TFPT and EAF1

Number of citations of the paper that reports this interaction (PMID 17395368)
1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		TFPT	EAF1
Gene Name		TCF3 (E2A) fusion partner (in childhood Leukemia)	ELL associated factor 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Actin Filament Ino80 Complex Nuclear Membrane	Nucleoplasm Cytoplasm Transcription Elongation Factor Complex Cajal Body Nuclear Speck ELL-EAF Complex
	Molecular Function	DNA Binding Protein Binding Protein Kinase Binding Protein Heterodimerization Activity	Protein Binding
	Biological Process	DNA Repair DNA Recombination Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Apoptotic Process Apoptotic Signaling Pathway	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		23 interactors: APP C4orf46 CCDC67 CDCA7L DYDC1 EAF1 EAF2 ELL HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 RALBP1 RPGRIP1 RUNDC3A SDCCAG3 STK3 TCF3 TFIP11 TPM1 TPM3	13 interactors: AES APP BEND7 CEP76 ELL ELL2 HOMER3 MIPOL1 PSME3 SDCBP TFCP2 TFPT ZBTB14
Entrez ID		29844	85403
HPRD ID		10266	12209
Ensembl ID		ENSG00000105619	ENSG00000144597
Uniprot IDs		P0C1Z6	B4E3F5 Q96JC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Apoptotic Process RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Programmed Cell Death Regulation Of Metabolic Process Cell Death Death Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Embryo Development Regulation Of Transcription, DNA-templated Actin-myosin Filament Sliding Muscle Filament Sliding Regulation Of Nucleic Acid-templated Transcription Embryonic Hemopoiesis Regulation Of RNA Biosynthetic Process Cell Differentiation Involved In Embryonic Placenta Development Regulation Of RNA Metabolic Process Regulation Of Catalytic Activity Organelle Assembly Actin-mediated Cell Contraction Cellular Component Assembly In Utero Embryonic Development Spliceosomal Complex Disassembly Response To Injury Involved In Regulation Of Muscle Adaptation Positive Regulation Of Heart Rate By Epinephrine Sarcomere Organization Regulation Of B Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Actin Filament-based Movement Positive Regulation Of Catalytic Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Cell Cycle Actin Filament-based Process Myofibril Assembly Transcription, DNA-templated Organ Development Muscle Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Collateral Sprouting In Absence Of Injury Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Tissue Development Protein Stabilization Developmental Process	SnRNA Transcription From RNA Polymerase II Promoter SnRNA Transcription Gene Expression SnRNA Metabolic Process RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Glutamate Receptor Signaling Pathway Regulation Of Cellular Process DNA-templated Transcription, Elongation Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Cycle Process Regulation Of RNA Metabolic Process Collateral Sprouting In Absence Of Injury Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Anoikis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Negative Regulation Of Canonical Wnt Signaling Pathway SnRNA Transcription From RNA Polymerase III Promoter Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Gene Expression Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Extracellular Vesicular Exosome Assembly Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Axon Choice Point Recognition Negative Regulation Of Wnt Signaling Pathway Neuron Remodeling Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Catalytic Activity Regulation Of Cell Cycle Phase Transition Positive Regulation Of Exosomal Secretion
Tagcloud ?			5days advance cd71 cd71high coitum counterpart enucleated eryps erythroblasts erythrocyte erythrocytes erythropoiesis esc escs globin hoxb4 klf1 maturational primitive proliferating reflect represented sac segregation switching technical ter119 went yolk
Tagcloud (Difference) ?			5days advance cd71 cd71high coitum counterpart enucleated eryps erythroblasts erythrocyte erythrocytes erythropoiesis esc escs globin hoxb4 klf1 maturational primitive proliferating reflect represented sac segregation switching technical ter119 went yolk
Tagcloud (Intersection) ?