SNTA1 and KCNJ10

Number of citations of the paper that reports this interaction (PubMedID 15123239)
0

Data Source:
BioGRID (unspecified method)

		SNTA1	KCNJ10
Description		syntrophin alpha 1	potassium inwardly rectifying channel subfamily J member 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Anchoring Junction	Plasma Membrane Membrane Basolateral Plasma Membrane Monoatomic Ion Channel Complex Cell Body Astrocyte Projection Ciliary Base Presynapse
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Transmembrane Transporter Binding Nitric-oxide Synthase Binding ATPase Binding	Nucleotide Binding Inward Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport	Monoatomic Ion Transport Potassium Ion Transport Visual Perception Adult Walking Behavior Oligodendrocyte Development Central Nervous System Myelination Metal Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Cellular Response To Potassium Ion Regulation Of Membrane Potential Regulation Of Long-term Neuronal Synaptic Plasticity Establishment Of Localization In Cell Glutamate Reuptake Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Potassium Ion Transmembrane Transport Non-motile Cilium Assembly Potassium Ion Import Across Plasma Membrane
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Ritodrine Yohimbine Butamben
Diseases		Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)	Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance (SESAME) ; SeSAME/EAST syndrome
GWAS		HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)
Interacting Genes		76 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB ENTREP3 F8A1 FABP1 GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TIAM1 TLX3 TRA TRBV12-3 UTRN VANGL2 XRCC6	9 interacting genes: APP DLG1 DLG4 IL16 KCNJ16 PATJ SIAH1 SNCA SNTA1
Entrez ID		6640	3766
HPRD ID		03009	03732
Ensembl ID		ENSG00000101400	ENSG00000177807
Uniprot IDs		B3KTR0 Q13424	P78508
PDB IDs
Enriched GO Terms of Interacting Partners?		Plasma Membrane System Process Regulation Of System Process Membrane G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity Regulation Of Blood Circulation Circulatory System Process Vascular Process In Circulatory System Monoatomic Ion Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Heart Contraction Blood Vessel Diameter Maintenance Regulation Of Tube Size Basolateral Plasma Membrane Monoatomic Ion Transmembrane Transport Regulation Of Biological Quality Transmembrane Transport Muscle Contraction Inorganic Ion Transmembrane Transport Metal Ion Transport Monoatomic Ion Transport Regulation Of Heart Rate Inorganic Cation Transmembrane Transport Regulation Of Membrane Potential Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Cardiac Muscle Cell Action Potential Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Muscle System Process Synapse Inward Rectifier Potassium Channel Activity Synaptic Signaling Vasodilation Intracellular Signaling Cassette Regulation Of Monoatomic Ion Transmembrane Transport Adrenergic Receptor Activity CGMP-mediated Signaling Calcium-mediated Signaling Action Potential Potassium Ion Transport Regulation Of Blood Pressure Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Voltage-gated Sodium Channel Complex Signal Transduction Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Multicellular Organismal Process	Regulation Of Monoatomic Ion Transport Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Monoatomic Ion Transmembrane Transport Amyloid Fibril Formation Regulation Of Metal Ion Transport Regulation Of Membrane Potential Regulation Of Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Neuronal Synaptic Plasticity NMDA Selective Glutamate Receptor Signaling Pathway Synaptic Membrane Regulation Of Monoatomic Cation Transmembrane Transport Neuromuscular Junction Chemical Synaptic Transmission Trans-synaptic Signaling Acetylcholine Receptor Binding Synaptic Signaling Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Synaptic Transmission Regulation Of Neurotransmitter Uptake Cell Junction Organization Cellular Response To Copper Ion Establishment Or Maintenance Of Cell Polarity Regulation Of Presynapse Organization Positive Regulation Of Inflammatory Response Regulation Of Presynapse Assembly Cellular Response To Metal Ion Supramolecular Fiber Organization Ionotropic Glutamate Receptor Signaling Pathway Microglial Cell Activation Ionotropic Glutamate Receptor Binding Locomotory Behavior Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of System Process Leukocyte Activation Involved In Inflammatory Response Protein Localization To Postsynaptic Membrane Cell Junction Protein Localization To Postsynapse Regulation Of Synaptic Plasticity Response To Copper Ion Plasma Membrane Cell-cell Signaling Regulation Of Sodium Ion Transmembrane Transport Regulation Of Calcium Ion Transport Presynapse Postsynapse Ligand-gated Ion Channel Signaling Pathway Signaling Regulation Of Cell Activation
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