KCNJ10 and KCNJ16

Number of citations of the paper that reports this interaction (PMID 12923169)
13

Data Source:
HPRD (in vitro)

		KCNJ10	KCNJ16
Gene Name		potassium channel, inwardly rectifying subfamily J, member 10	potassium channel, inwardly rectifying subfamily J, member 16
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Microvillus Basolateral Plasma Membrane Apical Plasma Membrane Astrocyte Projection	Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex
	Molecular Function	Receptor Binding Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity Identical Protein Binding	Inward Rectifier Potassium Channel Activity
	Biological Process	Potassium Ion Transport Inflammatory Response Synaptic Transmission Visual Perception Adult Walking Behavior Response To Blue Light Potassium Ion Import Optic Nerve Development Central Nervous System Myelination Regulation Of Ion Transmembrane Transport Regulation Of Long-term Neuronal Synaptic Plasticity Protein Homotetramerization Response To Glucocorticoid Response To Mineralocorticoid Regulation Of Sensory Perception Of Pain L-glutamate Uptake Involved In Synaptic Transmission Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Membrane Hyperpolarization	Potassium Ion Transport Synaptic Transmission Potassium Ion Import Regulation Of Ion Transmembrane Transport
Pathways		GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Potassium transport channels Activation of G protein gated Potassium channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses	GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Potassium transport channels Activation of G protein gated Potassium channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses
Drugs
Diseases
GWAS			Palmitoleic acid (16:1n-7) plasma levels ( 23362303) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Thyrotoxic hypokalemic periodic paralysis ( 22863731)
Protein-Protein Interactions		8 interactors: APP DLG1 DLG4 IL16 INADL KCNJ16 SIAH1 SNTA1	3 interactors: KCNJ10 KCNJ15 KCNJ2
Entrez ID		3766	3773
HPRD ID		03732	16146
Ensembl ID		ENSG00000177807	ENSG00000153822
Uniprot IDs		P78508	A8K434 K7EJR9 Q9NPI9
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemotaxis Receptor Localization To Synapse Axon Guidance Regulation Of Ion Transmembrane Transport Protein Localization To Synapse Axonogenesis Synapse Organization Locomotion Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Ion Transport Cortical Actin Cytoskeleton Organization Neuron Projection Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Tight Junction Assembly Response To External Stimulus Receptor Clustering Neuromuscular Junction Development Neuron Apoptotic Process Nucleotide Phosphorylation Neuron Development Neuron Death Regulation Of Sodium Ion Transport Cell Morphogenesis Apical Junction Assembly Neuromuscular Process Controlling Balance Synapse Assembly Neuron Differentiation Cell Projection Organization Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Receptor Activity Synaptic Growth At Neuromuscular Junction Cell-cell Junction Assembly Cell Recognition Synaptic Transmission Neuromuscular Process Learning Dendrite Development Collateral Sprouting In Absence Of Injury Generation Of Neurons Neurogenesis Collateral Sprouting	Potassium Ion Import Regulation Of Resting Membrane Potential Potassium Ion Transmembrane Transport Potassium Ion Transport Potassium Ion Homeostasis Regulation Of Ion Transmembrane Transport Synaptic Transmission Regulation Of Ion Transport Monovalent Inorganic Cation Transport Protein Homotetramerization Metal Ion Transport Protein Tetramerization Cell-cell Signaling Cation Transmembrane Transport Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Cation Transport Ion Transmembrane Transport Relaxation Of Skeletal Muscle L-glutamate Uptake Involved In Synaptic Transmission Protein Homooligomerization Response To Blue Light Regulation Of Membrane Potential Transmembrane Transport Ion Transport Protein Oligomerization Cellular Potassium Ion Homeostasis L-glutamate Import Regulation Of Skeletal Muscle Contraction Metal Ion Homeostasis Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Membrane Depolarization During Cardiac Muscle Cell Action Potential Neurotransmitter Uptake Membrane Repolarization Relaxation Of Cardiac Muscle Ion Homeostasis Optic Nerve Development Amino Acid Import Positive Regulation Of Potassium Ion Transmembrane Transport Central Nervous System Myelination Relaxation Of Muscle Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Magnesium Ion Transport Regulation Of Sensory Perception Of Pain L-glutamate Transport Cardiac Muscle Cell Action Potential Involved In Contraction Positive Regulation Of Potassium Ion Transport Chemical Homeostasis Regulation Of Long-term Neuronal Synaptic Plasticity
Tagcloud ?		abcc8 acacb cacna1a camk2d cdkal1 chi csmd1 disequilibrium exome glud1 gnas hnf1a hyperinsulinism kcnh6 nos2 notch2 pde4c pik3r3 probands ryr3 scn8a slc24a6 slc37a3 sulf1 tdt tll1 trpc5 trpv3
Tagcloud (Difference) ?		abcc8 acacb cacna1a camk2d cdkal1 chi csmd1 disequilibrium exome glud1 gnas hnf1a hyperinsulinism kcnh6 nos2 notch2 pde4c pik3r3 probands ryr3 scn8a slc24a6 slc37a3 sulf1 tdt tll1 trpc5 trpv3
Tagcloud (Intersection) ?