TPM3 and IKBIP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TPM3	IKBIP
Gene Name		tropomyosin 3	IKBKB interacting protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Podosome Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Growth Cone Cortical Cytoskeleton Filamentous Actin Cleavage Furrow Extracellular Vesicular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Actin Binding	Protein Binding
	Biological Process	Movement Of Cell Or Subcellular Component Muscle Contraction Muscle Filament Sliding	Response To X-ray
Pathways		Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		41 interactors: ACTA1 ACTB BLOC1S6 C1orf216 CCDC102B CCDC114 CCDC146 CCHCR1 CNN1 FAM9C FBXO5 HDDC3 HSF2 IFIT3 IKBIP KCNE1 KIFC3 KXD1 LCA5L LURAP1 MAD1L1 MAGEA11 NEK2 OIP5 PBX3 S100A2 S100A4 SMAD3 SUMO4 SYCE1 TFPT THAP1 TLK1 TMOD1 TMOD2 TNNT1 TRAP1 TRIM27 TRIP6 VPS52 WASH3P	8 interactors: APP C9orf16 KDM1A KRT15 MYOG NUP62 TFIP11 TPM3
Entrez ID		7170	121457
HPRD ID		01840	08092
Ensembl ID		ENSG00000143549	ENSG00000166130
Uniprot IDs		B4DQ80 P06753 Q5VU58 Q5VU63 Q8TCG3	Q70UQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Actomyosin Structure Organization Organelle Organization Actin Filament-based Process Regulation Of Organelle Organization Cellular Component Assembly Actin-myosin Filament Sliding Muscle Filament Sliding Actin Cytoskeleton Organization Regulation Of Actin Filament-based Process Cytoskeleton Organization Actin-mediated Cell Contraction Regulation Of Cytoskeleton Organization Actin Filament Organization Actin Filament-based Movement Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Pointed-end Actin Filament Capping Regulation Of Chromosome Segregation Regulation Of Actin Polymerization Or Depolymerization Myofibril Assembly Regulation Of Actin Filament Length Cell-cell Junction Organization Regulation Of Mitotic Cell Cycle Muscle Contraction Cell Division Cell Cycle Muscle System Process Organelle Assembly Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Cell Development Movement Of Cell Or Subcellular Component Mitotic Nuclear Division Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Cellular Component Organization Regulation Of Muscle Contraction Positive Regulation Of Transcription Factor Import Into Nucleus Striated Muscle Cell Development Negative Regulation Of Centriole-centriole Cohesion Positive Regulation Of Transforming Growth Factor Beta3 Production Inhibition Of APC-Cdc20 Complex Activity Regulation Of Metaphase Plate Congression Posterior Compartment Specification Anterior Compartment Pattern Formation Negative Regulation Of Cytoskeleton Organization Regulation Of Mitotic Sister Chromatid Separation Arp2/3 Complex-mediated Actin Nucleation Muscle Cell Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Spliceosomal Complex Disassembly Positive Regulation Of Muscle Atrophy Regulation Of Primitive Erythrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Synaptic Growth At Neuromuscular Junction Positive Regulation Of Macromolecule Biosynthetic Process Collateral Sprouting In Absence Of Injury Positive Regulation Of Gene Expression Regulation Of Protein Binding Positive Regulation Of Cellular Biosynthetic Process Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Muscle Cell Development Collateral Sprouting Axon Midline Choice Point Recognition RNA Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Skeletal Muscle Fiber Development Striated Muscle Atrophy Positive Regulation Of Cell Cycle Process Gene Expression Negative Regulation Of Protein Metabolic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Muscle Atrophy Histone H3-K4 Demethylation Developmental Process Regulation Of Satellite Cell Proliferation Neuron Remodeling Response To Denervation Involved In Regulation Of Muscle Adaptation Regulation Of Binding Muscle System Process Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Cycle Positive Regulation Of Hormone Biosynthetic Process Response To Inactivity MRNA Transcription From RNA Polymerase II Promoter Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Response To Muscle Activity Muscle Cell Differentiation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator MRNA Transcription Granulocyte Differentiation
Tagcloud ?		aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc
Tagcloud (Difference) ?		aacr accelerated advancements ago approved developments discov encodes fda fusions harboring next ntrk1 oncd oncogene oncogenic oncology originally precision rationale rearrangements revisit scientific throughput transforming trk trka trkb trkc
Tagcloud (Intersection) ?