ZFP36L1

Gene Name		ZFP36 ring finger protein-like 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity MRNA Binding Protein Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Vasculogenesis Proepicardium Development Regulation Of Transcription, DNA-templated Regulation Of Translation Apoptotic Process Heart Development Cell Proliferation Gene Expression Neural Tube Development T Cell Differentiation In Thymus Multicellular Organism Growth Regulation Of MRNA Stability Chorio-allantoic Fusion Spongiotrophoblast Layer Development
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Butyrate Response Factor 1 (BRF1) destabilizes mRNA
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088) Prostate cancer ( 23535732)
Protein-protein Interactions		9 interactors: ACD AKT1 MAPK14 MAPKAPK2 PAFAH1B2 POT1 TERF1 TINF2 YWHAB
Entrez ID		677
HPRD ID		03041
Ensembl ID		ENSG00000185650
Uniprot IDs		B3KNA8 Q07352
PDB IDs		1W0V 1W0W
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Replication Telomere Maintenance Positive Regulation Of Transferase Activity Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of DNA Replication Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Organelle Organization Telomere Maintenance Via Telomere Lengthening Regulation Of Organelle Organization Regulation Of DNA Biosynthetic Process Regulation Of Chromosome Organization Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cellular Component Organization Neurotrophin Signaling Pathway Positive Regulation Of Metabolic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Telomerase Activity Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity 3'-UTR-mediated MRNA Stabilization Positive Regulation Of Telomere Maintenance Peptidyl-serine Phosphorylation Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of DNA Metabolic Process Positive Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Negative Regulation Of DNA Biosynthetic Process Cellular Response To Growth Factor Stimulus Regulation Of Protein Metabolic Process MRNA Stabilization Response To Growth Factor Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of MAPK Cascade
Tagcloud ?		antisense ccr4 deadenylase destabilization detailed disruption dissociation erk identifying ldlr lipoprotein oligonucleotide oligonucleotides p90 possibly potency proteomic recruit ribosomal rnas s6 stabilization stabilized therapeutics unstable untranslated usefulness utr