IKBKB and NEDD4L

  • Number of citations of the paper that reports this interaction (PMID 18981174)
  • 13
  • Data Source:
  • BioGRID (enzymatic study)

IKBKB

NEDD4L

Gene Name inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Insomnia (caffeine-induced) ( 22754043)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 22001757)
  • Response to amphetamines ( 22952603)
Protein-Protein Interactions 78 interactors: ACVR1 AKT1 AURKA BCL10 CASP8 CCAR2 CDC37 CFLAR CHUK COPS3 COPS4 CSF2RA CSF2RB CTNNB1 CUEDC2 EIF2AK2 EIF2AK3 FAF1 FANCA FOXO3 HSP90AA1 HSP90AB1 HTT IKBKAP IKBKG IRS1 JUN MAP3K1 MAP3K11 MAP3K13 MAP3K14 MAP3K3 MAP3K7 NAA20 NCOA3 NEDD4L NFKB1 NFKB2 NFKBIA NFKBIB NR2C2 PEBP1 PELI1 PLK1 PPARG PPM1B PPP2R3C PRKCA PRKCB PRKCD PRKCE PRKCQ PRKCZ PRKDC RELA RICTOR RIPK1 ROCK1 SRC STAP2 TAB2 TANK TBK1 TFAP2C TGFBR1 TNFAIP3 TNFRSF1A TP53 TP73 TRAF1 TRAF2 TRAF3IP2 TRIM21 TRIM27 TRPC4AP TSC1 UBB YWHAB 126 interactors: AATF ABL1 ABL2 ACVR1B ACY3 ADAP2 AICDA AKT3 APEX2 ARHGDIA AURKC BBX BMPR1A BRAF C7orf50 CACNB1 CAMK1D CDC34 CDK3 CDK5 CLIC2 CUEDC1 CYBRD1 CYP26B1 DAPK3 DAZAP2 DDX54 DECR2 DMTN DYRK3 EFEMP2 FGF12 FKBP3 GORAB H1F0 HAX1 HGS IFRD2 IKBKB KCNAB1 KCNAB2 KCNAB3 KCNB1 KIF3B KIFC3 LAPTM5 MAGEB1 MAP2 MAP3K2 MAP3K3 MAP3K5 MAPKAPK3 MARK2 MERTK MINK1 MOB3A MRPL19 NDFIP2 NHP2 NR3C1 NSRP1 NTRK1 NUDT16L1 PBX1 PRKX PRR16 PRRG1 PSMD4 RANBP10 RASL10B RASL11B RNF11 RNF7 ROBO3 RPL30 RPS6KB2 SCAMP3 SCD SCN5A SCNN1A SCNN1B SCNN1G SENP2 SERPINF1 SGK1 SGK2 SIVA1 SLC7A7 SMAD2 SMAD3 SMAD7 SNCA SPAG8 SRMS STAC STK40 TAF1B TARBP2 TBC1D7 TCEAL2 TGFB1I1 TMA16 TMEM55A TRIM41 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2J2 UBE2K UBE2L3 UBE2N VDAC2 WIBG WNK1 WNK4 YWHAG YWHAZ YY1 ZADH2 ZAK ZC3HAV1L ZDHHC3
Entrez ID 3551 23327
HPRD ID 04462 05903
Ensembl ID ENSG00000104365 ENSG00000049759
Uniprot IDs O14920 B7Z2P9 B7Z6K0 F5H602 Q96PU5
PDB IDs 3BRT 3BRV 4E3C 4KIK 2LAJ 2LB2 2LTY 2NSQ 2ONI 3JVZ 3JW0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abi  analyse  ctla4  episodes  genotyped  il4ra  il8  map3k1  mbl2  nfkbia  nfkbib  polymorphisms  prism  recurrent  rhinovirus  rs1800450ct  rs1801275gg  rs2146323aa  rs2233419ag  rs3087243ag  rs3136641tt  rs3747811at  rs3775291tc  rs4073at  rs702689aa  rs833058ct  tlr3  vegfa  wheezing 
2cl  antihypertensive  cotransporter  defective  demonstrating  emerging  enac  exchanger  highlight  hypertension  interactor  interesting  liddle  ligase  makes  na  ncc  nephron  nhe3  nkcc2  originally  progress  salt  sensitive  thiazide  transporters  ubiquitin  ubiquitylates 
Tagcloud (Difference) ?
abi  analyse  ctla4  episodes  genotyped  il4ra  il8  map3k1  mbl2  nfkbia  nfkbib  polymorphisms  prism  recurrent  rhinovirus  rs1800450ct  rs1801275gg  rs2146323aa  rs2233419ag  rs3087243ag  rs3136641tt  rs3747811at  rs3775291tc  rs4073at  rs702689aa  rs833058ct  tlr3  vegfa  wheezing 
2cl  antihypertensive  cotransporter  defective  demonstrating  emerging  enac  exchanger  highlight  hypertension  interactor  interesting  liddle  ligase  makes  na  ncc  nephron  nhe3  nkcc2  originally  progress  salt  sensitive  thiazide  transporters  ubiquitin  ubiquitylates 
Tagcloud (Intersection) ?