SNTA1 and GLS

Number of citations of the paper that reports this interaction (PMID 11163757)
12

Data Source:
HPRD (in vitro, two hybrid)

		SNTA1	GLS
Gene Name		syntrophin, alpha 1	glutaminase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Cytoskeleton Syntrophin Complex Lateral Plasma Membrane Cell Junction Neuromuscular Junction Sarcolemma Protein Complex Postsynaptic Membrane	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Actin Binding Protein Binding Calmodulin Binding Sodium Channel Regulator Activity PDZ Domain Binding Ion Channel Binding Nitric-oxide Synthase Binding ATPase Binding	Glutaminase Activity Protein Binding
	Biological Process	Regulation Of Heart Rate Regulation Of Vasoconstriction By Circulating Norepinephrine Muscle Contraction Neuromuscular Junction Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport	Suckling Behavior Regulation Of Respiratory Gaseous Exchange By Neurological System Process Glutamate Biosynthetic Process Glutamine Catabolic Process Synaptic Transmission Neurotransmitter Secretion Cellular Amino Acid Biosynthetic Process Glutamate Secretion Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Protein Homotetramerization
Pathways			Neurotransmitter Release Cycle Amino acid synthesis and interconversion (transamination) Glutamate Neurotransmitter Release Cycle Metabolism of amino acids and derivatives Transmission across Chemical Synapses
Drugs			L-Glutamic Acid
Diseases
GWAS
Protein-Protein Interactions		72 interactors: ABCA1 ABCC4 ACTA2 ADAMTS6 ADH5 ADRA1D ADRA2A ADRB1 AGTR2 ATP2B2 ATP6V0B BAI1 BAI2 BAI3 C3AR1 CALM1 CD3E CNKSR2 COPB1 DGKZ DMD DTNA F8A1 FABP1 FAM189B GDA GLS GLS2 GOLGA2 GRB2 GUCY1A2 HTR2B HTR2C IL2RA IL9 ITGB5 KCNA4 KCNA5 KCNJ10 KCNJ12 KCNJ15 KCNJ4 KIF1B LMO1 MAP4 MAPK12 MAS1 MAST1 MCM7 MED8 MTMR2 NAT1 NMU NOS1 PFN2 PRLHR PSKH1 SCN1A SCN4A SCN5A SCTR SLC16A7 SLC1A7 SLC2A3 SLC6A3 SSTR1 TGFA TLX3 TRA TRBV12-3 UTRN XRCC6	4 interactors: ATXN10 PARD6A SNTA1 TAX1BP3
Entrez ID		6640	2744
HPRD ID		03009	00700
Ensembl ID		ENSG00000101400	ENSG00000115419
Uniprot IDs		B4DX40 Q13424	O94925 Q68D38
PDB IDs			3CZD 3UNW 3UO9 3VOY 3VOZ 3VP0 3VP1 3VP2 3VP3 3VP4
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Synaptic Transmission Regulation Of Ion Transmembrane Transport Signaling Cell Communication Regulation Of Ion Transport Muscle System Process Muscle Contraction Regulation Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Metal Ion Transport Ion Transport Regulation Of Muscle Contraction Blood Circulation Negative Regulation Of Adrenergic Receptor Signaling Pathway Monovalent Inorganic Cation Transport Regulation Of Sodium Ion Transmembrane Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Cation Transport Regulation Of Striated Muscle Contraction Cell Surface Receptor Signaling Pathway Cation Transmembrane Transport Transmembrane Transport Regulation Of Adrenergic Receptor Signaling Pathway Regulation Of Ion Homeostasis Positive Regulation Of Cell Proliferation Ion Transmembrane Transport Potassium Ion Import Regulation Of Phosphorus Metabolic Process Behavior Response To Stimulus Regulation Of Membrane Potential Positive Regulation Of Transport Regulation Of Cellular Process Regulation Of Sodium Ion Transport CGMP Metabolic Process Positive Regulation Of Ion Transport Response To Drug Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Action Potential Regulation Of Body Fluid Levels Multicellular Organismal Response To Stress Response To Stress Cellular Response To Stimulus	Regulation Of Vasoconstriction By Circulating Norepinephrine Negative Regulation Of Peptidyl-cysteine S-nitrosylation Negative Regulation Of Protein Localization To Cell Surface Cell-cell Junction Maintenance Activation Of Cdc42 GTPase Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Positive Regulation Of Cdc42 GTPase Activity Regulation Of Protein Localization To Cell Surface Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization Cellular Component Maintenance Regulation Of Cdc42 GTPase Activity Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Cdc42 Protein Signal Transduction Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Activation Of Rho GTPase Activity Regulation Of Cardiac Muscle Cell Contraction Tight Junction Assembly Neuromuscular Junction Development Activation Of Ras GTPase Activity Regulation Of Vasoconstriction Rho Protein Signal Transduction
Tagcloud ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound	antigenically aphis bursa bursal conformationally d78 delaware dele delmarva ecorii georgia haeiii heptapeptide hypervariable ibdv miss mississippi pbg98 peninsula serologic southeastern spei stui styi swasasgs taqi univax vac vp2
Tagcloud (Difference) ?		acquisition assays depletion displacement downregulate e3b1 effectively emphasise eps8 explored forming generation grb2 healing immunoprecipitation involving malignancy migration migratory overexpressed p66shc predominantly rac1 ros shrnas sirnas sos1 syntrophin wound	antigenically aphis bursa bursal conformationally d78 delaware dele delmarva ecorii georgia haeiii heptapeptide hypervariable ibdv miss mississippi pbg98 peninsula serologic southeastern spei stui styi swasasgs taqi univax vac vp2
Tagcloud (Intersection) ?