BMP4 and BMPR2

  • Number of citations of the paper that reports this interaction (PMID 7644468)
  • 60
  • Data Source:
  • HPRD (in vitro, in vivo)

BMP4

BMPR2

Gene Name bone morphogenetic protein 4 bone morphogenetic protein receptor, type II (serine/threonine kinase)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Colorectal cancer ( 19011631)
  • Dental caries ( 23259602)
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
  • Parkinson's disease ( 19915575)
  • Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions 15 interactors: BGN BMP8B BMPER BMPR1A BMPR1B BMPR2 CHRDL1 CHRDL2 GREM2 HTRA1 NOG SOSTDC1 STAP2 TWSG1 ZFYVE9 49 interactors: ACTR8 ACVR1 ACVR1B ARSA BMP10 BMP2 BMP4 BMP6 BMP7 BMPR1A BMPR1B C4BPA CCDC89 CES1 CRYAB CTBP1 DYNLT1 FHL2 FOXL1 FRS3 GDF2 GDF5 GDF6 GDF9 HNRNPR LIMK1 LMX1A LSM10 LSP1 MAP3K8 MAPK8 MERTK MOS NBEA NOP56 PDZRN3 PMPCA PPP1CC PRKCB RABGGTA SULT1E1 TGFBR1 TOPBP1 TRIB3 TRPC1 TSR1 TUBB TUBB4A TWF1
Entrez ID 652 659
HPRD ID 00207 02880
Ensembl ID ENSG00000125378 ENSG00000204217
Uniprot IDs P12644 Q53XC5 Q13873
PDB IDs 2HLQ 3G2F
Enriched GO Terms of Interacting Partners?
Tagcloud ?
agonists  antagonists  apoptosis  bmp2  causes  complete  controlling  directly  embryonal  example  exert  identification  induce  malignant  members  p19  prevents  ra  regulate  requires  retinoic  retinoid  retinoids  specifically  sufficient  synergize  transforming  variety 
apoptotic  autophagy  bmprs  bmps  chondrosarcoma  chondrosarcomas  clinicopathological  crucial  dedifferentiated  eventually  find  g2  inconsistent  interfering  mdm2  morphogenetic  multifunctional  predict  prevalent  promoted  protective  repression  sensitized  silencing  somewhat  tumorigenesis  tumorigenicity  xiap 
Tagcloud (Difference) ?
agonists  antagonists  apoptosis  bmp2  causes  complete  controlling  directly  embryonal  example  exert  identification  induce  malignant  members  p19  prevents  ra  regulate  requires  retinoic  retinoid  retinoids  specifically  sufficient  synergize  transforming  variety 
apoptotic  autophagy  bmprs  bmps  chondrosarcoma  chondrosarcomas  clinicopathological  crucial  dedifferentiated  eventually  find  g2  inconsistent  interfering  mdm2  morphogenetic  multifunctional  predict  prevalent  promoted  protective  repression  sensitized  silencing  somewhat  tumorigenesis  tumorigenicity  xiap 
Tagcloud (Intersection) ?