SNTA1 and NAT1

Number of citations: 0 (PubMedID 15123239)
Data Source: BioGRID (unspecified method)

		SNTA1	NAT1
Name		syntrophin alpha 1	N-acetyltransferase 1
Structure		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Syntrophin Complex Membrane Lateral Plasma Membrane Neuromuscular Junction Protein-containing Complex Sarcolemma Anchoring Junction	Cytoplasm Cytosol
	Molecular Function	Actin Binding Structural Molecule Activity Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Transmembrane Transporter Binding Nitric-oxide Synthase Binding ATPase Binding	Arylamine N-acetyltransferase Activity Protein Binding Acetyltransferase Activity Transferase Activity Acyltransferase Activity
	Biological Process	Regulation Of Heart Rate Muscle Contraction Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport	Xenobiotic Metabolic Process
Pathways		Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)	Acetylation Paracetamol ADME
Diseases		Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)	None
GWAS		HDL cholesterol x physical activity interaction (1df test) ( 30670697 ) HDL cholesterol x physical activity interaction (2df test) ( 30670697 )	Femur bone mineral density x serum urate levels interaction ( 34046847 ) Metabolite levels ( 23823483 ) Night sleep phenotypes ( 27126917 ) Serum bilirubin levels x Mediterranean diet adherence interaction in metabolic syndrome ( 30621171 )
Interacting Genes		76 interacting genes: ABCA1 ABCC4 ACTA2 ADAMTS6 ADGRB1 ADGRB2 ADGRB3 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA DTNB ENTREP3 F8A1 FABP1 GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 RPS6KA1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TIAM1 TLX3 TRA TRBV12-3 UTRN VANGL2 XRCC6	2 interacting genes: NAA10 SNTA1
Entrez ID		6640	9
HPRD ID		03009	00149
Ensembl ID		ENSG00000101400	ENSG00000171428
Uniprot IDs		B3KTR0 Q13424	F5H5R8 P18440 Q400J6
PDB IDs		Not available	2IJA 2PQT
GO Terms Enriched among Interactors		Plasma Membrane System Process Regulation Of System Process Membrane G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Activity Regulation Of Blood Circulation Circulatory System Process Vascular Process In Circulatory System Monoatomic Ion Channel Complex Regulation Of Multicellular Organismal Process Regulation Of Heart Contraction Blood Vessel Diameter Maintenance Regulation Of Tube Size Basolateral Plasma Membrane Monoatomic Ion Transmembrane Transport Regulation Of Biological Quality Transmembrane Transport Muscle Contraction Inorganic Ion Transmembrane Transport Metal Ion Transport Monoatomic Ion Transport Regulation Of Heart Rate Inorganic Cation Transmembrane Transport Regulation Of Membrane Potential Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Cardiac Muscle Cell Action Potential Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Muscle System Process Synapse Inward Rectifier Potassium Channel Activity Synaptic Signaling Vasodilation Intracellular Signaling Cassette Regulation Of Monoatomic Ion Transmembrane Transport Adrenergic Receptor Activity CGMP-mediated Signaling Calcium-mediated Signaling Action Potential Potassium Ion Transport Regulation Of Blood Pressure Regulation Of Muscle Contraction Regulation Of Monoatomic Ion Transport Voltage-gated Sodium Channel Complex Signal Transduction Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Multicellular Organismal Process	Syntrophin Complex Regulation Of Centromeric Sister Chromatid Cohesion Protein-N-terminal-alanine Acetyltransferase Activity Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Negative Regulation Of Sister Chromatid Cohesion Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity NatA Complex Mammary Gland Branching Involved In Pregnancy Oviduct Epithelium Development Protein-N-terminal Amino-acid Acetyltransferase Activity Conditioned Place Preference Mammary Gland Duct Morphogenesis Internal Protein Amino Acid Acetylation Nitric-oxide Synthase Binding N-terminal Protein Amino Acid Acetylation Dystrophin-associated Glycoprotein Complex Ventricular Cardiac Muscle Cell Action Potential Regulation Of Sister Chromatid Cohesion Acetyltransferase Activity N-acetyltransferase Activity Branching Involved In Mammary Gland Duct Morphogenesis Startle Response Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Female Gonad Development Sodium Channel Regulator Activity Protein Acetylation Maternal Process Involved In Female Pregnancy Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Membrane Repolarization Mammary Gland Development Regulation Of Sodium Ion Transmembrane Transport Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Cardiac Muscle Cell Action Potential Lateral Plasma Membrane Regulation Of Sodium Ion Transport Ribosome Binding Neuromuscular Junction Negative Regulation Of Chromosome Organization PDZ Domain Binding ATPase Binding