulation Of Catalytic Activity
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process
Positive Regulation Of Cell Cycle
Actin Filament-based Process
Myofibril Assembly
Transcription, DNA-templated
Organ Development
Muscle Cell Differentiation
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis
Collateral Sprouting In Absence Of Injury
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tissue Development
Protein Stabilization
Developmental Process
RNA Biosynthetic Process
Transcription, DNA-templated
Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
RNA Metabolic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Regulation Of RNA Metabolic Process
Macromolecule Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Nitrogen Compound Metabolic Process
Positive Regulation Of Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Organ Development
Cellular Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
System Development
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Process
Anatomical Structure Development
Multicellular Organismal Development
Developmental Process
Embryo Development
Tissue Development
Organ Morphogenesis
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Binding
Embryonic Morphogenesis
Cell Differentiation
Anatomical Structure Morphogenesis
Embryonic Organ Development
Tagcloud
?
advantageous
characterize
chimpanzee
crebbp
eleven
ep300
evolution
fgf2
germ
gorilla
hdac3
macaque
macaques
mapped
microarrays
orangutan
organs
partners
primate
prkd3
profiled
profiling
proteomics
regard
runx1
runx2
satb2
testis
yap1
Tagcloud (Difference)
?
advantageous
characterize
chimpanzee
crebbp
eleven
ep300
evolution
fgf2
germ
gorilla
hdac3
macaque
macaques
mapped
microarrays
orangutan
organs
partners
primate
prkd3
profiled
profiling
proteomics
regard
runx1
runx2
satb2
testis
yap1
Tagcloud (Intersection)
?