AURKA and BIRC5

  • Number of citations of the paper that reports this interaction (PMID 19357306)
  • 9
  • Data Source:
  • BioGRID (enzymatic study)

AURKA

BIRC5

Gene Name aurora kinase A baculoviral IAP repeat containing 5
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood trace element (Se levels) ( 23720494)
Protein-Protein Interactions 54 interactors: APP ARPC1B ARPC2 AURKAIP1 BIRC5 BORA BRCA1 CBX3 CDC20 CDC25B CHFR CKAP5 CSN2 GADD45A GMNN GSK3B HDAC2 HDAC6 HIST3H3 IKBKB INCENP KIF11 KIF2C MAPRE2 MAPRE3 MBD3 MDM2 NDC80 NFKBIA NIN NME1 NUF2 PLK3 PML PPP1CA PPP1CB PPP1CC PRKACA PTTG1 PUM2 RASSF1 SRPK1 SRPK2 SUMO1 TACC1 TACC3 TLK1 TLK2 TP53 TP73 TPX2 UBE2N USP2 VHL 22 interactors: AURKA AURKB AURKC BIRC2 BIRC3 BIRC6 CASP3 CASP7 CASP9 CDCA8 CDK1 CDK4 DIABLO EVI5 HIST2H3C HIST3H3 HSP90AA1 INCENP KCNJ6 RASA1 XIAP XPO1
Entrez ID 6790 332
HPRD ID 04066 04520
Ensembl ID ENSG00000087586 ENSG00000089685
Uniprot IDs O14965 H3BLT4 O15392
PDB IDs 1MQ4 1MUO 1OL5 1OL6 1OL7 2BMC 2C6D 2C6E 2DWB 2J4Z 2J50 2NP8 2W1C 2W1D 2W1E 2W1F 2W1G 2WQE 2WTV 2WTW 2X6D 2X6E 2X81 2XNE 2XNG 2XRU 3COH 3E5A 3EFW 3FDN 3H0Y 3H0Z 3H10 3HA6 3K5U 3LAU 3M11 3MYG 3NRM 3O50 3O51 3P9J 3QBN 3R21 3R22 3UNZ 3UO4 3UO5 3UO6 3UOD 3UOH 3UOJ 3UOK 3UOL 3UP2 3UP7 3VAP 4B0G 4DEA 4DEB 4DED 4DEE 4DHF 4JAI 4JAJ 4JBO 4JBP 4JBQ 1E31 1F3H 1XOX 2QFA 2RAW 2RAX 3UEC 3UED 3UEE 3UEF 3UEG 3UEH 3UEI 3UIG 3UIH 3UII 3UIJ 3UIK 4A0I 4A0J 4A0N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenosine  ags  alisertib  als  ampk  antiapoptotic  aurora  autophagy  bioavailable  cip1  cytochrome  dependently  exerts  inducing  killing  kip1  mitochondria  monophosphate  n78  nci  orally  phosphatidylinositol  proapoptotic  proautophagic  responds  sb202191  threonine  waf1  wortmannin 
autophagy  bcl2  buffer  constituents  damaged  dataset  degrades  deregulation  distant  eif4ebp1  ero1l  fos  gapdh  gse21653  gse3494  gse7390  inc  itpr1  lived  organelles  periodicals  prognostic  proportional  shortened  signature  starvation  subgroups  vegfa  wiley 
Tagcloud (Difference) ?
adenosine  ags  alisertib  als  ampk  antiapoptotic  aurora  bioavailable  cip1  cytochrome  dependently  exerts  inducing  killing  kip1  mitochondria  monophosphate  n78  nci  orally  phosphatidylinositol  proapoptotic  proautophagic  responds  sb202191  threonine  waf1  wortmannin 
bcl2  buffer  constituents  damaged  dataset  degrades  deregulation  distant  eif4ebp1  ero1l  fos  gapdh  gse21653  gse3494  gse7390  inc  itpr1  lived  organelles  periodicals  prognostic  proportional  shortened  signature  starvation  subgroups  vegfa  wiley 
Tagcloud (Intersection) ?
autophagy