SYNCRIP and SYT7

Number of citations of the paper that reports this interaction (PubMedID 10734137)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, in vitro)

		SYNCRIP	SYT7
Description		synaptotagmin binding cytoplasmic RNA interacting protein	synaptotagmin 7
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Endoplasmic Reticulum Cytosol Membrane MRNA Editing Complex CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex MCRD-mediated MRNA Stability Complex Ribonucleoprotein Complex	Lysosome Lysosomal Membrane Peroxisome Peroxisomal Membrane Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Membrane Axon Transport Vesicle Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Dense Core Granule Cytoplasmic Vesicle Early Phagosome Presynaptic Membrane Cell Projection Synapse Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse Secretory Vesicle
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding MRNA 5'-UTR Binding	SNARE Binding Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Syntaxin Binding Clathrin Binding Metal Ion Binding Calcium Ion Sensor Activity
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing MRNA Processing Regulation Of Translation RNA Splicing MRNA Modification Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Type II Interferon Chromosomal 5-methylcytosine DNA Demethylation Pathway Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Positive Regulation Of Cytoplasmic Translation	Plasma Membrane Repair Exocytosis Vesicle Fusion Phagocytosis Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Endocytosis Synaptic Vesicle Recycling Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Bone Remodeling Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Phagocytosis Regulation Of Insulin Secretion Positive Regulation Of Transport Regulation Of Glucagon Secretion Vesicle-mediated Cholesterol Transport Phagosome-lysosome Fusion Calcium-dependent Activation Of Synaptic Vesicle Fusion Regulation Of Synaptic Vesicle Endocytosis Short-term Synaptic Potentiation Calcium Ion Regulated Lysosome Exocytosis
Pathways			Neurexins and neuroligins
Drugs
Diseases
GWAS			Intelligence (MTAG) ( 29326435) Mean arterial pressure ( 26390057) Metabolite levels ( 23823483) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
Interacting Genes		111 interacting genes: A1CF APOBEC1 APP CEBPA CIP2A CSDE1 EPRS1 ESR1 FNDC3B GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYPOP NUPR1 OGT PABPC1 PCSK7 PLCG1 PRMT1 PTPN11 SMN1 SUMO2 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9 TRIM55 TRIM63	8 interacting genes: AP2A1 NRXN1 SIAH1 STX1A STX2 STX3 STX4 SYNCRIP
Entrez ID		10492	9066
HPRD ID		06734	11965
Ensembl ID		ENSG00000135316	ENSG00000011347
Uniprot IDs		A0A7I2V309 A0A7I2YQN2 B7Z645 O60506 Q59GL1	O43581
PDB IDs		2DGU 2MXT 2NBB 6KOR	2D8K
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Translation RNA Destabilization Regulation Of Macromolecule Metabolic Process Positive Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Regulation Of Metabolic Process Negative Regulation Of Cytokine Production Regulation Of RNA Stability Regulation Of Angiogenesis Negative Regulation Of Cell Migration Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Locomotion Regulation Of MRNA Metabolic Process Negative Regulation Of Developmental Process Negative Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Cell Migration	SNAP Receptor Activity SNARE Complex SNARE Binding Vesicle Docking Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Neurotransmitter Transport Organelle Membrane Fusion Organelle Fusion Positive Regulation Of Synaptic Transmission Secretion By Cell Membrane Fusion Organelle Localization Exocytosis Secretion Membrane Assembly Intracellular Protein Transport Cornified Envelope Assembly Glutamatergic Synapse Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Endomembrane System Calcium-dependent Protein Binding Positive Regulation Of Protein Localization To Cell Periphery Membrane Organization Positive Regulation Of Protein Localization To Membrane Establishment Of Protein Localization Vesicle-mediated Transport In Synapse Vesicle Organization Schaffer Collateral - CA1 Synapse SNARE Complex Assembly Specific Granule Regulation Of Protein Localization To Plasma Membrane Cellular Localization Establishment Of Localization In Cell Vacuole Positive Regulation Of Protein Localization To Cell Surface Regulation Of Biological Quality Regulation Of Protein Localization To Cell Periphery Intracellular Protein Localization Modulation Of Chemical Synaptic Transmission Regulation Of Protein Localization To Membrane Presynaptic Active Zone Membrane Protein Transport Lamellipodium Positive Regulation Of Excitatory Postsynaptic Potential Vesicle-mediated Transport Intracellular Transport Synaptic Vesicle Endocytosis
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