SNTA1 and DTNA

Number of citations of the paper that reports this interaction (PMID 18468998)
17

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		SNTA1	DTNA
Gene Name		syntrophin, alpha 1	dystrobrevin, alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Cytoskeleton Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Sarcolemma Protein Complex Postsynaptic Membrane	Cytoplasm Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Sarcolemma Protein Complex Synapse
	Molecular Function	Actin Binding Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport	Striated Muscle Contraction Signal Transduction Synaptic Transmission Neuromuscular Synaptic Transmission
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		72 interactors: ABCA1 ABCC4 ACTA2 ADAMTS6 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B BAI1 BAI2 BAI3 C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6	14 interactors: ACTA1 DMD DRP2 DTNBP1 GFI1B KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 SYNC SYNM UTRN
Entrez ID		6640	1837
HPRD ID		03009	03141
Ensembl ID		ENSG00000101400	ENSG00000134769
Uniprot IDs		B4DX40 Q13424	A8K541 B7Z3X3 M0QYX6 Q9Y4J8
PDB IDs			2E5R
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Ion Transport Muscle System Process Muscle Contraction Regulation Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Metal Ion Transport Ion Transport Regulation Of Muscle Contraction Blood Circulation Negative Regulation Of Adrenergic Receptor Signaling Pathway Monovalent Inorganic Cation Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cation Transport Regulation Of Striated Muscle Contraction Cell Surface Receptor Signaling Pathway Cation Transmembrane Transport Transmembrane Transport Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Homeostasis Positive Regulation Of Cell Proliferation Ion Transmembrane Transport Potassium Ion Import Regulation Of Phosphorus Metabolic Process Behavior Response To Stimulus Regulation Of Membrane Potential Positive Regulation Of Transport Regulation Of Cellular Process Regulation Of Sodium Ion Transport CGMP Metabolic Process Positive Regulation Of Ion Transport Response To Drug Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Action Potential Regulation Of Body Fluid Levels Multicellular Organismal Response To Stress Response To Stress Cellular Response To Stimulus	Muscle Contraction Muscle System Process Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Regulation Of Ion Transport Regulation Of Ion Transmembrane Transport Regulation Of Heart Contraction Regulation Of Sodium Ion Transmembrane Transporter Activity Myotube Cell Development Actin-myosin Filament Sliding Muscle Filament Sliding Cardiac Muscle Cell Action Potential Intermediate Filament-based Process Actin-mediated Cell Contraction Muscle Fiber Development Positive Regulation Of Cell-matrix Adhesion Muscle Organ Development Myotube Differentiation Actin Filament-based Movement Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Action Potential Regulation Of Striated Muscle Contraction Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Muscle Structure Development Skeletal Muscle Tissue Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development System Development Regulation Of Muscle Contraction Striated Muscle Cell Development Synaptic Transmission Regulation Of Dopamine Receptor Signaling Pathway Skeletal Muscle Thin Filament Assembly Olfactory Nerve Development Muscle Cell Development Regulation Of Skeletal Muscle Contraction Actin Filament-based Process Skeletal Myofibril Assembly Neurotransmitter Receptor Metabolic Process Regulation Of Cell-substrate Adhesion Platelet Dense Granule Organization
Tagcloud ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound
Tagcloud (Difference) ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound
Tagcloud (Intersection) ?