SNTA1 and MAS1

Number of citations of the paper that reports this interaction (PubMedID 15123239)
0

Data Source:
BioGRID (unspecified method)

		SNTA1	MAS1
Description		syntrophin alpha 1	MAS1 proto-oncogene, G protein-coupled receptor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Anchoring Junction	Plasma Membrane Membrane
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Transmembrane Transporter Binding Nitric-oxide Synthase Binding ATPase Binding	Angiotensin Receptor Activity G Protein-coupled Receptor Activity Angiotensin Type II Receptor Activity Protein Binding G Protein-coupled Peptide Receptor Activity Peptide Binding
	Biological Process	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport	Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Inflammatory Response Phospholipase C-activating Angiotensin-activated Signaling Pathway
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Peptide ligand-binding receptors
Drugs
Diseases		Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS		HDL cholesterol x physical activity interaction (1df test) ( 30670697) HDL cholesterol x physical activity interaction (2df test) ( 30670697)	Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Lipoprotein (a) levels ( 26377243) Metabolite levels ( 23823483)
Interacting Genes		76 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB ENTREP3 F8A1 FABP1 GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TIAM1 TLX3 TRA TRBV12-3 UTRN VANGL2 XRCC6	4 interacting genes: ACE2 AGT ARRB2 SNTA1
Entrez ID		6640	4142
HPRD ID		03009	01306
Ensembl ID		ENSG00000101400	ENSG00000130368
Uniprot IDs		B3KTR0 Q13424	P04201 W8W3P4
PDB IDs
Enriched GO Terms of Interacting Partners?		Plasma Membrane System Process Regulation Of System Process Membrane G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity Regulation Of Blood Circulation Circulatory System Process Vascular Process In Circulatory System Monoatomic Ion Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Heart Contraction Blood Vessel Diameter Maintenance Regulation Of Tube Size Basolateral Plasma Membrane Monoatomic Ion Transmembrane Transport Regulation Of Biological Quality Transmembrane Transport Muscle Contraction Inorganic Ion Transmembrane Transport Metal Ion Transport Monoatomic Ion Transport Regulation Of Heart Rate Inorganic Cation Transmembrane Transport Regulation Of Membrane Potential Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Cardiac Muscle Cell Action Potential Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Muscle System Process Synapse Inward Rectifier Potassium Channel Activity Synaptic Signaling Vasodilation Intracellular Signaling Cassette Regulation Of Monoatomic Ion Transmembrane Transport Adrenergic Receptor Activity CGMP-mediated Signaling Calcium-mediated Signaling Action Potential Potassium Ion Transport Regulation Of Blood Pressure Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Voltage-gated Sodium Channel Complex Signal Transduction Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Multicellular Organismal Process	Regulation Of System Process Regulation Of Gap Junction Assembly Positive Regulation Of Gap Junction Assembly Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Regulation Of Heart Contraction Regulation Of Cardiac Conduction Regulation Of Blood Circulation Regulation Of Muscle System Process Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal Sodium Channel Regulator Activity Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Systemic Arterial Blood Pressure System Process Regulation Of Membrane Potential Regulation Of Transport Regulation Of Vasoconstriction Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Sodium Ion Transport Regulation Of Cardiac Muscle Hypertrophy Endocytic Vesicle Membrane Regulation Of MAPK Cascade Positive Regulation Of Cell Junction Assembly Blood Vessel Diameter Maintenance Regulation Of Defense Response Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Tube Size Positive Regulation Of Membrane Hyperpolarization Regulation Of Cytokine Production G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Type 2 Angiotensin Receptor Binding Angiotensin Receptor Binding Positive Regulation Of L-proline Import Across Plasma Membrane Angiotensin-mediated Drinking Behavior Peptidyl-dipeptidase Activity Regulation Of Biological Quality Negative Regulation Of MAPK Cascade Regulation Of Blood Pressure Receptor-mediated Endocytosis Positive Regulation Of Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Regulation Of Renal Output By Angiotensin Positive Regulation Of Synaptic Transmission, Dopaminergic Entry Receptor-mediated Virion Attachment To Host Cell Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Multicellular Organismal Process
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