SNTA1 and ATP2B2

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		SNTA1	ATP2B2
Gene Name		syntrophin, alpha 1	ATPase, Ca++ transporting, plasma membrane 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Cytoskeleton Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Sarcolemma Protein Complex Postsynaptic Membrane	Cytoplasm Endoplasmic Reticulum Plasma Membrane Cilium Integral Component Of Membrane Apical Plasma Membrane Cell Junction Neuronal Cell Body Synapse Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding	Calcium-transporting ATPase Activity Calcium Ion Binding Protein Binding Calmodulin Binding ATP Binding Protein C-terminus Binding PDZ Domain Binding Calcium-dependent ATPase Activity Metal Ion Binding
	Biological Process	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport	Transport Calcium Ion Transport Organelle Organization Lactation Blood Coagulation Sensory Perception Of Sound Locomotory Behavior Regulation Of Cell Size Cerebellar Purkinje Cell Differentiation Cerebellar Granule Cell Differentiation Neuron Differentiation Ion Transmembrane Transport Locomotion Serotonin Metabolic Process Otolith Mineralization CGMP Metabolic Process Regulation Of Synaptic Plasticity Synapse Organization Neuromuscular Process Controlling Balance Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Cytosolic Calcium Ion Homeostasis Positive Regulation Of Calcium Ion Transport Transmembrane Transport Auditory Receptor Cell Stereocilium Organization Calcium Ion Transmembrane Transport Cochlea Development
Pathways			Ion transport by P-type ATPases Ion channel transport Platelet homeostasis Reduction of cytosolic Ca++ levels Platelet calcium homeostasis
Drugs
Diseases
GWAS			Metabolite levels ( 19043545)
Protein-Protein Interactions		72 interactors: ABCA1 ABCC4 ACTA2 ADAMTS6 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B BAI1 BAI2 BAI3 C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6	8 interactors: DLG1 DLG2 DLG4 ERBB2IP PDZD11 PRKCA SLC9A3R2 SNTA1
Entrez ID		6640	491
HPRD ID		03009	00160
Ensembl ID		ENSG00000101400	ENSG00000157087
Uniprot IDs		B4DX40 Q13424	Q01814 Q4J699 Q4LE63
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Ion Transport Muscle System Process Muscle Contraction Regulation Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Metal Ion Transport Ion Transport Regulation Of Muscle Contraction Blood Circulation Negative Regulation Of Adrenergic Receptor Signaling Pathway Monovalent Inorganic Cation Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cation Transport Regulation Of Striated Muscle Contraction Cell Surface Receptor Signaling Pathway Cation Transmembrane Transport Transmembrane Transport Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Homeostasis Positive Regulation Of Cell Proliferation Ion Transmembrane Transport Potassium Ion Import Regulation Of Phosphorus Metabolic Process Behavior Response To Stimulus Regulation Of Membrane Potential Positive Regulation Of Transport Regulation Of Cellular Process Regulation Of Sodium Ion Transport CGMP Metabolic Process Positive Regulation Of Ion Transport Response To Drug Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Action Potential Regulation Of Body Fluid Levels Multicellular Organismal Response To Stress Response To Stress Cellular Response To Stimulus	Establishment Or Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Cell Polarity Receptor Clustering Nucleotide Phosphorylation Maintenance Of Apical/basal Cell Polarity Membrane Organization Protein Localization To Membrane Cell-cell Signaling Maintenance Of Cell Polarity Synaptic Transmission Cellular Protein Localization Cortical Actin Cytoskeleton Organization Asymmetric Protein Localization Cortical Cytoskeleton Organization Regulation Of Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Protein Localization Regulation Of Sodium Ion Transport Negative Regulation Of Intracellular Signal Transduction Regulation Of Ion Transmembrane Transport Endomembrane System Organization Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Vasoconstriction By Circulating Norepinephrine Small Molecule Metabolic Process Cellular Localization Basal Protein Localization Histone H3-T6 Phosphorylation Cell-cell Junction Assembly Nucleotide Metabolic Process Chemotaxis Regulation Of Ion Transport Nucleobase-containing Small Molecule Metabolic Process Protein Localization To Plasma Membrane Regulation Of Muscle Contraction Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Heart Contraction Synapse Organization Regulation Of Intracellular Signal Transduction Protein Localization To Basolateral Plasma Membrane T Cell Cytokine Production Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Behavior Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of Grooming Behavior Hard Palate Development Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering
Tagcloud ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound	ankrd2 arg autoprocessing bak calpain calpains capability cleavages controllers destabilizing eliminating favor glu glun2a grm1 ica512 igfbp2 lived mechanistically multitude nonprocessive oligomeric phe phosphatases pressures proteases rule underlies virtually
Tagcloud (Difference) ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound	ankrd2 arg autoprocessing bak calpain calpains capability cleavages controllers destabilizing eliminating favor glu glun2a grm1 ica512 igfbp2 lived mechanistically multitude nonprocessive oligomeric phe phosphatases pressures proteases rule underlies virtually
Tagcloud (Intersection) ?