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BMPR2 and RABGGTA
Number of citations of the paper that reports this interaction (PubMedID
15188402
)
0
Data Source:
HPRD
(in vitro)
BMPR2
RABGGTA
Description
bone morphogenetic protein receptor type 2
Rab geranylgeranyltransferase subunit alpha
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleoplasm
Plasma Membrane
Caveola
Clathrin-coated Pit
Adherens Junction
Basal Plasma Membrane
Cell Surface
Postsynaptic Density
Membrane
Apical Plasma Membrane
Cell Junction
Axon
Dendrite
Neuronal Cell Body
Organelle
Receptor Complex
Cell Body
Cytoplasm
Cytosol
Plasma Membrane
Rab-protein Geranylgeranyltransferase Complex
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Transforming Growth Factor Beta Receptor Activity
Protein Binding
ATP Binding
Kinase Activity
Activin Receptor Activity, Type II
Transferase Activity
Growth Factor Binding
BMP Binding
Cadherin Binding
Metal Ion Binding
BMP Receptor Activity
Protein Tyrosine Kinase Binding
Prenyltransferase Activity
Protein Geranylgeranyltransferase Activity
Rab Geranylgeranyltransferase Activity
Protein Binding
Zinc Ion Binding
Protein Prenyltransferase Activity
Transferase Activity
Small GTPase Binding
Biological Process
Regulation Of Cell Growth
Blood Vessel Development
Osteoblast Differentiation
Mesoderm Formation
Maternal Placenta Development
Endothelial Cell Proliferation
Vasculature Development
Lymphangiogenesis
Blood Vessel Remodeling
Chondrocyte Development
Negative Regulation Of Systemic Arterial Blood Pressure
Outflow Tract Septum Morphogenesis
Outflow Tract Morphogenesis
Aortic Valve Development
Pulmonary Valve Development
Atrioventricular Valve Morphogenesis
Mitral Valve Morphogenesis
Tricuspid Valve Morphogenesis
Endocardial Cushion Development
Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cell Population Proliferation
Cellular Response To Starvation
Tissue Development
Anterior/posterior Pattern Specification
Positive Regulation Of Gene Expression
Positive Regulation Of Epithelial Cell Migration
Regulation Of Lung Blood Pressure
Cell Differentiation
Proteoglycan Biosynthetic Process
Negative Regulation Of Cell Growth
Lung Development
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Activin Receptor Signaling Pathway
Positive Regulation Of Locomotion
Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Ossification
Negative Regulation Of Vasoconstriction
Positive Regulation Of Transcription By RNA Polymerase II
Lung Alveolus Development
Negative Regulation Of Smooth Muscle Cell Proliferation
Cardiac Muscle Tissue Development
Positive Regulation Of Axon Extension Involved In Axon Guidance
Stem Cell Differentiation
Negative Regulation Of Muscle Cell Differentiation
Retina Development In Camera-type Eye
Limb Development
Endochondral Bone Morphogenesis
Positive Regulation Of SMAD Protein Signal Transduction
Ventricular Septum Morphogenesis
Atrial Septum Morphogenesis
Lung Vasculature Development
Lymphatic Endothelial Cell Differentiation
Artery Development
Venous Blood Vessel Development
Positive Regulation Of Cartilage Development
Retina Vasculature Development In Camera-type Eye
Pharyngeal Arch Artery Morphogenesis
Cellular Response To Growth Factor Stimulus
Cellular Response To BMP Stimulus
Endothelial Cell Apoptotic Process
Negative Regulation Of Chondrocyte Proliferation
Semi-lunar Valve Development
Regulation Of Multicellular Organismal Development
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Visual Perception
Protein Geranylgeranylation
Protein Modification Process
Pathways
Signaling by BMP
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
RAB geranylgeranylation
Drugs
Dibotermin alfa
Fostamatinib
N-Formylmethionine
Farnesyl diphosphate
Geranylgeranyl diphosphate
Diseases
GWAS
High light scatter reticulocyte percentage of red cells (
32888494
)
Intelligence (MTAG) (
29326435
)
Mean corpuscular hemoglobin (
32888494
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
PR interval (
32439900
)
Reticulocyte fraction of red cells (
32888494
)
Triglyceride levels (
32154731
32203549
)
Urate levels (
23263486
)
Interacting Genes
53 interacting genes:
ACTR8
ACVR1
ACVR1B
ARSA
BMP10
BMP2
BMP4
BMP6
BMP7
BMPR1A
BMPR1B
C4BPA
CCDC89
CES1
CRIPTO
CRYAB
CTBP1
DYNLT1
FHL2
FOXL1
FRS3
GDF2
GDF5
GDF6
GDF9
HNRNPR
INHBA
INHBB
LIMK1
LMX1A
LSM10
LSP1
MAP3K8
MAPK8
MERTK
MOS
NBEA
NOP56
PDZRN3
PMPCA
PPP1CC
PRKCB
RABGGTA
SMURF1
SULT1E1
TGFBR1
TOPBP1
TRIB3
TRPC1
TSR1
TUBB
TUBB4A
TWF1
2 interacting genes:
BMPR2
RAB1A
Entrez ID
659
5875
HPRD ID
02880
03547
Ensembl ID
ENSG00000204217
ENSG00000100949
Uniprot IDs
Q13873
Q92696
PDB IDs
2HLQ
3G2F
6UNP
7PPA
7PPB
7PPC
7U5O
Enriched GO Terms of Interacting Partners
?
Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway
Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of SMAD Protein Signal Transduction
Regulation Of SMAD Protein Signal Transduction
Positive Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
BMP Signaling Pathway
Activin Receptor Signaling Pathway
Enzyme-linked Receptor Protein Signaling Pathway
Cellular Response To BMP Stimulus
Positive Regulation Of Cartilage Development
Growth Factor Activity
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Cartilage Development
Osteoblast Differentiation
Positive Regulation Of Cell Differentiation
Positive Regulation Of Bone Mineralization
Regulation Of Multicellular Organismal Development
Heart Development
Cytokine Activity
Cellular Response To Growth Factor Stimulus
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Positive Regulation Of Biomineral Tissue Development
Positive Regulation Of Multicellular Organismal Process
Cell Surface Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Activity, Type I
Positive Regulation Of Ossification
Regulation Of Cell Differentiation
Response To Growth Factor
Positive Regulation Of Developmental Process
Cartilage Development
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Multicellular Organismal Process
Positive Regulation Of Osteoblast Differentiation
Regulation Of Developmental Process
Positive Regulation Of Signal Transduction
Regulation Of Ossification
Regulation Of Bone Mineralization
SMAD Binding
Cell Differentiation
Regulation Of Chondrocyte Differentiation
Animal Organ Development
Enzyme Activator Complex
Regulation Of Osteoblast Differentiation
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Endocardial Cushion Formation
BMP Receptor Binding
Cellular Developmental Process
Regulation Of Growth
Protein Kinase Activity
Cadherin Binding
Positive Regulation Of Axon Extension Involved In Axon Guidance
Negative Regulation Of Chondrocyte Proliferation
Regulation Of Lung Blood Pressure
Aortic Valve Development
Lymphatic Endothelial Cell Differentiation
BMP Receptor Activity
Pulmonary Valve Development
Tricuspid Valve Morphogenesis
Venous Blood Vessel Development
Negative Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Negative Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Activin Receptor Activity, Type II
Endochondral Bone Morphogenesis
Transforming Growth Factor Beta Receptor Activity
Semi-lunar Valve Development
Mitral Valve Morphogenesis
Growth Hormone Secretion
Virion Assembly
Maternal Placenta Development
Lung Vasculature Development
Pharyngeal Arch Artery Morphogenesis
Endothelial Cell Apoptotic Process
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Negative Regulation Of Vasoconstriction
Endocardial Cushion Development
Regulation Of Axon Extension Involved In Axon Guidance
Lymphangiogenesis
Retina Vasculature Development In Camera-type Eye
Atrial Septum Morphogenesis
Establishment Of Endothelial Intestinal Barrier
Heart Valve Development
BMP Binding
Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Atrioventricular Valve Morphogenesis
Cell Development
Chondrocyte Development
Negative Regulation Of Systemic Arterial Blood Pressure
Positive Regulation Of Glycoprotein Metabolic Process
Establishment Of Melanosome Localization
Melanosome Localization
COPII-coated Vesicle Cargo Loading
Melanosome Transport
Pigment Granule Transport
Pigment Granule Localization
Outflow Tract Septum Morphogenesis
Endothelial Cell Differentiation
Activin Receptor Signaling Pathway
Cellular Response To BMP Stimulus
Positive Regulation Of Cartilage Development
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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