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SYT4 and SYT1
Number of citations of the paper that reports this interaction (PMID
10397765
)
9
Data Source:
HPRD
(in vitro)
SYT4
SYT1
Gene Name
synaptotagmin IV
synaptotagmin I
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Cell Junction
Synaptic Vesicle Membrane
Dense Core Granule
Neuron Projection
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Plasma Membrane
Synaptic Vesicle
Integral Component Of Membrane
Cell Junction
Synaptic Vesicle Membrane
Dense Core Granule
SNARE Complex
Chromaffin Granule Membrane
Presynaptic Membrane
Neuron Projection
Excitatory Synapse
Clathrin-sculpted Acetylcholine Transport Vesicle Membrane
Clathrin-sculpted Glutamate Transport Vesicle Membrane
Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
Clathrin-sculpted Monoamine Transport Vesicle Membrane
Molecular Function
SNARE Binding
Phosphatidylserine Binding
Transporter Activity
Calcium Ion Binding
Clathrin Binding
SNARE Binding
Phosphatidylserine Binding
Transporter Activity
Calcium Ion Binding
Protein Binding
Calmodulin Binding
Calcium-dependent Phospholipid Binding
1-phosphatidylinositol Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Protein C-terminus Binding
Syntaxin-1 Binding
Clathrin Binding
Identical Protein Binding
Calcium-dependent Protein Binding
Low-density Lipoprotein Particle Receptor Binding
Biological Process
Exocytosis
Neurotransmitter Secretion
Negative Regulation Of Vesicle Fusion
Negative Regulation Of Calcium Ion-dependent Exocytosis
Detection Of Calcium Ion
Synaptic Transmission
Neurotransmitter Secretion
Pathogenesis
Glutamate Secretion
Synaptic Vesicle Exocytosis
Regulation Of Exocytosis
Positive Regulation Of Vesicle Fusion
Positive Regulation Of Calcium Ion-dependent Exocytosis
Vesicle Docking
Positive Regulation Of Synaptic Transmission
Protein Homooligomerization
Regulation Of Synaptic Transmission, Glutamatergic
Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter
Regulation Of Regulated Secretory Pathway
Pathways
Dopamine Neurotransmitter Release Cycle
Toxicity of botulinum toxin type G (BoNT/G)
Acetylcholine Neurotransmitter Release Cycle
Norepinephrine Neurotransmitter Release Cycle
GABA synthesis, release, reuptake and degradation
Glutamate Neurotransmitter Release Cycle
Uptake and actions of bacterial toxins
Neurotransmitter Release Cycle
Toxicity of botulinum toxin type B (BoNT/B)
Neurotoxicity of clostridium toxins
Serotonin Neurotransmitter Release Cycle
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Parkinson's disease (
21738487
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
10 interactors:
NBR1
NRXN1
SGTA
STX1A
STX2
STX3
STX4
SYNCRIP
SYT1
TFAP2B
30 interactors:
CACNA1A
CACNB3
CACNB4
CALM1
FGF1
GNB2L1
GOLM1
IKBKG
IRF3
NEDD4
NR1H3
NR3C1
NRXN1
PPARG
RBM14
RIMS1
S100A13
SIN3A
SMAD2
SNAP25
STON2
STX1A
STX2
STX3
STX4
SV2B
SYNCRIP
SYT4
TFAP2A
ZDHHC17
Entrez ID
6860
6857
HPRD ID
02519
01710
Ensembl ID
ENSG00000132872
ENSG00000067715
Uniprot IDs
B4DEU3
Q9H2B2
J3KQA0
P21579
PDB IDs
1UGK
2K45
2K4A
2K8M
2KI6
2LHA
2R83
3F00
3F01
3F04
3F05
4ISQ
Enriched GO Terms of Interacting Partners
?
Neurotransmitter Secretion
Synaptic Vesicle Fusion To Presynaptic Membrane
Regulation Of Neurotransmitter Levels
Synaptic Vesicle Exocytosis
Neurotransmitter Transport
Vesicle Localization
Vesicle Docking
Membrane Docking
Positive Regulation Of Synaptic Transmission
Synaptic Vesicle Transport
Vesicle Fusion
Organelle Localization
Establishment Of Vesicle Localization
Secretion By Cell
Organelle Fusion
Synaptic Transmission
Secretion
Regulation Of Synaptic Transmission
Establishment Of Organelle Localization
Exocytosis
Positive Regulation Of Protein Localization To Plasma Membrane
Membrane Fusion
Cell-cell Signaling
Regulation Of Insulin Secretion
Vesicle Organization
Regulation Of Cellular Localization
Regulation Of Protein Localization To Plasma Membrane
Regulation Of Peptide Hormone Secretion
Positive Regulation Of Exocytosis
Regulation Of Hormone Secretion
Regulation Of Secretion
Positive Regulation Of Protein Localization To Cell Surface
Regulation Of Protein Localization
Membrane Organization
Regulation Of Protein Secretion
Regulation Of Exocytosis
Regulation Of Protein Localization To Cell Surface
Protein Complex Assembly
Response To Hydroperoxide
Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane
Glutamate Secretion
Regulation Of Cellular Component Organization
Regulation Of Signaling
Regulation Of Behavior
Establishment Of Localization In Cell
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Protein Transport
Cellular Protein Localization
Regulation Of Establishment Of Protein Localization
Regulation Of Regulated Secretory Pathway
Cell-cell Signaling
Neurotransmitter Transport
Neurotransmitter Secretion
Regulation Of Neurotransmitter Levels
Secretion
Secretion By Cell
Synaptic Vesicle Fusion To Presynaptic Membrane
Synaptic Transmission
Vesicle Localization
Regulation Of Cellular Localization
Exocytosis
Regulation Of Signaling
Organelle Localization
Synaptic Vesicle Exocytosis
Synaptic Vesicle Transport
Signaling
Establishment Of Vesicle Localization
Regulation Of Cellular Component Organization
Cell Communication
Establishment Of Localization In Cell
Intracellular Receptor Signaling Pathway
Cellular Localization
Establishment Of Organelle Localization
Vesicle Fusion
Vesicle-mediated Transport
Membrane Depolarization
Membrane Fusion
Acid Secretion
Regulation Of Vesicle-mediated Transport
Protein Localization
Regulation Of Protein Localization
Regulation Of Membrane Potential
Organelle Fusion
Regulation Of Secretion
Glucocorticoid Receptor Signaling Pathway
Regulation Of Immune Response
Vesicle Docking
Transport
Regulation Of Synaptic Transmission
Establishment Of Protein Localization
Membrane Docking
Regulation Of Signal Transduction
Positive Regulation Of Synaptic Transmission
Calcium Ion-dependent Exocytosis
Regulation Of Protein Secretion
Regulation Of Cellular Process
Cell Differentiation
Protein Transport
Regulation Of Protein Localization To Plasma Membrane
Membrane Organization
Tagcloud
?
carboxyl
conformation
enriched
inactivation
localization
microdomain
microdomains
mode
must
notably
orai1
p2
pi
pm
probe
reveals
rich
saraf
scdi
septin4
slow
stabilized
stim1
store
terminus
tethered
tethers
translocates
undergoes
Tagcloud (Difference)
?
carboxyl
conformation
enriched
inactivation
localization
microdomain
microdomains
mode
must
notably
orai1
p2
pi
pm
probe
reveals
rich
saraf
scdi
septin4
slow
stabilized
stim1
store
terminus
tethered
tethers
translocates
undergoes
Tagcloud (Intersection)
?