AURKA and PPP1CC

  • Number of citations of the paper that reports this interaction (PMID 11551964)
  • 39
  • Data Source:
  • BioGRID (enzymatic study, enzymatic study)
  • HPRD (in vivo, in vitro)

AURKA

PPP1CC

Gene Name aurora kinase A protein phosphatase 1, catalytic subunit, gamma isozyme
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 54 interactors: APP ARPC1B ARPC2 AURKAIP1 BIRC5 BORA BRCA1 CBX3 CDC20 CDC25B CHFR CKAP5 CSN2 GADD45A GMNN GSK3B HDAC2 HDAC6 HIST3H3 IKBKB INCENP KIF11 KIF2C MAPRE2 MAPRE3 MBD3 MDM2 NDC80 NFKBIA NIN NME1 NUF2 PLK3 PML PPP1CA PPP1CB PPP1CC PRKACA PTTG1 PUM2 RASSF1 SRPK1 SRPK2 SUMO1 TACC1 TACC3 TLK1 TLK2 TP53 TP73 TPX2 UBE2N USP2 VHL 114 interactors: AATK ABT1 ACAD8 AKAP11 ANKRD42 APIP APP ASH2L AURKA B4GAT1 BMPR2 BTBD10 C11orf74 C15orf59 C1QA C9orf50 CD2BP2 CLMN CLTC CNST COPS5 CSNK1A1 CSRNP1 CSRNP2 CTSL CYFIP1 DACT1 DEAF1 DYRK4 EIF2AK2 ELP4 ENKD1 FTL FXYD6 GLB1L GOLGA7 GSTZ1 HCFC1 HDAC6 HMGN1 IL3RA JAK2 KCTD20 KDM4D KIAA1377 KRCC1 LMTK2 MAP4K4 MYO16 NAPEPLD NEK2 NMT2 NONO NRBP1 NUAK1 PHACTR4 PHC1 PIAS1 PPP1R13B PPP1R15B PPP1R16A PPP1R18 PPP1R2 PPP1R32 PPP1R35 PPP1R3C PPP1R3D PPP1R8 PPP1R9B PRR16 RAF1 RB1 RIF1 RNF19B RPL7 RPRD2 RRM1 RRP1B SDR39U1 SGCE SH3RF2 SHANK3 SMARCB1 SMG6 SPATC1L SPOCD1 STAM STARD9 STAU1 TACC2 TBC1D19 TCTEX1D4 TEFM TEX36 TLX1 TLX3 TMEM120A TNS1 TOPBP1 TOR1AIP1 TP53 TP53BP2 TPRN TRA2A TWISTNB VSTM4 WBP11 YLPM1 YWHAZ ZDBF2 ZFYVE9 ZNF24 ZNF318 ZNF667
Entrez ID 6790 5501
HPRD ID 04066 08911
Ensembl ID ENSG00000087586 ENSG00000186298
Uniprot IDs O14965 P36873
PDB IDs 1MQ4 1MUO 1OL5 1OL6 1OL7 2BMC 2C6D 2C6E 2DWB 2J4Z 2J50 2NP8 2W1C 2W1D 2W1E 2W1F 2W1G 2WQE 2WTV 2WTW 2X6D 2X6E 2X81 2XNE 2XNG 2XRU 3COH 3E5A 3EFW 3FDN 3H0Y 3H0Z 3H10 3HA6 3K5U 3LAU 3M11 3MYG 3NRM 3O50 3O51 3P9J 3QBN 3R21 3R22 3UNZ 3UO4 3UO5 3UO6 3UOD 3UOH 3UOJ 3UOK 3UOL 3UP2 3UP7 3VAP 4B0G 4DEA 4DEB 4DED 4DEE 4DHF 4JAI 4JAJ 4JBO 4JBP 4JBQ 1IT6 1JK7 1U32 2BCD 2BDX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenosine  ags  alisertib  als  ampk  antiapoptotic  aurora  autophagy  bioavailable  cip1  cytochrome  dependently  exerts  inducing  killing  kip1  mitochondria  monophosphate  n78  nci  orally  phosphatidylinositol  proapoptotic  proautophagic  responds  sb202191  threonine  waf1  wortmannin 
3xflag  atp5c1  compatible  created  creating  ddost  deleted  dissociated  envelope  immunolocalization  knock  mammals  persists  phosphatases  reciprocal  sbp  sedimentation  spermatogenesis  spermatogenic  splice  tagged  tandem  testis  ubiquitously 
Tagcloud (Difference) ?
adenosine  ags  alisertib  als  ampk  antiapoptotic  aurora  autophagy  bioavailable  cip1  cytochrome  dependently  exerts  inducing  killing  kip1  mitochondria  monophosphate  n78  nci  orally  phosphatidylinositol  proapoptotic  proautophagic  responds  sb202191  threonine  waf1  wortmannin 
3xflag  atp5c1  compatible  created  creating  ddost  deleted  dissociated  envelope  immunolocalization  knock  mammals  persists  phosphatases  reciprocal  sbp  sedimentation  spermatogenesis  spermatogenic  splice  tagged  tandem  testis  ubiquitously 
Tagcloud (Intersection) ?