TFPT and C4orf46

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		TFPT	C4orf46
Description		TCF3 fusion partner	chromosome 4 open reading frame 46
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Ino80 Complex	Cytoplasm Cytosol
	Molecular Function	DNA Binding Protein Binding	Protein Binding
	Biological Process	Telomere Maintenance Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair DNA Recombination Chromatin Remodeling Apoptotic Process DNA Damage Response Regulation Of Chromosome Organization Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Apoptotic Signaling Pathway Positive Regulation Of Telomere Maintenance In Response To DNA Damage
Pathways		UCH proteinases DNA Damage Recognition in GG-NER
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		30 interacting genes: APP C19orf25 C4orf46 CCDC57 CCNDBP1 CDCA7L CNN1 DDIT4L DEUP1 DYDC1 EAF1 EAF2 ELL HAUS1 KRT19 LMO2 NOL3 PAWR PIM1 PIN1 PSMB1 RPGRIP1 RUNDC3A STK3 TCF3 TFIP11 TPM1 TPM2 TPM3 TRAF1	10 interacting genes: APP BLOC1S6 CDR2 CDR2L HSF2BP HUS1 KXD1 PICK1 SRPK2 TFPT
Entrez ID		29844	201725
HPRD ID		10266	17319
Ensembl ID		ENSG00000105619	ENSG00000205208
Uniprot IDs		P0C1Z6	Q504U0
PDB IDs
Enriched GO Terms of Interacting Partners?		Muscle Thin Filament Tropomyosin Supramolecular Fiber Organization Transcription Elongation Factor Complex Actin Filament Super Elongation Complex Actin Filament Organization Structural Constituent Of Muscle Transcription Elongation By RNA Polymerase II Transcription Elongation Factor Activity Cytoskeleton Actin Cytoskeleton DNA-templated Transcription Elongation Regulation Of Extrinsic Apoptotic Signaling Pathway Cytoplasm Actin Binding Actin Filament Binding Microtubule Organizing Center Organization Regulation Of Transcription Elongation By RNA Polymerase II Apoptotic Process Protein Binding Cell Differentiation Involved In Embryonic Placenta Development Nuclear Speck Regulation Of DNA-templated Transcription Elongation Centriole Replication Programmed Cell Death Cell Death Actomyosin Structure Organization	Cytoskeleton-dependent Intracellular Transport Transport Along Microtubule Microtubule-based Transport Organelle Transport Along Microtubule BLOC-1 Complex Microtubule-based Movement Positive Regulation Of Receptor Internalization Amyloid-beta Complex Presynapse Growth Cone Lamellipodium Neuron Projection Organization Intracellular Transport Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Bradykinin Biosynthetic Process Vesicle Cytoskeletal Trafficking Vesicle Transport Along Microtubule Establishment Of Organelle Localization Circadian Sleep/wake Cycle Glial Cell Development Positive Regulation Of Neuron Apoptotic Process G Protein-coupled Receptor Binding Microtubule-based Process Regulation Of Receptor Internalization Axo-dendritic Transport Cellular Localization Establishment Of Localization In Cell Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Meiotic DNA Integrity Checkpoint Signaling PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Telomere Maintenance Intracellular Nitric Oxide Homeostasis Establishment Of Vesicle Localization Golgi To Secretory Granule Transport Trans-Golgi Network Membrane Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus
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