SYT4 and SYNCRIP

Number of citations of the paper that reports this interaction (PubMedID 10734137)
0

Data Source:
HPRD (in vitro, in vivo)

		SYT4	SYNCRIP
Description		synaptotagmin 4	synaptotagmin binding cytoplasmic RNA interacting protein
Image
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Plasma Membrane Membrane Axon Dendrite Synaptic Vesicle Membrane Dense Core Granule Cytoplasmic Vesicle Vesicle Dense Core Granule Membrane Somatodendritic Compartment Neuron Projection Neuronal Cell Body Synapse Perinuclear Region Of Cytoplasm Exocytic Vesicle Astrocyte Projection Glutamatergic Synapse Neuronal Dense Core Vesicle Neuronal Dense Core Vesicle Membrane Microvesicle	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Endoplasmic Reticulum Cytosol Membrane MRNA Editing Complex CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex MCRD-mediated MRNA Stability Complex Ribonucleoprotein Complex
	Molecular Function	SNARE Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding Calcium Ion Sensor Activity	Nucleic Acid Binding RNA Binding Protein Binding MRNA 5'-UTR Binding
	Biological Process	Vesicle Fusion Neurotransmitter Secretion Memory Positive Regulation Of Glutamate Secretion Regulation Of Dopamine Secretion Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Endocytosis Cell Differentiation Regulation Of Vesicle Fusion Negative Regulation Of Catecholamine Secretion Negative Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Protein Secretion Calcium-dependent Activation Of Synaptic Vesicle Fusion Dense Core Granule Cytoskeletal Transport Regulation Of Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Regulation Of Postsynaptic Dense Core Vesicle Exocytosis Negative Regulation Of Secretion By Cell Positive Regulation Of Dendrite Extension Positive Regulation Of Dense Core Granule Exocytosis Negative Regulation Of Retrograde Trans-synaptic Signaling By Neuropeptide Negative Regulation Of Synaptic Vesicle Exocytosis	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing MRNA Processing Regulation Of Translation RNA Splicing MRNA Modification Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Type II Interferon Chromosomal 5-methylcytosine DNA Demethylation Pathway Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Positive Regulation Of Cytoplasmic Translation
Pathways
Drugs
Diseases
GWAS		Accelerometer-based physical activity measurement (average acceleration) ( 29899525) Body mass index ( 25673413 28892062) Carotid intima media thickness x smoking interaction ( 32117412) Ceramide levels (C24:0) ( 32489964) Coffee consumption ( 31046077) Metabolite levels ( 23823483) Parkinson's disease ( 28892059 21738487) Physical activity (moderate intensity activity duration) ( 30531941) Physical activity (overall physical activity time) ( 30531941) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Pulse pressure ( 27841878) Pyoderma gangrenosum in inflammatory bowel disease ( 24487271) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 27841878) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483)
Interacting Genes		13 interacting genes: BRWD1 NBR1 NDUFA12 NRXN1 SGTA SGTB STX1A STX2 STX3 STX4 SYNCRIP SYT1 TFAP2B	111 interacting genes: A1CF APOBEC1 APP CEBPA CIP2A CSDE1 EPRS1 ESR1 FNDC3B GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYPOP NUPR1 OGT PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SUMO2 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9 TRIM55 TRIM63
Entrez ID		6860	10492
HPRD ID		02519	06734
Ensembl ID		ENSG00000132872	ENSG00000135316
Uniprot IDs		Q9H2B2	A0A7I2V309 A0A7I2YQN2 B7Z645 O60506 Q59GL1
PDB IDs		1UGK	2DGU 2MXT 2NBB 6KOR
Enriched GO Terms of Interacting Partners?		SNARE Binding Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Neurotransmitter Transport Organelle Membrane Fusion SNAP Receptor Activity SNARE Complex Organelle Fusion Positive Regulation Of Synaptic Transmission Membrane Fusion Secretion By Cell Exocytosis Calcium-dependent Protein Binding Organelle Localization TRC Complex Secretion Vesicle Organization Membrane Organization Positive Regulation Of Regulated Secretory Pathway Cornified Envelope Assembly Membrane Assembly Establishment Of Protein Localization Positive Regulation Of Protein Localization To Plasma Membrane Modulation Of Chemical Synaptic Transmission Positive Regulation Of Protein Localization To Cell Periphery Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Endomembrane System Positive Regulation Of Catecholamine Secretion SNARE Complex Assembly Positive Regulation Of Exocytosis Positive Regulation Of Protein Localization To Membrane Glutamatergic Synapse Vesicle-mediated Transport In Synapse Cellular Localization Specific Granule Schaffer Collateral - CA1 Synapse Secretory Granule Positive Regulation Of Calcium Ion-dependent Exocytosis Vacuole Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface Neuron Projection Positive Regulation Of Neurotransmitter Secretion Regulation Of Regulated Secretory Pathway Membrane Presynaptic Membrane Protein Heterooligomerization Regulation Of Protein Localization To Cell Periphery	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Translation RNA Destabilization Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Metabolic Process Negative Regulation Of Cytokine Production Regulation Of RNA Stability Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Locomotion Regulation Of MRNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?