AURKA and IKBKB

  • Number of citations of the paper that reports this interaction (PMID 17939994)
  • 19
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study)

AURKA

IKBKB

Gene Name aurora kinase A inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 54 interactors: APP ARPC1B ARPC2 AURKAIP1 BIRC5 BORA BRCA1 CBX3 CDC20 CDC25B CHFR CKAP5 CSN2 GADD45A GMNN GSK3B HDAC2 HDAC6 HIST3H3 IKBKB INCENP KIF11 KIF2C MAPRE2 MAPRE3 MBD3 MDM2 NDC80 NFKBIA NIN NME1 NUF2 PLK3 PML PPP1CA PPP1CB PPP1CC PRKACA PTTG1 PUM2 RASSF1 SRPK1 SRPK2 SUMO1 TACC1 TACC3 TLK1 TLK2 TP53 TP73 TPX2 UBE2N USP2 VHL 78 interactors: ACVR1 AKT1 AURKA BCL10 CASP8 CCAR2 CDC37 CFLAR CHUK COPS3 COPS4 CSF2RA CSF2RB CTNNB1 CUEDC2 EIF2AK2 EIF2AK3 FAF1 FANCA FOXO3 HSP90AA1 HSP90AB1 HTT IKBKAP IKBKG IRS1 JUN MAP3K1 MAP3K11 MAP3K13 MAP3K14 MAP3K3 MAP3K7 NAA20 NCOA3 NEDD4L NFKB1 NFKB2 NFKBIA NFKBIB NR2C2 PEBP1 PELI1 PLK1 PPARG PPM1B PPP2R3C PRKCA PRKCB PRKCD PRKCE PRKCQ PRKCZ PRKDC RELA RICTOR RIPK1 ROCK1 SRC STAP2 TAB2 TANK TBK1 TFAP2C TGFBR1 TNFAIP3 TNFRSF1A TP53 TP73 TRAF1 TRAF2 TRAF3IP2 TRIM21 TRIM27 TRPC4AP TSC1 UBB YWHAB
Entrez ID 6790 3551
HPRD ID 04066 04462
Ensembl ID ENSG00000087586 ENSG00000104365
Uniprot IDs O14965 O14920
PDB IDs 1MQ4 1MUO 1OL5 1OL6 1OL7 2BMC 2C6D 2C6E 2DWB 2J4Z 2J50 2NP8 2W1C 2W1D 2W1E 2W1F 2W1G 2WQE 2WTV 2WTW 2X6D 2X6E 2X81 2XNE 2XNG 2XRU 3COH 3E5A 3EFW 3FDN 3H0Y 3H0Z 3H10 3HA6 3K5U 3LAU 3M11 3MYG 3NRM 3O50 3O51 3P9J 3QBN 3R21 3R22 3UNZ 3UO4 3UO5 3UO6 3UOD 3UOH 3UOJ 3UOK 3UOL 3UP2 3UP7 3VAP 4B0G 4DEA 4DEB 4DED 4DEE 4DHF 4JAI 4JAJ 4JBO 4JBP 4JBQ 3BRT 3BRV 4E3C 4KIK
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenosine  ags  alisertib  als  ampk  antiapoptotic  aurora  autophagy  bioavailable  cip1  cytochrome  dependently  exerts  inducing  killing  kip1  mitochondria  monophosphate  n78  nci  orally  phosphatidylinositol  proapoptotic  proautophagic  responds  sb202191  threonine  waf1  wortmannin 
abi  analyse  ctla4  episodes  genotyped  il4ra  il8  map3k1  mbl2  nfkbia  nfkbib  polymorphisms  prism  recurrent  rhinovirus  rs1800450ct  rs1801275gg  rs2146323aa  rs2233419ag  rs3087243ag  rs3136641tt  rs3747811at  rs3775291tc  rs4073at  rs702689aa  rs833058ct  tlr3  vegfa  wheezing 
Tagcloud (Difference) ?
adenosine  ags  alisertib  als  ampk  antiapoptotic  aurora  autophagy  bioavailable  cip1  cytochrome  dependently  exerts  inducing  killing  kip1  mitochondria  monophosphate  n78  nci  orally  phosphatidylinositol  proapoptotic  proautophagic  responds  sb202191  threonine  waf1  wortmannin 
abi  analyse  ctla4  episodes  genotyped  il4ra  il8  map3k1  mbl2  nfkbia  nfkbib  polymorphisms  prism  recurrent  rhinovirus  rs1800450ct  rs1801275gg  rs2146323aa  rs2233419ag  rs3087243ag  rs3136641tt  rs3747811at  rs3775291tc  rs4073at  rs702689aa  rs833058ct  tlr3  vegfa  wheezing 
Tagcloud (Intersection) ?