IKBKB and IRS1

  • Number of citations of the paper that reports this interaction (PMID 10722755)
  • 247
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

IKBKB

IRS1

Gene Name inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta insulin receptor substrate 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 78 interactors: ACVR1 AKT1 AURKA BCL10 CASP8 CCAR2 CDC37 CFLAR CHUK COPS3 COPS4 CSF2RA CSF2RB CTNNB1 CUEDC2 EIF2AK2 EIF2AK3 FAF1 FANCA FOXO3 HSP90AA1 HSP90AB1 HTT IKBKAP IKBKG IRS1 JUN MAP3K1 MAP3K11 MAP3K13 MAP3K14 MAP3K3 MAP3K7 NAA20 NCOA3 NEDD4L NFKB1 NFKB2 NFKBIA NFKBIB NR2C2 PEBP1 PELI1 PLK1 PPARG PPM1B PPP2R3C PRKCA PRKCB PRKCD PRKCE PRKCQ PRKCZ PRKDC RELA RICTOR RIPK1 ROCK1 SRC STAP2 TAB2 TANK TBK1 TFAP2C TGFBR1 TNFAIP3 TNFRSF1A TP53 TP73 TRAF1 TRAF2 TRAF3IP2 TRIM21 TRIM27 TRPC4AP TSC1 UBB YWHAB 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ
Entrez ID 3551 3667
HPRD ID 04462 00943
Ensembl ID ENSG00000104365 ENSG00000169047
Uniprot IDs O14920 P35568
PDB IDs 3BRT 3BRV 4E3C 4KIK 1IRS 1K3A 1QQG 2Z8C
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abi  analyse  ctla4  episodes  genotyped  il4ra  il8  map3k1  mbl2  nfkbia  nfkbib  polymorphisms  prism  recurrent  rhinovirus  rs1800450ct  rs1801275gg  rs2146323aa  rs2233419ag  rs3087243ag  rs3136641tt  rs3747811at  rs3775291tc  rs4073at  rs702689aa  rs833058ct  tlr3  vegfa  wheezing 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Difference) ?
abi  analyse  ctla4  episodes  genotyped  il4ra  il8  map3k1  mbl2  nfkbia  nfkbib  polymorphisms  prism  recurrent  rhinovirus  rs1800450ct  rs1801275gg  rs2146323aa  rs2233419ag  rs3087243ag  rs3136641tt  rs3747811at  rs3775291tc  rs4073at  rs702689aa  rs833058ct  tlr3  vegfa  wheezing 
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
Tagcloud (Intersection) ?