DDB2 and USP24

Number of citations of the paper that reports this interaction (PMID 23159851)
3

Data Source:
BioGRID (enzymatic study)

		DDB2	USP24
Gene Name		damage-specific DNA binding protein 2, 48kDa	ubiquitin specific peptidase 24
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cell Junction Cul4B-RING E3 Ubiquitin Ligase Complex Protein Complex
	Molecular Function	DNA Binding Damaged DNA Binding Ubiquitin-protein Transferase Activity Protein Binding	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity
	Biological Process	Protein Polyubiquitination Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Pyrimidine Dimer Repair Response To UV Histone H2A Monoubiquitination Protein Autoubiquitination UV-damage Excision Repair	Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways		Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER Dual incision reaction in GG-NER
Drugs
Diseases
GWAS			Metabolite levels ( 22916037)
Protein-Protein Interactions		15 interactors: ABL1 CUL4A CUL4B DCLRE1C DDB1 E2F1 HDAC1 HIST2H2AC HIST2H3C NTMT1 TOP1 USP24 USP40 XPA XPC	3 interactors: CSNK2A1 DDB2 JUNB
Entrez ID		1643	23358
HPRD ID		02886	11664
Ensembl ID		ENSG00000134574	ENSG00000162402
Uniprot IDs		Q92466	Q9UPU5
PDB IDs		3EI4 3I7L 4E54 4E5Z
Enriched GO Terms of Interacting Partners?		DNA Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process DNA Repair Regulation Of Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Removal Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Catabolic Process Regulation Of Cell Cycle Cellular Response To Stress Response To UV DNA Catabolic Process Intrinsic Apoptotic Signaling Pathway Response To Radiation Response To Stress UV-damage Excision Repair Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization Histone H2A Monoubiquitination Nucleotide-excision Repair Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Abiotic Stimulus Histone H2A Ubiquitination Response To Light Stimulus Positive Regulation Of Mitotic Cell Cycle Apoptotic Signaling Pathway Nitrogen Compound Metabolic Process Cellular Metabolic Process Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Histone Monoubiquitination Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Aromatic Compound Catabolic Process Negative Regulation Of Cell Cycle Interaction With Symbiont	Response To Light Stimulus UV-damage Excision Repair Osteoblast Proliferation Response To Radiation Embryonic Process Involved In Female Pregnancy Histone H2A Monoubiquitination Pyrimidine Dimer Repair Histone H2A Ubiquitination Nucleotide-excision Repair, DNA Damage Removal Histone Monoubiquitination Trophectodermal Cell Differentiation Labyrinthine Layer Blood Vessel Development Decidualization Response To Corticosterone Histone Ubiquitination Regulation Of Cell Cycle Response To Mineralocorticoid Placenta Blood Vessel Development Mitotic Spindle Checkpoint Blastocyst Formation Protein Monoubiquitination Negative Regulation Of Chromosome Segregation Maternal Placenta Development Protein Autoubiquitination Osteoclast Differentiation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Response To Abiotic Stimulus Cellular Response To Calcium Ion Response To Progesterone Regulation Of Mitotic Metaphase/anaphase Transition
Tagcloud ?		adherens bioassays bladder carcinogenic carcinogens chemicals consistently construct discriminate evaluating foundation gadd45a genotoxic genotoxicity globaltest hepg2 implemented industry investigating junction microarrays pam peroxisome perturbation pharmaceutical rrm2b set sets validate	additionally cleave corrected depleted depletion destabilization deubiquitinase deubiquitinates deubiquitination forced hprt implying importantly irradiation locus maintaining p53 puma purified regulates renders requirement reveal stability stabilization suppressor ubiquitinated ubiquitination uv
Tagcloud (Difference) ?		adherens bioassays bladder carcinogenic carcinogens chemicals consistently construct discriminate evaluating foundation gadd45a genotoxic genotoxicity globaltest hepg2 implemented industry investigating junction microarrays pam peroxisome perturbation pharmaceutical rrm2b set sets validate	additionally cleave corrected depleted depletion destabilization deubiquitinase deubiquitinates deubiquitination forced hprt implying importantly irradiation locus maintaining p53 puma purified regulates renders requirement reveal stability stabilization suppressor ubiquitinated ubiquitination uv
Tagcloud (Intersection) ?