SYT4

Gene Name		synaptotagmin IV
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Cell Junction Synaptic Vesicle Membrane Dense Core Granule Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	SNARE Binding Phosphatidylserine Binding Transporter Activity Calcium Ion Binding Clathrin Binding
	Biological Process	Exocytosis Neurotransmitter Secretion Negative Regulation Of Vesicle Fusion Negative Regulation Of Calcium Ion-dependent Exocytosis
Pathways
Drugs
Diseases
GWAS		Parkinson's disease ( 21738487)
Protein-protein Interactions		10 interactors: NBR1 NRXN1 SGTA STX1A STX2 STX3 STX4 SYNCRIP SYT1 TFAP2B
Entrez ID		6860
HPRD ID		02519
Ensembl ID		ENSG00000132872
Uniprot IDs		B4DEU3 Q9H2B2
PDB IDs		1UGK
Enriched GO Terms of Interacting Partners?		Neurotransmitter Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Vesicle Localization Vesicle Docking Membrane Docking Positive Regulation Of Synaptic Transmission Synaptic Vesicle Transport Vesicle Fusion Organelle Localization Establishment Of Vesicle Localization Secretion By Cell Organelle Fusion Synaptic Transmission Secretion Regulation Of Synaptic Transmission Establishment Of Organelle Localization Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane Membrane Fusion Cell-cell Signaling Regulation Of Insulin Secretion Vesicle Organization Regulation Of Cellular Localization Regulation Of Protein Localization To Plasma Membrane Regulation Of Peptide Hormone Secretion Positive Regulation Of Exocytosis Regulation Of Hormone Secretion Regulation Of Secretion Positive Regulation Of Protein Localization To Cell Surface Regulation Of Protein Localization Membrane Organization Regulation Of Protein Secretion Regulation Of Exocytosis Regulation Of Protein Localization To Cell Surface Protein Complex Assembly Response To Hydroperoxide Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Glutamate Secretion Regulation Of Cellular Component Organization Regulation Of Signaling Regulation Of Behavior Establishment Of Localization In Cell Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Protein Transport Cellular Protein Localization Regulation Of Establishment Of Protein Localization Regulation Of Regulated Secretory Pathway
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