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CRIPTO and COPS6
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CRIPTO
COPS6
Description
cripto, EGF-CFC family member
COP9 signalosome subunit 6
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Plasma Membrane
Cell Surface
Membrane
Apical Plasma Membrane
Membrane Raft
Side Of Membrane
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
COP9 Signalosome
Perinuclear Region Of Cytoplasm
Molecular Function
Signaling Receptor Binding
Protein Binding
Growth Factor Activity
Nodal Binding
Activin Receptor Binding
Protein Binding
Peptidase Activity
Metal-dependent Deubiquitinase Activity
Biological Process
Blood Vessel Development
Morphogenesis Of A Branching Structure
Cell Migration Involved In Sprouting Angiogenesis
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Determination Of Left/right Symmetry
Heart Development
Positive Regulation Of Cell Population Proliferation
Anterior/posterior Axis Specification, Embryo
Embryo Development Ending In Birth Or Egg Hatching
Anterior/posterior Pattern Specification
Regulation Of Signal Transduction
Positive Regulation Of Endothelial Cell Migration
Cell Differentiation
Positive Regulation Of Cell Migration
Mammary Gland Development
Cellular Response To Hepatocyte Growth Factor Stimulus
Nodal Signaling Pathway
Negative Regulation Of Apoptotic Process
Positive Regulation Of MAP Kinase Activity
Positive Regulation Of MAPK Cascade
Cellular Response To Fibroblast Growth Factor Stimulus
Cellular Response To Type II Interferon
Cellular Response To Interleukin-6
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Protein Deneddylation
Protein Neddylation
Regulation Of Protein Neddylation
Pathways
Signaling by NODAL
Regulation of signaling by NODAL
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
22 interacting genes:
ACVR1
ACVR1B
ACVR1C
ACVR2A
ACVR2B
ANG
AP2S1
BAG6
BMP4
BMP6
BMP7
BMPR1A
BMPR2
COPS6
FARSA
FBLN1
GDF3
GDF9
INHBB
LRIF1
NODAL
TGFBR2
95 interacting genes:
ANXA1
ANXA7
ASH2L
BFSP2
BTBD2
C1orf174
C4orf17
CASP3
CASP6
CASP7
CASP8
CCBE1
CCDC106
CDH10
CDKN1A
CDKN2C
CHRNB1
COPS2
COPS3
COPS4
COPS5
COPS8
COX17
COX5A
CRELD1
CRIPTO
CUL1
CUL5
DIS3L2
DLEU1
DSP
EDN1
EIF3E
EMD
EP300
ERH
FAU
GPS1
HMOX2
LAMA4
LPL
MAP3K1
MAP7D1
MAPK1
MAPK6
MAPKAPK3
MIF
MNAT1
MYCBP
NEDD8
NR3C1
ORAI2
PAEP
PAFAH1B3
PBX2
PDZK1IP1
PFKL
PHYHIP
PMF1
PRKRA
PSAP
PSMD11
PTEN
QTRT1
RAB27A
RBX1
RFC5
ROGDI
RPA2
RPL15
S100A10
SAT1
SERPINA5
SERPINB9
SHANK3
SHC3
SLC2A1
SMN1
SNRPG
STAMBPL1
STK40
STX5
SULT1E1
TK1
TP53
TP63
TRDMT1
TRIB3
UBC
USHBP1
VIM
WIPI2
ZEB2
ZFHX3
ZNF24
Entrez ID
6997
10980
HPRD ID
01757
16735
Ensembl ID
ENSG00000241186
ENSG00000168090
Uniprot IDs
F5H1T8
P13385
Q7L5N1
PDB IDs
4D10
4D18
4QFT
4R14
4WSN
6R6H
6R7F
6R7H
6R7I
8H38
8H3A
8H3F
Enriched GO Terms of Interacting Partners
?
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Activin Receptor Signaling Pathway
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of SMAD Protein Signal Transduction
Activin Receptor Complex
Enzyme-linked Receptor Protein Signaling Pathway
Regulation Of SMAD Protein Signal Transduction
Positive Regulation Of Bone Mineralization
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
BMP Signaling Pathway
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Ossification
Cellular Response To BMP Stimulus
Cellular Response To Growth Factor Stimulus
Regulation Of Ossification
Positive Regulation Of Osteoblast Differentiation
Regulation Of Bone Mineralization
Response To Growth Factor
Activin Receptor Activity, Type I
Activin Binding
Cell Surface Receptor Signaling Pathway
Activin Receptor Activity
Regulation Of Osteoblast Differentiation
Growth Factor Binding
Mesoderm Formation
System Development
Lung Development
Mesoderm Development
Animal Organ Development
Regulation Of Multicellular Organismal Development
Formation Of Primary Germ Layer
BMP Receptor Activity
Osteoblast Differentiation
Outflow Tract Septum Morphogenesis
Tissue Development
Cardiac Septum Morphogenesis
Growth Factor Activity
Pattern Specification Process
Heart Development
Regulation Of Multicellular Organismal Process
Activin Receptor Activity, Type II
Regulation Of Reproductive Process
Positive Regulation Of Cell Differentiation
Developmental Process Involved In Reproduction
Gastrulation
Gastrulation With Mouth Forming Second
Cytokine Activity
Heart Valve Morphogenesis
Protein Neddylation
Protein Deneddylation
Regulation Of Protein Neddylation
Nucleoplasm
Heart Development
COP9 Signalosome
Developmental Process
Cytosol
Cellular Response To Staurosporine
Intrinsic Apoptotic Signaling Pathway
Regulation Of Protein Metabolic Process
Ubiquitin Protein Ligase Binding
Signal Transduction By P53 Class Mediator
Cellular Response To Nutrient Levels
Protein Binding
Positive Regulation Of Neuron Apoptotic Process
Protease Binding
Pyroptotic Inflammatory Response
Protein Modification By Small Protein Removal
Nucleus
Animal Organ Development
Regulation Of Cell Cycle G1/S Phase Transition
Cytoplasm
Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Cellular Developmental Process
Cell Differentiation
Macromolecule Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Keratinocyte Differentiation
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Positive Regulation Of Macromolecule Metabolic Process
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Scaffold Protein Binding
MAPK Cascade
Cellular Response To Alkaloid
Regulation Of Protein Modification Process
Positive Regulation Of Programmed Cell Death
Post-translational Protein Modification
Protein Modification Process
Regulation Of Post-translational Protein Modification
Protein Tag Activity
Cullin-RING Ubiquitin Ligase Complex
Protein-containing Complex
Cellular Response To Starvation
Response To Nutrient Levels
Mitotic G1 DNA Damage Checkpoint Signaling
Rhythmic Synaptic Transmission
G1/S Transition Of Mitotic Cell Cycle
Mitotic G1/S Transition Checkpoint Signaling
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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