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ZFP36L1 and TINF2
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
ZFP36L1
TINF2
Description
ZFP36 ring finger protein like 1
TERF1 interacting nuclear factor 2
Image
GO Annotations
Cellular Component
P-body
Nucleus
Cytoplasm
Cytosol
Ribonucleoprotein Complex
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Perinucleolar Chromocenter
Nuclear Matrix
Nuclear Body
Shelterin Complex
Molecular Function
DNA Binding
RNA Binding
MRNA Binding
Protein Binding
Zinc Ion Binding
MRNA 3'-UTR AU-rich Region Binding
Metal Ion Binding
14-3-3 Protein Binding
DNA Binding
Protein Binding
Telomeric DNA Binding
Biological Process
MAPK Cascade
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Vasculogenesis
Proepicardium Development
MRNA Processing
Regulation Of Translation
Apoptotic Process
Heart Development
Cell Population Proliferation
Response To Wounding
Regulation Of Gene Expression
Regulation Of Keratinocyte Proliferation
Neural Tube Development
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-independent Decay
Regulation Of MRNA 3'-end Processing
Cellular Response To Insulin Stimulus
T Cell Differentiation In Thymus
Multicellular Organism Growth
P38MAPK Cascade
Regulation Of MRNA Stability
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of B Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Regulation Of Keratinocyte Differentiation
Negative Regulation Of Erythrocyte Differentiation
Positive Regulation Of Monocyte Differentiation
Regulation Of Myoblast Differentiation
Mesendoderm Development
Embryonic Organ Development
MRNA Transport
Chorio-allantoic Fusion
3'-UTR-mediated MRNA Destabilization
ERK1 And ERK2 Cascade
Cellular Response To CAMP
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Stem Cell Proliferation
Cellular Response To Raffinose
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Keratinocyte Apoptotic Process
Positive Regulation Of Intracellular MRNA Localization
Telomere Capping
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomere Lengthening
Pathways
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Diseases
Revesz syndrome; Exudative retinopathy with bone marrow failure
GWAS
Apolipoprotein A1 levels (
32203549
)
Arthritis (juvenile idiopathic) (
33106285
)
Asthma (
31959851
)
Blond vs. brown/black hair color (
30531825
)
Celiac disease (
22057235
20190752
25920553
)
Crohn's disease (
21102463
)
Cutaneous malignant melanoma (
32341527
)
Diastolic blood pressure (
30224653
)
Fibrinogen levels (
26561523
28107422
)
HDL cholesterol levels (
32203549
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Inflammatory bowel disease (
23128233
)
Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) (
23603761
)
Mean spheric corpuscular volume (
32888494
)
Metabolite levels (
23823483
)
Microalbuminuria (
31511532
)
Multiple sclerosis (
24076602
21833088
)
Nonsyndromic cleft lip (
31609978
)
Prostate cancer (
23535732
)
Rheumatoid arthritis (
32723749
)
Urinary albumin excretion (
30220432
)
Urinary albumin-to-creatinine ratio (
31630189
31511532
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Leukocyte telomere length (
31171785
)
Platelet count (
29403010
)
Interacting Genes
9 interacting genes:
ACD
AKT1
MAPK14
MAPKAPK2
PAFAH1B2
POT1
TERF1
TINF2
YWHAB
91 interacting genes:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
ANXA8L1
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CSNK2A1
CTTN
DBN1
DCX
DHFR2
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
MTNR1B
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS1
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TFRC
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
Entrez ID
677
26277
HPRD ID
03041
16056
Ensembl ID
ENSG00000185650
ENSG00000092330
Uniprot IDs
B3KNA8
Q07352
B4DFJ1
Q9BSI4
PDB IDs
1W0V
1W0W
3BQO
3BU8
5XYF
Enriched GO Terms of Interacting Partners
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Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomere Assembly
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Metabolic Process
Negative Regulation Of Chromosome Organization
Regulation Of DNA Biosynthetic Process
Telomere Maintenance Via Telomerase
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of DNA Metabolic Process
RNA-templated DNA Biosynthetic Process
Regulation Of Telomere Maintenance
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Metabolic Process
Telomere Organization
Negative Regulation Of DNA Metabolic Process
Protein Serine/threonine Kinase Activity
Chromosome, Telomeric Region
Regulation Of Establishment Of Protein Localization To Telomere
Regulation Of DNA Metabolic Process
Regulation Of Protein Localization
Regulation Of Establishment Of Protein Localization To Chromosome
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Organelle Organization
Regulation Of Metabolic Process
Regulation Of Chromosome Organization
Telomeric D-loop Disassembly
RNA Stabilization
G-rich Strand Telomeric DNA Binding
Telomeric Loop Disassembly
Protein Localization To Chromosome, Telomeric Region
DNA Biosynthetic Process
Negative Regulation Of RNA Catabolic Process
Positive Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Cytosol
Extracellular Exosome
Cytoplasm
ADP Metabolic Process
Purine Ribonucleotide Catabolic Process
Ribonucleoside Diphosphate Metabolic Process
Glycolytic Process
ADP Catabolic Process
Purine Nucleotide Catabolic Process
Nucleoside Phosphate Catabolic Process
Nucleoside Diphosphate Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Diphosphate Catabolic Process
Cadherin Binding
Pyruvate Metabolic Process
Nucleotide Catabolic Process
Carbohydrate Catabolic Process
Shelterin Complex
Organophosphate Catabolic Process
Glucose Metabolic Process
RNA-templated DNA Biosynthetic Process
Nuclear Telomere Cap Complex
Glucose Catabolic Process
Nucleobase-containing Compound Catabolic Process
Protein Localization To Chromosome, Telomeric Region
ATP Metabolic Process
Hexose Metabolic Process
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Telomere Capping
Nicotinamide Nucleotide Metabolic Process
Purine-containing Compound Metabolic Process
Generation Of Precursor Metabolites And Energy
Ficolin-1-rich Granule Lumen
Nucleobase-containing Small Molecule Metabolic Process
Monosaccharide Metabolic Process
Carbohydrate Derivative Catabolic Process
Phosphoglucomutase Activity
Nucleoside Metabolic Process
Protein Binding
Purine Ribonucleotide Metabolic Process
Calcium-dependent Phospholipid Binding
Cellular Response To Heat
Canonical Glycolysis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Ribonucleotide Metabolic Process
Glycolytic Process Through Glucose-6-phosphate
Glycolytic Process Through Fructose-6-phosphate
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Tagcloud (Intersection)
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