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SULT1C2 and TERF1
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
SULT1C2
TERF1
Gene Name
sulfotransferase family, cytosolic, 1C, member 2
telomeric repeat binding factor (NIMA-interacting) 1
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Extracellular Vesicular Exosome
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nuclear Chromosome, Telomeric Region
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Spindle
Molecular Function
Sulfotransferase Activity
DNA Binding
Chromatin Binding
Double-stranded Telomeric DNA Binding
Protein Binding
Microtubule Binding
DNA Binding, Bending
Telomeric DNA Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Biological Process
Xenobiotic Metabolic Process
Amine Metabolic Process
Small Molecule Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Sulfation
G2/M Transition Of Mitotic Cell Cycle
Telomere Maintenance
Age-dependent Telomere Shortening
Telomere Maintenance Via Telomerase
Mitotic Nuclear Division
Mitotic Spindle Assembly Checkpoint
Negative Regulation Of DNA Replication
Positive Regulation Of Microtubule Polymerization
Telomeric Loop Formation
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Response To Drug
Positive Regulation Of Apoptotic Process
Positive Regulation Of Mitotic Nuclear Division
Positive Regulation Of Mitotic Cell Cycle
Protein Homooligomerization
Cell Division
Negative Regulation Of Telomerase Activity
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective UGT1A4 causes hyperbilirubinemia
Metabolic disorders of biological oxidation enzymes
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Cytosolic sulfonation of small molecules
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Drugs
Diseases
GWAS
Crohn's disease (
22412388
)
Protein-Protein Interactions
6 interactors:
ACD
HLTF
POT1
RASGRP3
TERF1
TINF2
200 interactors:
ACAT2
ACOT7
ACY1
AFAP1L2
AHCY
AK1
AKR1A1
ALDOA
AMPD2
AMPH
ANXA2
ANXA5
APEX1
ARHGDIA
ARPP21
ASS1
ATM
BCL7B
BIN2
BLM
BRAF
C12orf43
C19orf66
C1orf35
CALD1
CAPNS1
CASP7
CCDC9
CDC6
CEP85
CFL1
CKB
CORO1B
CPNE3
CRYBB1
CRYM
DBN1
DBNL
DCX
DDX19B
DDX21
DDX23
DDX24
DDX39A
DLG5
DNAJB1
DNPH1
DPP3
DPYSL3
EEF1D
EIF4B
ENO2
EPB41L1
EPHX2
EVL
FANCD2
FBP1
FBXO4
FEN1
FES
FKBP8
GAMT
GAPDH
GIT1
GNL3L
GNMT
GSS
HCLS1
HDGFRP2
HEXIM1
HEXIM2
HGD
HIST1H1A
HMGN3
HMGN4
HMOX1
HNMT
HOXA3
HSP90AB1
HSPA6
IPO5
JSRP1
KDM1A
KEAP1
KIAA1279
KLHDC4
KPNB1
LASP1
LDHA
LDHB
LRSAM1
LYAR
MAP4
MAP7
MAPK12
MAPRE1
MCM2
MDH1
MSN
MT1X
MVK
NAP1L1
NBN
NEFL
NME1
NME2
NOL12
NOL3
NUDCD2
NUDT14
NUMA1
NXNL1
OCM2
OGFR
PA2G4
PACSIN2
PAFAH1B3
PAGE2
PAICS
PAK4
PCP4
PEPD
PFKP
PFN2
PGD
PGLS
PGM1
PGM2
PINX1
PKM
PNMT
POT1
PPM1G
PRDX1
PRDX6
PRKCB
PTMA
PTPN5
RBMY1A1
RECQL4
RIC8A
RLIM
RNF10
RPAP3
RPL19
RTN3
RTN4
SALL1
SARS
SBDS
SET
SH3BP1
SH3GL2
SH3GL3
SIRPD
SKP1
SMAD9
SMARCC2
SNCG
SOAT1
SP100
SRM
SRSF6
STUB1
SULT1C2
SUPT5H
SYK
TALDO1
TBC1D10A
TBCD
TBL1X
TCIRG1
TERT
THG1L
TINAG
TINF2
TKT
TMSB10
TMSB4Y
TNKS
TNKS2
TNPO2
TOMM34
TPI1
TRIM16
TRIP10
TRMT1
TUBB2A
TUBB3
TUBB4B
UTP14A
WARS
WDR4
WFS1
YWHAG
ZBTB16
ZC3H18
ZFP36L1
ZHX1
ZNF790
Entrez ID
6819
7013
HPRD ID
03858
02975
Ensembl ID
ENSG00000198203
ENSG00000147601
Uniprot IDs
B4DLP0
O00338
P54274
PDB IDs
3BFX
1BA5
1H6O
1ITY
1IV6
1W0T
3BQO
3L82
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Telomere Assembly
Negative Regulation Of DNA Replication
Telomere Maintenance
Negative Regulation Of Chromosome Organization
Regulation Of Telomerase Activity
Negative Regulation Of DNA Metabolic Process
Regulation Of DNA Replication
