SYT4 and SYNCRIP

Number of citations of the paper that reports this interaction (PMID 10734137)
17

Data Source:
HPRD (in vivo, in vitro)

		SYT4	SYNCRIP
Gene Name		synaptotagmin IV	synaptotagmin binding, cytoplasmic RNA interacting protein
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Cell Junction Synaptic Vesicle Membrane Dense Core Granule Neuron Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane Ribonucleoprotein Complex CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex
	Molecular Function	SNARE Binding Phosphatidylserine Binding Transporter Activity Calcium Ion Binding Clathrin Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) Binding Poly(A) RNA Binding
	Biological Process	Exocytosis Neurotransmitter Secretion Negative Regulation Of Vesicle Fusion Negative Regulation Of Calcium Ion-dependent Exocytosis	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma
Pathways
Drugs
Diseases
GWAS		Parkinson's disease ( 21738487)
Protein-Protein Interactions		10 interactors: NBR1 NRXN1 SGTA STX1A STX2 STX3 STX4 SYNCRIP SYT1 TFAP2B	31 interactors: A1CF APOBEC1 APP CSDE1 EPRS GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PRMT8 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9
Entrez ID		6860	10492
HPRD ID		02519	06734
Ensembl ID		ENSG00000132872	ENSG00000135316
Uniprot IDs		B4DEU3 Q9H2B2	B7Z645 O60506 Q59GL1
PDB IDs		1UGK	2DGU
Enriched GO Terms of Interacting Partners?		Neurotransmitter Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Vesicle Localization Vesicle Docking Membrane Docking Positive Regulation Of Synaptic Transmission Synaptic Vesicle Transport Vesicle Fusion Organelle Localization Establishment Of Vesicle Localization Secretion By Cell Organelle Fusion Synaptic Transmission Secretion Regulation Of Synaptic Transmission Establishment Of Organelle Localization Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane Membrane Fusion Cell-cell Signaling Regulation Of Insulin Secretion Vesicle Organization Regulation Of Cellular Localization Regulation Of Protein Localization To Plasma Membrane Regulation Of Peptide Hormone Secretion Positive Regulation Of Exocytosis Regulation Of Hormone Secretion Regulation Of Secretion Positive Regulation Of Protein Localization To Cell Surface Regulation Of Protein Localization Membrane Organization Regulation Of Protein Secretion Regulation Of Exocytosis Regulation Of Protein Localization To Cell Surface Protein Complex Assembly Response To Hydroperoxide Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Glutamate Secretion Regulation Of Cellular Component Organization Regulation Of Signaling Regulation Of Behavior Establishment Of Localization In Cell Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Protein Transport Cellular Protein Localization Regulation Of Establishment Of Protein Localization Regulation Of Regulated Secretory Pathway	Exocytosis MRNA Metabolic Process RNA Processing Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis MRNA Processing Cytidine To Uridine Editing Oncogene-induced Cell Senescence Secretion By Cell Positive Regulation Of Transport Senescence-associated Heterochromatin Focus Assembly Regulation Of Vesicle-mediated Transport Positive Regulation Of Cellular Senescence Regulation Of Vesicle Fusion Secretion Regulation Of Secretion RNA Metabolic Process Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of Chromatin Silencing Base Conversion Or Substitution Editing Regulation Of Cellular Localization Regulation Of Exocytosis Positive Regulation Of Cellular Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cell Aging Vesicle-mediated Transport Viral Process Positive Regulation Of Exocytosis RNA Splicing Regulation Of Growth Hormone Secretion Wound Healing Regulation Of Gene Expression Heterochromatin Assembly Positive Regulation Of Protein Metabolic Process Peptidyl-arginine N-methylation Histone H4-R3 Methylation Positive Regulation Of Metabolic Process Cellular Response To Insulin Stimulus Gene Expression Regulation Of Peptide Hormone Secretion Heterochromatin Organization Blood Coagulation Reproductive Process Hemostasis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Response To Wounding
Tagcloud ?			autonomy back bmp bottom connections correct explained genetically glass highlight influences maintaining modulates morphogenic motoneuron output partly plasticity postsynaptic presynaptic probability proper retrograde signals synapse synaptic transmission unexpected vesicle
Tagcloud (Difference) ?			autonomy back bmp bottom connections correct explained genetically glass highlight influences maintaining modulates morphogenic motoneuron output partly plasticity postsynaptic presynaptic probability proper retrograde signals synapse synaptic transmission unexpected vesicle
Tagcloud (Intersection) ?