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ZFP36L1 and YWHAB
Number of citations of the paper that reports this interaction (PubMedID
17030608
)
51
Data Source:
BioGRID
(pull down)
ZFP36L1
YWHAB
Description
ZFP36 ring finger protein like 1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
Image
GO Annotations
Cellular Component
P-body
Nucleus
Cytoplasm
Cytosol
Ribonucleoprotein Complex
Nucleus
Cytoplasm
Vacuole
Vacuolar Membrane
Cytosol
Focal Adhesion
Membrane
Transcription Repressor Complex
Protein-containing Complex
Melanosome
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
DNA Binding
RNA Binding
MRNA Binding
Protein Binding
Zinc Ion Binding
MRNA 3'-UTR AU-rich Region Binding
Metal Ion Binding
14-3-3 Protein Binding
Protein Kinase Inhibitor Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
Enzyme Binding
Protein Domain Specific Binding
Identical Protein Binding
Histone Deacetylase Binding
Protein-containing Complex Binding
Cadherin Binding
Phosphoserine Residue Binding
Phosphoprotein Binding
Protein Sequestering Activity
Biological Process
MAPK Cascade
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Vasculogenesis
Proepicardium Development
MRNA Processing
Regulation Of Translation
Apoptotic Process
Heart Development
Cell Population Proliferation
Response To Wounding
Regulation Of Gene Expression
Regulation Of Keratinocyte Proliferation
Neural Tube Development
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-independent Decay
Regulation Of MRNA 3'-end Processing
Cellular Response To Insulin Stimulus
T Cell Differentiation In Thymus
Multicellular Organism Growth
P38MAPK Cascade
Regulation Of MRNA Stability
Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of B Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Regulation Of Keratinocyte Differentiation
Negative Regulation Of Erythrocyte Differentiation
Positive Regulation Of Monocyte Differentiation
Regulation Of Myoblast Differentiation
Mesendoderm Development
Embryonic Organ Development
MRNA Transport
Chorio-allantoic Fusion
3'-UTR-mediated MRNA Destabilization
ERK1 And ERK2 Cascade
Cellular Response To CAMP
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Peptide Hormone Stimulus
Cellular Response To Glucocorticoid Stimulus
Cellular Response To Hypoxia
Cellular Response To Salt Stress
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Stem Cell Proliferation
Cellular Response To Raffinose
Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Keratinocyte Apoptotic Process
Positive Regulation Of Intracellular MRNA Localization
Protein Targeting
Signal Transduction
Intracellular Protein Localization
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
MTOR signalling
mTORC1-mediated signalling
Frs2-mediated activation
Frs2-mediated activation
ARMS-mediated activation
Signaling by Hippo
Rap1 signalling
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
RAF activation
MAP2K and MAPK activation
Negative regulation of MAPK pathway
Signaling by moderate kinase activity BRAF mutants
Signaling by high-kinase activity BRAF mutants
Signaling by BRAF and RAF1 fusions
Paradoxical activation of RAF signaling by kinase inactive BRAF
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
Signaling downstream of RAS mutants
Signaling by RAF1 mutants
SHOC2 M1731 mutant abolishes MRAS complex function
Gain-of-function MRAS complexes activate RAF signaling
SARS-CoV-1 targets host intracellular signalling and regulatory pathways
SARS-CoV-2 targets host intracellular signalling and regulatory pathways
Transcriptional and post-translational regulation of MITF-M expression and activity
Drugs
Copper
Phenethyl Isothiocyanate
Diseases
GWAS
Apolipoprotein A1 levels (
32203549
)
Arthritis (juvenile idiopathic) (
33106285
)
Asthma (
31959851
)
Blond vs. brown/black hair color (
30531825
)
Celiac disease (
22057235
20190752
25920553
)
Crohn's disease (
21102463
)
Cutaneous malignant melanoma (
32341527
)
Diastolic blood pressure (
30224653
)
Fibrinogen levels (
26561523
28107422
)
HDL cholesterol levels (
32203549
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Inflammatory bowel disease (
23128233
)
Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) (
23603761
)
Mean spheric corpuscular volume (
32888494
)
Metabolite levels (
23823483
)
Microalbuminuria (
31511532
)
Multiple sclerosis (
24076602
21833088
)
Nonsyndromic cleft lip (
31609978
)
Prostate cancer (
23535732
)
Rheumatoid arthritis (
32723749
)
Urinary albumin excretion (
30220432
)
Urinary albumin-to-creatinine ratio (
31630189
31511532
