BMPR2 and NOP56

Number of citations of the paper that reports this interaction (PMID 15188402)
20

Data Source:
HPRD (in vitro)

		BMPR2	NOP56
Gene Name		bone morphogenetic protein receptor, type II (serine/threonine kinase)	NOP56 ribonucleoprotein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Caveola Basal Plasma Membrane Cell Surface Apical Plasma Membrane Dendrite Neuronal Cell Body Spanning Component Of Plasma Membrane	Nucleoplasm Nucleolus Small Nucleolar Ribonucleoprotein Complex Cytoplasm Membrane Box C/D SnoRNP Complex Pre-snoRNP Complex
	Molecular Function	Receptor Signaling Protein Serine/threonine Kinase Activity Transforming Growth Factor Beta-activated Receptor Activity Protein Binding ATP Binding Activin Receptor Activity, Type II Growth Factor Binding Metal Ion Binding	RNA Binding Protein Binding SnoRNA Binding Poly(A) RNA Binding
	Biological Process	Mesoderm Formation Positive Regulation Of Endothelial Cell Proliferation Lymphangiogenesis Blood Vessel Remodeling Chondrocyte Development Negative Regulation Of Systemic Arterial Blood Pressure Transcription From RNA Polymerase II Promoter Protein Phosphorylation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Brain Development Cellular Response To Starvation Anterior/posterior Pattern Specification Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Lung Blood Pressure Signal Transduction By Phosphorylation Proteoglycan Biosynthetic Process Negative Regulation Of Cell Growth Positive Regulation Of Bone Mineralization BMP Signaling Pathway Positive Regulation Of BMP Signaling Pathway Activin Receptor Signaling Pathway Regulation Of Cell Proliferation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Vasoconstriction Vascular Endothelial Growth Factor Receptor Signaling Pathway Lung Alveolus Development Positive Regulation Of Axon Extension Involved In Axon Guidance Limb Development Endochondral Bone Morphogenesis Lymphatic Endothelial Cell Differentiation Artery Development Venous Blood Vessel Development Positive Regulation Of Cartilage Development Retina Vasculature Development In Camera-type Eye Negative Regulation Of Chondrocyte Proliferation Negative Regulation Of DNA Biosynthetic Process	RRNA Modification RRNA Processing
Pathways		Signaling by BMP	Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Urate levels ( 23263486)
Protein-Protein Interactions		49 interactors: ACTR8 ACVR1 ACVR1B ARSA BMP10 BMP2 BMP4 BMP6 BMP7 BMPR1A BMPR1B C4BPA CCDC89 CES1 CRYAB CTBP1 DYNLT1 FHL2 FOXL1 FRS3 GDF2 GDF5 GDF6 GDF9 HNRNPR LIMK1 LMX1A LSM10 LSP1 MAP3K8 MAPK8 MERTK MOS NBEA NOP56 PDZRN3 PMPCA PPP1CC PRKCB RABGGTA SULT1E1 TGFBR1 TOPBP1 TRIB3 TRPC1 TSR1 TUBB TUBB4A TWF1	5 interactors: BMPR2 CSNK2A1 FBL KLF6 TCOF1
Entrez ID		659	10528
HPRD ID		02880	10119
Ensembl ID		ENSG00000204217	ENSG00000101361
Uniprot IDs		Q13873	O00567
PDB IDs		2HLQ 3G2F
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation BMP Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway SMAD Protein Signal Transduction Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Regulation Of Protein Phosphorylation Activin Receptor Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Ossification Protein Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Cell Development Regulation Of Bone Mineralization Regulation Of MAPK Cascade Regulation Of Osteoblast Differentiation Regulation Of Phosphorylation Regulation Of Cell Differentiation Phosphorylation Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Phosphorus Metabolic Process Growth Signal Transduction By Phosphorylation Regulation Of Signal Transduction Cartilage Development Regulation Of Ossification Positive Regulation Of Cell Differentiation Regulation Of Cellular Component Organization Regulation Of Signaling Regulation Of Cartilage Development Regulation Of Growth Cell Surface Receptor Signaling Pathway Connective Tissue Development Positive Regulation Of Cartilage Development Phosphate-containing Compound Metabolic Process Peptidyl-threonine Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Protein Modification Process Response To Stimulus	RNA Metabolic Process Histone Glutamine Methylation Positive Regulation Of Cell Growth Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Lung Blood Pressure Peptidyl-glutamine Methylation Negative Regulation Of Chondrocyte Proliferation Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Negative Regulation Of Vasoconstriction Developmental Process Nitrogen Compound Metabolic Process SnoRNA Metabolic Process Positive Regulation Of Growth Positive Regulation Of Axon Extension Involved In Axon Guidance Lymphatic Endothelial Cell Differentiation Cell Differentiation Gene Expression Regulation Of Cell Growth Cellular Macromolecule Biosynthetic Process Lymphangiogenesis Macromolecule Biosynthetic Process Lymph Vessel Morphogenesis Regulation Of Axon Extension Involved In Axon Guidance Venous Blood Vessel Development System Development Retina Vasculature Development In Camera-type Eye Lymph Vessel Development Negative Regulation Of Systemic Arterial Blood Pressure Negative Regulation Of DNA Biosynthetic Process RRNA Transcription Skeletal System Development Regulation Of Growth Activin Receptor Signaling Pathway Multicellular Organismal Development Transcription From RNA Polymerase I Promoter Biosynthetic Process Chondrocyte Development Anatomical Structure Development Positive Regulation Of BMP Signaling Pathway Mitotic Spindle Checkpoint Positive Regulation Of Axon Extension Positive Regulation Of Bone Mineralization Negative Regulation Of Chromosome Segregation Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Cartilage Development
Tagcloud ?		apoptotic autophagy bmprs bmps chondrosarcoma chondrosarcomas clinicopathological crucial dedifferentiated eventually find g2 inconsistent interfering mdm2 morphogenetic multifunctional predict prevalent promoted protective repression sensitized silencing somewhat tumorigenesis tumorigenicity xiap	als amyotrophic asidan ataxia causative cerebellum cerebrum cords degeneration fus fused g93a granular hypoglossal liposarcoma lumbar motor neuron nicknamed nucleolar purkinje relating sarcoma sca sod1 spinocerebellar tg translocated
Tagcloud (Difference) ?		apoptotic autophagy bmprs bmps chondrosarcoma chondrosarcomas clinicopathological crucial dedifferentiated eventually find g2 inconsistent interfering mdm2 morphogenetic multifunctional predict prevalent promoted protective repression sensitized silencing somewhat tumorigenesis tumorigenicity xiap	als amyotrophic asidan ataxia causative cerebellum cerebrum cords degeneration fus fused g93a granular hypoglossal liposarcoma lumbar motor neuron nicknamed nucleolar purkinje relating sarcoma sca sod1 spinocerebellar tg translocated
Tagcloud (Intersection) ?