KCNJ10

Description		potassium inwardly rectifying channel subfamily J member 10
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Monoatomic Ion Channel Complex Cell Body Astrocyte Projection Ciliary Base Presynapse
	Molecular Function	Nucleotide Binding Inward Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Visual Perception Adult Walking Behavior Oligodendrocyte Development Central Nervous System Myelination Metal Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Cellular Response To Potassium Ion Regulation Of Membrane Potential Regulation Of Long-term Neuronal Synaptic Plasticity Establishment Of Localization In Cell Glutamate Reuptake Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Potassium Ion Transmembrane Transport Non-motile Cilium Assembly Potassium Ion Import Across Plasma Membrane
Pathways		Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs		Ritodrine Yohimbine Butamben
Diseases		Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance (SESAME) ; SeSAME/EAST syndrome
GWAS
Interacting Genes		9 interacting genes: APP DLG1 DLG4 IL16 KCNJ16 PATJ SIAH1 SNCA SNTA1
Entrez ID		3766
HPRD ID		03732
Ensembl ID		ENSG00000177807
Uniprot IDs		P78508
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Monoatomic Ion Transport Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Monoatomic Ion Transmembrane Transport Amyloid Fibril Formation Regulation Of Metal Ion Transport Regulation Of Membrane Potential Regulation Of Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Neuronal Synaptic Plasticity NMDA Selective Glutamate Receptor Signaling Pathway Synaptic Membrane Regulation Of Monoatomic Cation Transmembrane Transport Neuromuscular Junction Chemical Synaptic Transmission Trans-synaptic Signaling Acetylcholine Receptor Binding Synaptic Signaling Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Synaptic Transmission Regulation Of Neurotransmitter Uptake Cell Junction Organization Cellular Response To Copper Ion Establishment Or Maintenance Of Cell Polarity Regulation Of Presynapse Organization Positive Regulation Of Inflammatory Response Regulation Of Presynapse Assembly Cellular Response To Metal Ion Supramolecular Fiber Organization Ionotropic Glutamate Receptor Signaling Pathway Microglial Cell Activation Ionotropic Glutamate Receptor Binding Locomotory Behavior Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of System Process Leukocyte Activation Involved In Inflammatory Response Protein Localization To Postsynaptic Membrane Cell Junction Protein Localization To Postsynapse Regulation Of Synaptic Plasticity Response To Copper Ion Plasma Membrane Cell-cell Signaling Regulation Of Sodium Ion Transmembrane Transport Regulation Of Calcium Ion Transport Presynapse Postsynapse Ligand-gated Ion Channel Signaling Pathway Signaling Regulation Of Cell Activation
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