SYNCRIP and SYT11

Number of citations of the paper that reports this interaction (PMID 10734137)
17

Data Source:
HPRD (in vitro)

		SYNCRIP	SYT11
Gene Name		synaptotagmin binding, cytoplasmic RNA interacting protein	synaptotagmin XI
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane Ribonucleoprotein Complex CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex	Integral Component Of Plasma Membrane Synaptic Vesicle Cell Junction Synaptic Vesicle Membrane
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Poly(A) Binding Poly(A) RNA Binding	Transporter Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma	Transport Negative Regulation Of Neurotransmitter Secretion
Pathways
Drugs
Diseases
GWAS			Parkinson's disease ( 21292315)
Protein-Protein Interactions		31 interactors: A1CF APOBEC1 APP CSDE1 EPRS GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PRMT8 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9	4 interactors: APPBP2 PARK2 SGTA SYNCRIP
Entrez ID		10492	23208
HPRD ID		06734	12289
Ensembl ID		ENSG00000135316	ENSG00000132718
Uniprot IDs		B7Z645 O60506 Q59GL1	Q9BT88
PDB IDs		2DGU
Enriched GO Terms of Interacting Partners?		Exocytosis MRNA Metabolic Process RNA Processing Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis MRNA Processing Cytidine To Uridine Editing Oncogene-induced Cell Senescence Secretion By Cell Positive Regulation Of Transport Senescence-associated Heterochromatin Focus Assembly Regulation Of Vesicle-mediated Transport Positive Regulation Of Cellular Senescence Regulation Of Vesicle Fusion Secretion Regulation Of Secretion RNA Metabolic Process Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of Chromatin Silencing Base Conversion Or Substitution Editing Regulation Of Cellular Localization Regulation Of Exocytosis Positive Regulation Of Cellular Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cell Aging Vesicle-mediated Transport Viral Process Positive Regulation Of Exocytosis RNA Splicing Regulation Of Growth Hormone Secretion Wound Healing Regulation Of Gene Expression Heterochromatin Assembly Positive Regulation Of Protein Metabolic Process Peptidyl-arginine N-methylation Histone H4-R3 Methylation Positive Regulation Of Metabolic Process Cellular Response To Insulin Stimulus Gene Expression Regulation Of Peptide Hormone Secretion Heterochromatin Organization Blood Coagulation Reproductive Process Hemostasis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Response To Wounding	Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Positive Regulation Of Protein Linear Polyubiquitination Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Manganese Ion CRD-mediated MRNA Stabilization Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Negative Regulation Of Mitochondrial Fusion Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Fusion Negative Regulation Of Glucokinase Activity Neuron Cellular Homeostasis Positive Regulation Of Oxidative Stress-induced Cell Death Protein K6-linked Ubiquitination Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Mitochondrial Fission Regulation Of Mitochondrion Degradation Dopamine Transport Aggresome Assembly Regulation Of Mitochondrial Fission Neurotransmitter Uptake Norepinephrine Metabolic Process Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Actin Filament Bundle Assembly Synaptic Transmission, Dopaminergic Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Zinc Ion Homeostasis Negative Regulation Of Release Of Cytochrome C From Mitochondria Response To Manganese Ion Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Viral Process Cellular Response To Ammonium Ion Regulation Of Dopamine Secretion Cellular Response To Toxic Substance Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Monoamine Transport Mitochondrial Fission MRNA Stabilization Cellular Response To Catecholamine Stimulus Negative Regulation Of Oxidative Stress-induced Cell Death Startle Response Mitochondrion Degradation Dopamine Metabolic Process Positive Regulation Of Cytokine-mediated Signaling Pathway
Tagcloud ?		autonomy back bmp bottom connections correct explained genetically glass highlight influences maintaining modulates morphogenic motoneuron output partly plasticity postsynaptic presynaptic probability proper retrograde signals synapse synaptic transmission unexpected vesicle	ago2 assigned c2 c2a c2b calcium constituting fmrp golgi insensitive interacted isoforms link micrornas partners q repeats risc silencing snare snd snd1 synaptotagmin synaptotagmins tandem traffic transmembrane vesicles vti1a
Tagcloud (Difference) ?		autonomy back bmp bottom connections correct explained genetically glass highlight influences maintaining modulates morphogenic motoneuron output partly plasticity postsynaptic presynaptic probability proper retrograde signals synapse synaptic transmission unexpected vesicle	ago2 assigned c2 c2a c2b calcium constituting fmrp golgi insensitive interacted isoforms link micrornas partners q repeats risc silencing snare snd snd1 synaptotagmin synaptotagmins tandem traffic transmembrane vesicles vti1a
Tagcloud (Intersection) ?