KCNJ10 and IL16

Number of citations of the paper that reports this interaction (PMID 10479680)
9

Data Source:
BioGRID (two hybrid, pull down)
HPRD (two hybrid, in vitro)

		KCNJ10	IL16
Gene Name		potassium channel, inwardly rectifying subfamily J, member 10	interleukin 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Microvillus Basolateral Plasma Membrane Apical Plasma Membrane Astrocyte Projection	Extracellular Space Nucleus Cytoplasm Plasma Membrane
	Molecular Function	Receptor Binding Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity Identical Protein Binding	Cytokine Activity
	Biological Process	Potassium Ion Transport Inflammatory Response Synaptic Transmission Visual Perception Adult Walking Behavior Response To Blue Light Potassium Ion Import Optic Nerve Development Central Nervous System Myelination Regulation Of Ion Transmembrane Transport Regulation Of Long-term Neuronal Synaptic Plasticity Protein Homotetramerization Response To Glucocorticoid Response To Mineralocorticoid Regulation Of Sensory Perception Of Pain L-glutamate Uptake Involved In Synaptic Transmission Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Membrane Hyperpolarization	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Immune Response Viral Process Leukocyte Chemotaxis Induction Of Positive Chemotaxis
Pathways		GABA B receptor activation Inwardly rectifying K+ channels GABA receptor activation Potassium transport channels Activation of G protein gated Potassium channels Activation of GABAB receptors Potassium Channels Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell G protein gated Potassium channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Transmission across Chemical Synapses
Drugs
Diseases
GWAS			Inattentive symptoms ( 18821565)
Protein-Protein Interactions		8 interactors: APP DLG1 DLG4 IL16 INADL KCNJ16 SIAH1 SNTA1	28 interactors: CASP3 CD4 CDK1 CSNK2A1 CSNK2A2 DMRTB1 EFEMP2 GABPB1 GRIN2A GRIN2B GRIN2C GRIN2D HDAC3 KCNA3 KCND1 KCND2 KCNJ1 KCNJ10 KCNJ15 KCNJ2 KCNJ4 KDM1A PPP1R12A PPP1R12B PPP1R12C SSSCA1 SUV39H1 USHBP1
Entrez ID		3766	3603
HPRD ID		03732	04329
Ensembl ID		ENSG00000177807	ENSG00000172349
Uniprot IDs		P78508	Q14005 Q9UME6
PDB IDs			1I16 1X6D
Enriched GO Terms of Interacting Partners?		Chemotaxis Receptor Localization To Synapse Axon Guidance Regulation Of Ion Transmembrane Transport Protein Localization To Synapse Axonogenesis Synapse Organization Locomotion Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Ion Transport Cortical Actin Cytoskeleton Organization Neuron Projection Morphogenesis Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Tight Junction Assembly Response To External Stimulus Receptor Clustering Neuromuscular Junction Development Neuron Apoptotic Process Nucleotide Phosphorylation Neuron Development Neuron Death Regulation Of Sodium Ion Transport Cell Morphogenesis Apical Junction Assembly Neuromuscular Process Controlling Balance Synapse Assembly Neuron Differentiation Cell Projection Organization Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Receptor Activity Synaptic Growth At Neuromuscular Junction Cell-cell Junction Assembly Cell Recognition Synaptic Transmission Neuromuscular Process Learning Dendrite Development Collateral Sprouting In Absence Of Injury Generation Of Neurons Neurogenesis Collateral Sprouting	Synaptic Transmission Potassium Ion Transmembrane Transport Potassium Ion Transport Potassium Ion Import Cell-cell Signaling Cation Transmembrane Transport Signaling Cell Communication Ion Transmembrane Transport Metal Ion Transport Regulation Of Ion Transmembrane Transport Cation Transport Transmembrane Transport Ion Transport Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Ion Transport Monovalent Inorganic Cation Transport Regulation Of Membrane Potential Regulation Of Cellular Process Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Sensory Perception Of Pain Startle Response Directional Locomotion Protein Homooligomerization Membrane Depolarization Negative Regulation Of Protein Catabolic Process Neuromuscular Process Regulation Of Resting Membrane Potential Regulation Of Neurological System Process Regulation Of Protein Catabolic Process Cell Cycle Regulation Of Excitatory Postsynaptic Membrane Potential Mitotic Cell Cycle Process Regulation Of Postsynaptic Membrane Potential Response To Wounding Protein Complex Assembly Cell Cycle Process Protein Oligomerization Negative Regulation Of Cell Cycle Potassium Ion Homeostasis Mitotic Cell Cycle Negative Regulation Of Chromosome Organization Locomotion G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Cellular Process Response To External Stimulus
Tagcloud ?		abcc8 acacb cacna1a camk2d cdkal1 chi csmd1 disequilibrium exome glud1 gnas hnf1a hyperinsulinism kcnh6 nos2 notch2 pde4c pik3r3 probands ryr3 scn8a slc24a6 slc37a3 sulf1 tdt tll1 trpc5 trpv3
Tagcloud (Difference) ?		abcc8 acacb cacna1a camk2d cdkal1 chi csmd1 disequilibrium exome glud1 gnas hnf1a hyperinsulinism kcnh6 nos2 notch2 pde4c pik3r3 probands ryr3 scn8a slc24a6 slc37a3 sulf1 tdt tll1 trpc5 trpv3
Tagcloud (Intersection) ?