SYT4 and TFAP2B

Number of citations of the paper that reports this interaction (PMID 7993622)
37

Data Source:
HPRD (in vivo)

		SYT4	TFAP2B
Gene Name		synaptotagmin IV	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Cell Junction Synaptic Vesicle Membrane Dense Core Granule Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	SNARE Binding Phosphatidylserine Binding Transporter Activity Calcium Ion Binding Clathrin Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Coactivator Activity RNA Polymerase II Transcription Corepressor Activity Enhancer Sequence-specific DNA Binding DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein Homodimerization Activity Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Sequence-specific DNA Binding Protein Heterodimerization Activity Protein Dimerization Activity
	Biological Process	Exocytosis Neurotransmitter Secretion Negative Regulation Of Vesicle Fusion Negative Regulation Of Calcium Ion-dependent Exocytosis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Renal Water Homeostasis Glucose Metabolic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Response To Lithium Ion Retina Layer Formation Magnesium Ion Homeostasis Regulation Of BMP Signaling Pathway Forelimb Morphogenesis Hindlimb Morphogenesis Positive Regulation Of Urine Volume Aorta Morphogenesis Response To Drug Glucose Homeostasis Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Skin Development Fat Cell Differentiation Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Sympathetic Nervous System Development Regulation Of Insulin Secretion Phosphate Ion Homeostasis Calcium Ion Homeostasis Potassium Ion Homeostasis Sodium Ion Homeostasis Distal Tubule Development Collecting Duct Development Metanephric Nephron Development Ductus Arteriosus Closure Cellular Ammonia Homeostasis Cellular Creatinine Homeostasis Cellular Urea Homeostasis
Pathways
Drugs
Diseases
GWAS		Parkinson's disease ( 21738487)	Adiposity ( 19557161) Body mass index ( 23563607 20935630) Metabolic syndrome (bivariate traits) ( 21386085) Obesity ( 23563607) Obesity (extreme) ( 21935397) Renal function-related traits (BUN) ( 22797727)
Protein-Protein Interactions		10 interactors: NBR1 NRXN1 SGTA STX1A STX2 STX3 STX4 SYNCRIP SYT1 TFAP2B	11 interactors: CITED1 CITED2 CITED4 HIST1H2AC LZTR1 MYC SSBP4 SYT4 UBE2I VPS11 YEATS4
Entrez ID		6860	7021
HPRD ID		02519	03360
Ensembl ID		ENSG00000132872	ENSG00000008196
Uniprot IDs		B4DEU3 Q9H2B2	Q92481
PDB IDs		1UGK
Enriched GO Terms of Interacting Partners?		Neurotransmitter Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Vesicle Localization Vesicle Docking Membrane Docking Positive Regulation Of Synaptic Transmission Synaptic Vesicle Transport Vesicle Fusion Organelle Localization Establishment Of Vesicle Localization Secretion By Cell Organelle Fusion Synaptic Transmission Secretion Regulation Of Synaptic Transmission Establishment Of Organelle Localization Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane Membrane Fusion Cell-cell Signaling Regulation Of Insulin Secretion Vesicle Organization Regulation Of Cellular Localization Regulation Of Protein Localization To Plasma Membrane Regulation Of Peptide Hormone Secretion Positive Regulation Of Exocytosis Regulation Of Hormone Secretion Regulation Of Secretion Positive Regulation Of Protein Localization To Cell Surface Regulation Of Protein Localization Membrane Organization Regulation Of Protein Secretion Regulation Of Exocytosis Regulation Of Protein Localization To Cell Surface Protein Complex Assembly Response To Hydroperoxide Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Glutamate Secretion Regulation Of Cellular Component Organization Regulation Of Signaling Regulation Of Behavior Establishment Of Localization In Cell Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Protein Transport Cellular Protein Localization Regulation Of Establishment Of Protein Localization Regulation Of Regulated Secretory Pathway	Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Organ Morphogenesis Response To Estrogen Positive Regulation Of Transcription, DNA-templated Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Branching Involved In Ureteric Bud Morphogenesis Ureteric Bud Morphogenesis Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Response To Interleukin-11 Positive Regulation Of SUMO Transferase Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nephron Morphogenesis Renal Tubule Morphogenesis Regulation Of RNA Metabolic Process Renal Tubule Development Negative Regulation Of Transcription, DNA-templated Kidney Morphogenesis Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Adrenal Cortex Formation Fibroblast Apoptotic Process Response To Steroid Hormone Axis Specification Regulation Of Gene Expression Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Mesonephros Development Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Response To Interleukin-9 Transcription, DNA-templated Negative Regulation Of Gene Expression Nephron Development Negative Regulation Of Biosynthetic Process Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia RNA Biosynthetic Process Kidney Epithelium Development Embryonic Heart Tube Left/right Pattern Formation Positive Regulation Of Cellular Metabolic Process Determination Of Left/right Asymmetry In Lateral Mesoderm
Tagcloud ?			438delccgg 5g abnormalities arteriosus char cited2 coactivator congenital constructed cpb defects ductus express facial familial families fingers haploinsufficiency interacting luciferase mutated mutations patent pda plasmids transactivation transactivator transfected
Tagcloud (Difference) ?			438delccgg 5g abnormalities arteriosus char cited2 coactivator congenital constructed cpb defects ductus express facial familial families fingers haploinsufficiency interacting luciferase mutated mutations patent pda plasmids transactivation transactivator transfected
Tagcloud (Intersection) ?