SLC26A6 and PDZK1

Number of citations of the paper that reports this interaction (PubMedID 14531806)
0

Data Source:
HPRD (in vitro, two hybrid)

		SLC26A6	PDZK1
Description		solute carrier family 26 member 6	PDZ domain containing 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Vesicle Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Brush Border Membrane Vesicle Chloride Channel Complex Sperm Midpiece	Plasma Membrane Brush Border Membrane Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Extracellular Exosome
	Molecular Function	Chloride Channel Activity Solute:inorganic Anion Antiporter Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Antiporter Activity Sulfate:bicarbonate Antiporter Activity Formate Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity Transferase Activity Oxalate Transmembrane Transporter Activity PDZ Domain Binding Identical Protein Binding Chloride:bicarbonate Antiporter Activity	Signaling Receptor Binding Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding Transporter Activator Activity
	Biological Process	Monoatomic Ion Transport Chloride Transport Bicarbonate Transport Formate Transport Mannitol Transmembrane Transport Oxalate Transport Transepithelial Chloride Transport Monoatomic Ion Transmembrane Transport Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Estrous Cycle Oxalic Acid Secretion Sperm Capacitation Intestinal Absorption Regulation Of Intracellular PH Intracellular PH Elevation Establishment Of Localization In Cell Transmembrane Transport Protein Kinase C Signaling Transepithelial Transport Cellular Response To CAMP Cellular Response To Fructose Stimulus Cellular Response To Type II Interferon Sulfate Transmembrane Transport Chloride Transmembrane Transport Positive Regulation Of Dipeptide Transmembrane Transport	Regulation Of Monoatomic Anion Transport Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Carnitine Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Inorganic anion exchange by SLC26 transporters
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Contrast sensitivity ( 24152035) Gout ( 32238385 33832965) Serum uric acid levels ( 30993211) Urate levels ( 20884846 23263486 31578528 31985003) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)
Interacting Genes		12 interacting genes: APOL2 AQP2 BET1 CD81 ERG28 LAT PDZK1 PLP1 SNORC TF TMEM128 TMEM201	30 interacting genes: ABCA1 ABCC2 ABCC4 ACE2 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP NHERF2 PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC13A1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLCO1A2 SLK SSTR5 UBE2I
Entrez ID		65010	5174
HPRD ID		10235	04829
Ensembl ID		ENSG00000225697	ENSG00000174827
Uniprot IDs		A0A0C4DFT5 G3XAC1 Q96MZ1 Q9BXS9	B2R7S7 Q5T2W1
PDB IDs		8OPQ	2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI
Enriched GO Terms of Interacting Partners?		Membrane Transferrin Receptor Binding	Apical Plasma Membrane Transmembrane Transport PDZ Domain Binding Monoatomic Ion Transport Organic Anion Transport Transmembrane Transporter Activity Brush Border Membrane Plasma Membrane Inorganic Anion Transport Organic Hydroxy Compound Transport Carboxylic Acid Transport Organic Acid Transport Xenobiotic Transport Symporter Activity Inorganic Anion Transmembrane Transport Monoatomic Anion Transmembrane Transport Monoatomic Anion Transport Membrane Urate Transport Monoatomic Ion Transmembrane Transport Urate Metabolic Process ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Sodium Ion Transport ABC-type Transporter Activity Lipid Transport Cell Surface Xenobiotic Export From Cell Monocarboxylic Acid Transport Apolipoprotein Binding Export Across Plasma Membrane Organic Anion Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Basal Plasma Membrane Import Across Plasma Membrane Vascular Process In Circulatory System Bile Acid And Bile Salt Transport Xenobiotic Transmembrane Transporter Activity Amino-acid Betaine Transmembrane Transporter Activity Chemical Homeostasis Transport Across Blood-brain Barrier Regulation Of Intracellular PH Organic Cation Transport Regulation Of Cellular PH Circulatory System Process Inorganic Ion Transmembrane Transport Carnitine Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity Antiporter Activity Peptide Transport Regulation Of PH
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