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Basophil count (
32888494
)
Basophil percentage of white cells (
32888494
)
Blood protein levels (
30072576
)
Breakfast cereal skipping frequency (
31190057
)
Breakfast skipping (
31190057
)
Mean platelet volume (
32888494
)
Interacting Genes
9 interacting genes:
ACD
AKT1
MAPK14
MAPKAPK2
PAFAH1B2
POT1
TERF1
TINF2
YWHAB
147 interacting genes:
ABL1
ADAM22
AFDN
AKAP13
ALS2
APP
ATP5F1A
BAD
BAX
BCL2L11
BCR
BID
BRAF
C1QBP
CAMK2A
CAMK2B
CBL
CDC25A
CDC25B
CDC25C
CDK11B
CDK14
CDKN1B
CHAF1A
CRTC2
CSNK2A1
DAPK1
DHX15
DYRK1A
EDC3
EGFR
EPB41
EPB41L1
EPB41L3
ERRFI1
EXO1
FER
FILNC1
FRMD6
GAPVD1
GEM
H3C1
HDAC5
HES1
HSP90AB1
HSPA1A
HSPA1B
HSPA5
HSPB1
IGF1R
IKBKB
ING1
INSR
IRS1
IRS2
ITGB1
ITGB4
KANK1
KCNK15
KCNK3
KCNK9
KIAA0930
KIF1C
KIF23
KIF5B
KLC1
KRT18
LARP1
LYST
MAP3K3
MAPK7
MAPT
MARK2
MARK4
MDM4
MICALL1
MINK1
MLXIP
MPRIP
MST1R
MTNR1A
MTNR1B
NCAM2
NEDD4L
OSBPL3
PARD3
PARD6B
PDCL2
PDE3B
PDE4B
PI4KB
PIK3R2
PIK3R4
PRKCD
PRKCG
PRKCZ
PRPF6
PTPN3
RABGEF1
RACGAP1
RADIL
RAF1
RAI14
RALGPS2
RASGRF1
RGS3
RGS7
RIN1
RIOK1
RIPK2
RMDN3
RNPS1
RPS6KA1
SAMSN1
SKP2
SLC4A7
SLC8A1
SLC8A2
SLC8A3
SLC9A1
SNCA
SNRNP200
SON
SRC
SRRM2
SRSF10
SRSF3
STK38
STK38L
TESK1
TESK2
TH
TJP2
TNFAIP3
TPD52L1
TSC1
TSC2
TUBB
UBC
UCP2
UCP3
WDR77
WEE1
YWHAE
YWHAG
ZFP36
ZFP36L1
Entrez ID
677
7529
HPRD ID
03041
03184
Ensembl ID
ENSG00000185650
ENSG00000166913
Uniprot IDs
B3KNA8
Q07352
P31946
V9HWD6
PDB IDs
1W0V
1W0W
2BQ0
2C23
4DNK
5N10
6A5Q
6BYK
6GN0
6GN8
6GNJ
6GNK
6GNN
6HEP
8DP5
8EQ8
8EQH
Enriched GO Terms of Interacting Partners
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Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomere Assembly
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Metabolic Process
Negative Regulation Of Chromosome Organization
Regulation Of DNA Biosynthetic Process
Telomere Maintenance Via Telomerase
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of DNA Metabolic Process
RNA-templated DNA Biosynthetic Process
Regulation Of Telomere Maintenance
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Metabolic Process
Telomere Organization
Negative Regulation Of DNA Metabolic Process
Protein Serine/threonine Kinase Activity
Chromosome, Telomeric Region
Regulation Of Establishment Of Protein Localization To Telomere
Regulation Of DNA Metabolic Process
Regulation Of Protein Localization
Regulation Of Establishment Of Protein Localization To Chromosome
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Organelle Organization
Regulation Of Metabolic Process
Regulation Of Chromosome Organization
Telomeric D-loop Disassembly
RNA Stabilization
G-rich Strand Telomeric DNA Binding
Telomeric Loop Disassembly
Protein Localization To Chromosome, Telomeric Region
DNA Biosynthetic Process
Negative Regulation Of RNA Catabolic Process
Positive Regulation Of Cellular Component Organization
Regulation Of Primary Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Kinase Activity
Protein Kinase Activity
Regulation Of Intracellular Signal Transduction
Intracellular Signal Transduction
Cytosol
Protein Serine Kinase Activity
Regulation Of Cell Communication
Regulation Of Signaling
Protein Serine/threonine Kinase Activity
Regulation Of Signal Transduction
Positive Regulation Of Cell Communication
Cytoplasm
Protein Phosphorylation
ATP Binding
Positive Regulation Of Signaling
Negative Regulation Of Signaling
Negative Regulation Of Cell Communication
Phosphorylation
Negative Regulation Of Signal Transduction
Regulation Of Programmed Cell Death
Regulation Of Apoptotic Process
Positive Regulation Of Intracellular Signal Transduction
Nucleotide Binding
Positive Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Programmed Cell Death
Regulation Of Protein Modification Process
Signal Transduction
Cellular Response To Oxygen-containing Compound
Protein Tyrosine Kinase Activity
Response To Stress
Cellular Response To Stress
Regulation Of Cell Cycle
Regulation Of Membrane Potential
Intracellular Signaling Cassette
Cellular Response To Hormone Stimulus
Cadherin Binding
Regulation Of Protein-containing Complex Assembly
Regulation Of Phosphorus Metabolic Process
Cellular Response To Insulin Stimulus
Regulation Of Protein Phosphorylation
Regulation Of Biological Quality
Plasma Membrane
Response To Insulin
Positive Regulation Of Catabolic Process
Phosphate-containing Compound Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Regulation Of Phosphorylation
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Tagcloud (Intersection)
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