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SULT1C2 and HLTF
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SULT1C2
HLTF
Gene Name
sulfotransferase family, cytosolic, 1C, member 2
helicase-like transcription factor
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Membrane
Molecular Function
Sulfotransferase Activity
DNA Binding
Helicase Activity
Protein Binding
ATP Binding
Zinc Ion Binding
Ligase Activity
ATPase Activity
Poly(A) RNA Binding
Ubiquitin Protein Ligase Activity
Biological Process
Xenobiotic Metabolic Process
Amine Metabolic Process
Small Molecule Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Sulfation
Protein Polyubiquitination
Postreplication Repair
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Modification
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective UGT1A4 causes hyperbilirubinemia
Metabolic disorders of biological oxidation enzymes
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Cytosolic sulfonation of small molecules
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
ACD
HLTF
POT1
RASGRP3
TERF1
TINF2
14 interactors:
CDK9
EEF1G
EWSR1
HSPA8
PCNA
SP1
SP3
SULT1C2
UBC
UBE2A
UBE2N
UBE2V2
UBE2Z
WBP4
Entrez ID
6819
6596
HPRD ID
03858
04461
Ensembl ID
ENSG00000198203
ENSG00000071794
Uniprot IDs
B4DLP0
O00338
Q05BZ6
Q14527
PDB IDs
3BFX
2L1I
4HRE
4HRH
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Telomere Assembly
Negative Regulation Of DNA Replication
Telomere Maintenance
Negative Regulation Of Chromosome Organization
Regulation Of Telomerase Activity
Negative Regulation Of DNA Metabolic Process
Regulation Of DNA Replication
Telomere Maintenance Via Telomere Lengthening
Regulation Of Chromosome Organization
Regulation Of DNA Biosynthetic Process
Telomere Capping
Protein Localization To Chromosome, Telomeric Region
Chromosome Organization
Positive Regulation Of Telomerase Activity
DNA Metabolic Process
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance
Positive Regulation Of DNA Metabolic Process
Positive Regulation Of DNA Biosynthetic Process
RNA-dependent DNA Replication
Negative Regulation Of DNA Biosynthetic Process
Protein Localization To Chromosome
Regulation Of Organelle Organization
Positive Regulation Of Organelle Organization
Positive Regulation Of DNA Replication
Negative Regulation Of Biosynthetic Process
Homeostatic Process
Organelle Organization
Negative Regulation Of Protein ADP-ribosylation
Positive Regulation Of Single-stranded Telomeric DNA Binding
Positive Regulation Of DNA Strand Elongation
Regulation Of Protein ADP-ribosylation
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Cellular Component Assembly
Regulation Of Cellular Component Organization
Telomeric Loop Formation
Telomere Formation Via Telomerase
Age-dependent Telomere Shortening
Negative Regulation Of Cellular Metabolic Process
Telomere Maintenance Via Telomere Shortening
Negative Regulation Of Protein Glycosylation
Regulation Of Metabolic Process
Protection From Non-homologous End Joining At Telomere
Regulation Of Catalytic Activity
Nucleobase-containing Compound Metabolic Process
Postreplication Repair
Protein Polyubiquitination
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
DNA Repair
Nitrogen Compound Metabolic Process
Cellular Response To DNA Damage Stimulus
Regulation Of DNA Repair
Cellular Metabolic Process
DNA Double-strand Break Processing
Cellular Response To Stress
Protein Ubiquitination
Embryonic Process Involved In Female Pregnancy
DNA Metabolic Process
Protein Modification By Small Protein Conjugation
Enucleate Erythrocyte Differentiation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Response To DNA Damage Stimulus
Megakaryocyte Differentiation
Transforming Growth Factor Beta Receptor Signaling Pathway
Definitive Hemopoiesis
Positive Regulation Of DNA Metabolic Process
Trophectodermal Cell Differentiation
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Transcription Initiation From RNA Polymerase II Promoter
RNA Metabolic Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Protein K63-linked Ubiquitination
Response To Transforming Growth Factor Beta
DNA Catabolic Process, Exonucleolytic
Positive Regulation Of DNA Repair
Histone Ubiquitination
Positive Regulation Of Metabolic Process
Viral Process
Blastocyst Formation
Embryonic Camera-type Eye Morphogenesis
Gene Expression
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
DNA-templated Transcription, Initiation
Embryonic Eye Morphogenesis
Female Pregnancy
Positive Regulation Of Viral Transcription
Cellular Macromolecule Biosynthetic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Macromolecule Biosynthetic Process
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Tagcloud
?
672e
aside
attenuates
bambi
bmp5
brains
cflar
cohesion
condensation
disrupts
encephalomalacia
exons
metacore
null
participates
postpartum
rad21
rad5
scc1
scgb3a1
seq
smad7
smc2
snapshot
tnfrsf6
transcriptome
triggering
unidentified
wnt10b
Tagcloud (Difference)
?
672e
aside
attenuates
bambi
bmp5
brains
cflar
cohesion
condensation
disrupts
encephalomalacia
exons
metacore
null
participates
postpartum
rad21
rad5
scc1
scgb3a1
seq
smad7
smc2
snapshot
tnfrsf6
transcriptome
triggering
unidentified
wnt10b
Tagcloud (Intersection)
?