Telomere Maintenance Via Telomere Lengthening
Regulation Of Chromosome Organization
Regulation Of DNA Biosynthetic Process
Telomere Capping
Protein Localization To Chromosome, Telomeric Region
Chromosome Organization
Positive Regulation Of Telomerase Activity
DNA Metabolic Process
Negative Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Positive Regulation Of Telomere Maintenance
Positive Regulation Of DNA Metabolic Process
Positive Regulation Of DNA Biosynthetic Process
RNA-dependent DNA Replication
Negative Regulation Of DNA Biosynthetic Process
Protein Localization To Chromosome
Regulation Of Organelle Organization
Positive Regulation Of Organelle Organization
Positive Regulation Of DNA Replication
Negative Regulation Of Biosynthetic Process
Homeostatic Process
Organelle Organization
Negative Regulation Of Protein ADP-ribosylation
Positive Regulation Of Single-stranded Telomeric DNA Binding
Positive Regulation Of DNA Strand Elongation
Regulation Of Protein ADP-ribosylation
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Cellular Component Assembly
Regulation Of Cellular Component Organization
Telomeric Loop Formation
Telomere Formation Via Telomerase
Age-dependent Telomere Shortening
Negative Regulation Of Cellular Metabolic Process
Telomere Maintenance Via Telomere Shortening
Negative Regulation Of Protein Glycosylation
Regulation Of Metabolic Process
Protection From Non-homologous End Joining At Telomere
Regulation Of Catalytic Activity
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Aromatic Compound Metabolic Process
Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Cellular Metabolic Process
Organelle Organization
Heterocycle Metabolic Process
Telomere Maintenance
Catabolic Process
Small Molecule Metabolic Process
Cellular Process
Pathogenesis
Carbohydrate Biosynthetic Process
Monosaccharide Metabolic Process
Regulation Of Cellular Component Organization
Glucose Metabolic Process
Carboxylic Acid Metabolic Process
Chromosome Organization
Biosynthetic Process
Organic Acid Metabolic Process
Carbohydrate Catabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Glycolytic Process
Ribose Phosphate Metabolic Process
Pyruvate Metabolic Process
Telomere Maintenance Via Telomere Lengthening
Cellular Component Assembly
Protein Complex Assembly
Positive Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Gluconeogenesis
Pentose-phosphate Shunt
Glyceraldehyde-3-phosphate Metabolic Process
Hexose Metabolic Process
Positive Regulation Of Telomere Maintenance Via Telomerase
Organophosphate Metabolic Process
Hexose Biosynthetic Process
Cell Cycle Process
Mitotic Cell Cycle
Metabolic Process
Nucleotide Metabolic Process
Regulation Of Organelle Organization
Nicotinamide Nucleotide Metabolic Process
Pentose Biosynthetic Process
Glucose 6-phosphate Metabolic Process
Response To Organic Substance
Regulation Of Telomere Maintenance
Regulation Of DNA Replication
NADP Metabolic Process
Aromatic Compound Catabolic Process
Tagcloud
?
anticancer
catalytic
cloned
compensate
division
elucidated
encoding
erosion
fusions
generally
homolog
immortality
length
neoplasms
p80
protection
repeat
repeats
repressed
ribonucleoprotein
telomerase
telomere
telomeric
tep1
terc
terf2
tert
upregulated
withdrawal
Tagcloud (Difference)
?
anticancer
catalytic
cloned
compensate
division
elucidated
encoding
erosion
fusions
generally
homolog
immortality
length
neoplasms
p80
protection
repeat
repeats
repressed
ribonucleoprotein
telomerase
telomere
telomeric
tep1
terc
terf2
tert
upregulated
withdrawal
Tagcloud (Intersection)
?