SULT1C2 and ACD

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		SULT1C2	ACD
Gene Name		sulfotransferase family, cytosolic, 1C, member 2	adrenocortical dysplasia homolog (mouse)
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Sulfotransferase Activity	DNA Binding Protein Binding DNA Polymerase Binding
	Biological Process	Xenobiotic Metabolic Process Amine Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Segmentation Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Cytosolic sulfonation of small molecules Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ACD HLTF POT1 RASGRP3 TERF1 TINF2	59 interactors: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790
Entrez ID		6819	65057
HPRD ID		03858	12417
Ensembl ID		ENSG00000198203	ENSG00000102977
Uniprot IDs		B4DLP0 O00338	Q96AP0
PDB IDs		3BFX	2I46
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Replication Telomere Maintenance Negative Regulation Of Chromosome Organization Regulation Of Telomerase Activity Negative Regulation Of DNA Metabolic Process Regulation Of DNA Replication Telomere Maintenance Via Telomere Lengthening Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Telomere Capping Protein Localization To Chromosome, Telomeric Region Chromosome Organization Positive Regulation Of Telomerase Activity DNA Metabolic Process Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Metabolic Process Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome Regulation Of Organelle Organization Positive Regulation Of Organelle Organization Positive Regulation Of DNA Replication Negative Regulation Of Biosynthetic Process Homeostatic Process Organelle Organization Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Regulation Of Protein ADP-ribosylation Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cellular Component Assembly Regulation Of Cellular Component Organization Telomeric Loop Formation Telomere Formation Via Telomerase Age-dependent Telomere Shortening Negative Regulation Of Cellular Metabolic Process Telomere Maintenance Via Telomere Shortening Negative Regulation Of Protein Glycosylation Regulation Of Metabolic Process Protection From Non-homologous End Joining At Telomere Regulation Of Catalytic Activity Nucleobase-containing Compound Metabolic Process	Organelle Organization Protein Folding Carbohydrate Catabolic Process Substantia Nigra Development Neural Nucleus Development 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Nervous System Development Catabolic Process Cellular Component Assembly Midbrain Development Glycolytic Process Multicellular Organismal Development Negative Regulation Of Telomere Maintenance Via Telomerase Generation Of Neurons Telomere Assembly Pyruvate Metabolic Process Neurogenesis Developmental Process Negative Regulation Of Telomere Maintenance Monosaccharide Metabolic Process Regulation Of Cellular Protein Metabolic Process Brain Development Cellular Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Head Development Glucose Metabolic Process Neuron Projection Development Neuron Projection Morphogenesis Telomere Maintenance Cell Differentiation Neuron Differentiation Regulation Of Protein Metabolic Process System Development DNA Duplex Unwinding DNA Geometric Change Regulation Of Telomere Maintenance Cellular Process Neuron Development Adherens Junction Organization Central Nervous System Development Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Negative Regulation Of DNA Metabolic Process Protein Polymerization Regulation Of Signaling Innate Immune Response DNA Metabolic Process
Tagcloud ?			acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86
Tagcloud (Difference) ?			acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86
Tagcloud (Intersection) ?