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SYT4 and NBR1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SYT4
NBR1
Gene Name
synaptotagmin IV
neighbor of BRCA1 gene 1
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Cell Junction
Synaptic Vesicle Membrane
Dense Core Granule
Neuron Projection
Intracellular Membrane-bounded Organelle
Perinuclear Region Of Cytoplasm
Pre-autophagosomal Structure
Lysosome
Late Endosome
Autophagic Vacuole
Cytosol
Membrane
Cytoplasmic Vesicle
M Band
Extracellular Vesicular Exosome
Molecular Function
SNARE Binding
Phosphatidylserine Binding
Transporter Activity
Calcium Ion Binding
Clathrin Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Binding
Mitogen-activated Protein Kinase Binding
Biological Process
Exocytosis
Neurotransmitter Secretion
Negative Regulation Of Vesicle Fusion
Negative Regulation Of Calcium Ion-dependent Exocytosis
Macroautophagy
Regulation Of Bone Mineralization
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Osteoblast Differentiation
Protein Oligomerization
Pathways
Drugs
Diseases
GWAS
Parkinson's disease (
21738487
)
Protein-Protein Interactions
10 interactors:
NBR1
NRXN1
SGTA
STX1A
STX2
STX3
STX4
SYNCRIP
SYT1
TFAP2B
14 interactors:
ATXN1L
CALM1
CIB1
FEZ1
GABARAPL2
GSK3A
GSK3B
ITSN2
MAP1LC3A
SQSTM1
SYT4
TTN
USP8
VTA1
Entrez ID
6860
4077
HPRD ID
02519
01326
Ensembl ID
ENSG00000132872
ENSG00000188554
Uniprot IDs
B4DEU3
Q9H2B2
Q14596
PDB IDs
1UGK
1WJ6
2BKF
2CP8
2G4S
2L8J
Enriched GO Terms of Interacting Partners
?
Neurotransmitter Secretion
Synaptic Vesicle Fusion To Presynaptic Membrane
Regulation Of Neurotransmitter Levels
Synaptic Vesicle Exocytosis
Neurotransmitter Transport
Vesicle Localization
Vesicle Docking
Membrane Docking
Positive Regulation Of Synaptic Transmission
Synaptic Vesicle Transport
Vesicle Fusion
Organelle Localization
Establishment Of Vesicle Localization
Secretion By Cell
Organelle Fusion
Synaptic Transmission
Secretion
Regulation Of Synaptic Transmission
Establishment Of Organelle Localization
Exocytosis
Positive Regulation Of Protein Localization To Plasma Membrane
Membrane Fusion
Cell-cell Signaling
Regulation Of Insulin Secretion
Vesicle Organization
Regulation Of Cellular Localization
Regulation Of Protein Localization To Plasma Membrane
Regulation Of Peptide Hormone Secretion
Positive Regulation Of Exocytosis
Regulation Of Hormone Secretion
Regulation Of Secretion
Positive Regulation Of Protein Localization To Cell Surface
Regulation Of Protein Localization
Membrane Organization
Regulation Of Protein Secretion
Regulation Of Exocytosis
Regulation Of Protein Localization To Cell Surface
Protein Complex Assembly
Response To Hydroperoxide
Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane
Glutamate Secretion
Regulation Of Cellular Component Organization
Regulation Of Signaling
Regulation Of Behavior
Establishment Of Localization In Cell
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Protein Transport
Cellular Protein Localization
Regulation Of Establishment Of Protein Localization
Regulation Of Regulated Secretory Pathway
Positive Regulation Of Peptidyl-threonine Phosphorylation
Negative Regulation Of Type B Pancreatic Cell Development
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Hypermethylation Of CpG Island
Cellular Response To Interleukin-3
Regulation Of Cellular Protein Metabolic Process
Macroautophagy
Establishment Of Localization In Cell
Glycogen Metabolic Process
Negative Regulation Of Glycogen (starch) Synthase Activity
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Regulation Of Protein Metabolic Process
Polysaccharide Metabolic Process
Negative Regulation Of Cardiac Muscle Hypertrophy
Regulation Of Protein Phosphorylation
Negative Regulation Of Glycogen Biosynthetic Process
Negative Regulation Of Muscle Hypertrophy
Regulation Of Glycogen (starch) Synthase Activity
Cellular Localization
Extrinsic Apoptotic Signaling Pathway
Response To Metal Ion
Response To External Stimulus
Regulation Of Type B Pancreatic Cell Development
Positive Regulation Of Protein Phosphorylation
Apoptotic Signaling Pathway
Cellular Response To Nitrogen Starvation
Regulation Of Protein Kinase Activity
Regulation Of Phosphorylation
Regulation Of Protein Catabolic Process
Regulation Of Kinase Activity
Negative Regulation Of Transport
Energy Reserve Metabolic Process
Regulation Of DNA Methylation
Cellular Response To Starvation
Nucleophagy
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Phosphorylation
Regulation Of Intracellular Transport
Regulation Of Phosphorus Metabolic Process
Autophagy
Epidermal Growth Factor Receptor Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Gene Expression By Genetic Imprinting
Mitochondrion Degradation
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cellular Response To Stress
Tagcloud
?
abrogates
autophagy
bnip3l
carried
connections
endoplasmic
er
extent
hct116
interest
ire1
microarray
nix
p62
particular
perk
regulates
reticulum
sqstm1
stages
still
stress
subjected
transcriptional
transmembrane
unclear
unfolded
upr
upregulation
Tagcloud (Difference)
?
abrogates
autophagy
bnip3l
carried
connections
endoplasmic
er
extent
hct116
interest
ire1
microarray
nix
p62
particular
perk
regulates
reticulum
sqstm1
stages
still
stress
subjected
transcriptional
transmembrane
unclear
unfolded
upr
upregulation
Tagcloud (Intersection)
?