TFPT and CCDC57

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TFPT	CCDC57
Description		TCF3 fusion partner	coiled-coil domain containing 57
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ino80 Complex	Cytoplasm Centrosome Centriole Spindle Cytoskeleton Spindle Microtubule Centriolar Satellite
	Molecular Function	DNA Binding Protein Binding	Protein Binding
	Biological Process	Telomere Maintenance Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair DNA Recombination Chromatin Remodeling Apoptotic Process DNA Damage Response Regulation Of Chromosome Organization Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Apoptotic Signaling Pathway Positive Regulation Of Telomere Maintenance In Response To DNA Damage	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Centriole Replication Positive Regulation Of Mitotic Cell Cycle Cilium Assembly
Pathways		UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Blood urea nitrogen levels ( 31152163) Proteinuria and chronic kidney disease ( 26420894) Refractive error ( 32231278)
Interacting Genes		30 interacting genes: APP C19orf25 C4orf46 CCDC57 CCNDBP1 CDCA7L CNN1 DDIT4L DEUP1 DYDC1 EAF1 EAF2 ELL HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 PIN1 PSMB1 RPGRIP1 RUNDC3A STK3 TCF3 TFIP11 TPM1 TPM2 TPM3 TRAF1	148 interacting genes: ABI1 ABI2 ABLIM1 AMOTL2 ANKRD23 AQP1 ARID5A ARL4A AXIN1 BCAR3 BEX2 C19orf44 CATSPERT CBX8 CBY2 CCDC120 CCDC33 CDC20B CEP57L1 CFAP53 COIL CRTC2 CWF19L2 DCLK2 DISC1 DTX2 ECPAS EFHC2 EIF3D EIF4G1 ELOA EMILIN3 ESS2 FAM107A FAM161A FAM161B FAM228A FAM50B FAM90A1 FH FOXD4L1 FTO GFAP GIGYF1 GPBP1 GPKOW GRPEL1 HAUS1 HBA2 HDX IHO1 IKZF3 INCA1 INTS2 JRK KANK2 KIAA0408 KLF1 KLF15 KPRP KRT4 KRT76 KRTAP13-2 KRTAP13-3 LENG1 LINC00526 LZTS1 MAD1L1 MDM1 MFAP1 MT1E MYOZ3 NAB2 NAPRT NCOA5 NELFE NME4 NUMA1 PAK5 PER1 POM121 PPHLN1 PPP1R18 PRAM1 PRDM6 PROSER3 PRPF18 PRPF31 PRR3 PSMB4 PTCHD3 PTPN7 RAB3IL1 RASD1 RBM48 RDM1 RINT1 RNF6 ROBO3 RUSC1 RXRB SAXO4 SFI1 SH3KBP1 SHISA6 SIRPA SLC25A48 SMG9 SNRNP35 SORBS3 SPMIP2 SPMIP6 SPRY1 SYT6 TBC1D22B TCP10L TFIP11 TFPT TIMM44 TLE5 TMEM100 TNNI1 TP53BP2 TRIM14 TRIM29 TSEN54 TSGA10IP TSHZ2 TXLNA USP15 USP2 UTP14C VPS52 YJU2 ZBTB4 ZC2HC1C ZFC3H1 ZGPAT ZMAT2 ZNF417 ZNF436 ZNF474 ZNF552 ZNF648 ZNF655 ZNF688 ZNF835 ZSWIM3
Entrez ID		29844	284001
HPRD ID		10266	14150
Ensembl ID		ENSG00000105619	ENSG00000176155
Uniprot IDs		P0C1Z6	A0A590UJT6 Q2TAC2
PDB IDs
Enriched GO Terms of Interacting Partners?		Muscle Thin Filament Tropomyosin Supramolecular Fiber Organization Transcription Elongation Factor Complex Actin Filament Super Elongation Complex Actin Filament Organization Structural Constituent Of Muscle Transcription Elongation By RNA Polymerase II Transcription Elongation Factor Activity Cytoskeleton Actin Cytoskeleton DNA-templated Transcription Elongation Regulation Of Extrinsic Apoptotic Signaling Pathway Cytoplasm Actin Binding Actin Filament Binding Microtubule Organizing Center Organization Regulation Of Transcription Elongation By RNA Polymerase II Apoptotic Process Protein Binding Cell Differentiation Involved In Embryonic Placenta Development Nuclear Speck Regulation Of DNA-templated Transcription Elongation Centriole Replication Programmed Cell Death Cell Death Actomyosin Structure Organization	Protein Binding Spliceosomal Complex Nucleus Cytoskeleton MRNA Splicing, Via Spliceosome RNA Splicing Axonemal A Tubule Inner Sheath RNA Splicing, Via Transesterification Reactions
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