ZFP36L1

Name	ZFP36 ring finger protein like 1
Structure
Novel Interactors	2 novel interactors: CSNK2B PRKCH
Interactors	9 interactors: ACD AKT1 MAPK14 MAPKAPK2 PAFAH1B2 POT1 TERF1 TINF2 YWHAB
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Ribonucleoprotein Complex
	Molecular Function	DNA Binding RNA Binding MRNA Binding Protein Binding Zinc Ion Binding MRNA 3'-UTR AU-rich Region Binding Metal Ion Binding 14-3-3 Protein Binding
	Biological Process	MAPK Cascade Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Vasculogenesis Proepicardium Development MRNA Processing Regulation Of Translation Apoptotic Process Heart Development Cell Population Proliferation Response To Wounding Regulation Of Gene Expression Regulation Of Keratinocyte Proliferation Neural Tube Development Nuclear-transcribed MRNA Catabolic Process, Deadenylation-independent Decay Regulation Of MRNA 3'-end Processing Cellular Response To Insulin Stimulus T Cell Differentiation In Thymus Multicellular Organism Growth P38MAPK Cascade Regulation Of MRNA Stability Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of B Cell Differentiation Positive Regulation Of Fat Cell Differentiation Regulation Of Keratinocyte Differentiation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Monocyte Differentiation Regulation Of Myoblast Differentiation Mesendoderm Development Embryonic Organ Development MRNA Transport Chorio-allantoic Fusion 3'-UTR-mediated MRNA Destabilization ERK1 And ERK2 Cascade Cellular Response To CAMP Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Cellular Response To Peptide Hormone Stimulus Cellular Response To Glucocorticoid Stimulus Cellular Response To Hypoxia Cellular Response To Salt Stress Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Stem Cell Proliferation Cellular Response To Raffinose Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Keratinocyte Apoptotic Process Positive Regulation Of Intracellular MRNA Localization
Pathways	Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
GWAS	Apolipoprotein A1 levels ( 32203549 ) Arthritis (juvenile idiopathic) ( 33106285 ) Asthma ( 31959851 ) Blond vs. brown/black hair color ( 30531825 ) Celiac disease ( 22057235 20190752 25920553 ) Crohn's disease ( 21102463 ) Cutaneous malignant melanoma ( 32341527 ) Diastolic blood pressure ( 30224653 ) Fibrinogen levels ( 26561523 28107422 ) HDL cholesterol levels ( 32203549 ) Hematocrit ( 32888494 ) Hemoglobin ( 32888494 ) Inflammatory bowel disease ( 23128233 ) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761 ) Mean spheric corpuscular volume ( 32888494 ) Metabolite levels ( 23823483 ) Microalbuminuria ( 31511532 ) Multiple sclerosis ( 24076602 21833088 ) Nonsyndromic cleft lip ( 31609978 ) Prostate cancer ( 23535732 ) Rheumatoid arthritis ( 32723749 ) Urinary albumin excretion ( 30220432 ) Urinary albumin-to-creatinine ratio ( 31630189 31511532 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	677
HPRD ID	03041
Ensembl ID	ENSG00000185650
Uniprot IDs	B3KNA8 Q07352
PDB IDs	1W0V 1W0W
GO Terms Enriched among Interactors ?	Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Assembly Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Telomere Maintenance Negative Regulation Of Metabolic Process Negative Regulation Of Chromosome Organization Regulation Of DNA Biosynthetic Process Telomere Maintenance Via Telomerase Telomere Maintenance Positive Regulation Of Chromosome Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of DNA Metabolic Process RNA-templated DNA Biosynthetic Process Regulation Of Telomere Maintenance Cellular Response To Vascular Endothelial Growth Factor Stimulus Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Metabolic Process Telomere Organization Negative Regulation Of DNA Metabolic Process Protein Serine/threonine Kinase Activity Chromosome, Telomeric Region Regulation Of Establishment Of Protein Localization To Telomere Regulation Of DNA Metabolic Process Regulation Of Protein Localization Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Organelle Organization Regulation Of Metabolic Process Regulation Of Chromosome Organization Telomeric D-loop Disassembly RNA Stabilization G-rich Strand Telomeric DNA Binding Telomeric Loop Disassembly Protein Localization To Chromosome, Telomeric Region DNA Biosynthetic Process Negative Regulation Of RNA Catabolic Process Positive Regulation Of Cellular Component Organization Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process