PDZK1 and PDZK1IP1

Number of citations of the paper that reports this interaction (PMID 9461128)
33

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		PDZK1	PDZK1IP1
Gene Name		PDZ domain containing 1	PDZK1 interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Vesicular Exosome	Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Scavenger Receptor Binding Transporter Activity Protein Binding PDZ Domain Binding Protein Complex Binding
	Biological Process	Transport Cell Proliferation Carnitine Transport Drug Transport Positive Regulation Of Ion Transmembrane Transport Regulation Of Anion Transport Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane
Pathways
Drugs
Diseases
GWAS		Urate levels ( 20884846 23263486) Uric acid levels ( 19503597)
Protein-Protein Interactions		27 interactors: ABCA1 ABCC2 ABCC4 AKAP10 APP CFTR CLCN3 FARP2 GFAP PDZK1IP1 PEX5 SCARB1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A3 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	4 interactors: COPS6 PDZK1 UTP14A ZDHHC17
Entrez ID		5174	10158
HPRD ID		04829	06211
Ensembl ID		ENSG00000174827	ENSG00000162366
Uniprot IDs		Q5T2W1	Q13113
PDB IDs		2EEI 2EEJ 2VSP 3TMH
Enriched GO Terms of Interacting Partners?		Anion Transport Transmembrane Transport Anion Transmembrane Transport Organic Anion Transport Ion Transport Ion Transmembrane Transport Homeostatic Process Chemical Homeostasis Ion Homeostasis Monocarboxylic Acid Transport Inorganic Anion Transport Transport Organic Acid Transport Anion Homeostasis Urate Metabolic Process Sodium Ion Transport Cellular Ion Homeostasis Cellular Homeostasis Lipid Transport Regulation Of PH Carboxylic Acid Transport Response To Drug Cellular Chemical Homeostasis Lipid Localization Monovalent Inorganic Cation Transport Antibiotic Transport Steroid Metabolic Process Cholesterol Metabolic Process Regulation Of Intracellular PH Regulation Of Cellular PH Sterol Metabolic Process Drug Transport Cellular Phosphate Ion Homeostasis Intracellular PH Elevation Cell Maturation Sodium-dependent Phosphate Transport Transepithelial Chloride Transport Neuron Remodeling Secretion Cholesterol Transport Sterol Transport Oligopeptide Transport Carnitine Transmembrane Transport Carnitine Transport Small Molecule Metabolic Process Transepithelial Transport Phosphate Ion Homeostasis Phosphate Ion Transmembrane Transport Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Peptide Transport	Cullin Deneddylation Protein Deneddylation Carnitine Transport Quaternary Ammonium Group Transport Lipoprotein Transport Magnesium Ion Transport
Tagcloud ?		across agr2 assigned differently effector endocrine ergs estradiol exploitable greb1 interpretation menstrual mirroring pgr premenopausal progesterone rankl responsiveness rhythm runx1 serpina3 serpina5 tff1 tumours varies w1 w2 w3 windows	appreciated chip combinations critically depends enhancer enriched erythroid fli1 gata1 gata2 hematopoiesis hematopoietic lineages megakaryocytes multifactor offers perturbation powerful regulators runx1 screen seq shared simultaneous tal1 thrombocyte throughput zebrafish
Tagcloud (Difference) ?		across agr2 assigned differently effector endocrine ergs estradiol exploitable greb1 interpretation menstrual mirroring pgr premenopausal progesterone rankl responsiveness rhythm serpina3 serpina5 tff1 tumours varies w1 w2 w3 windows	appreciated chip combinations critically depends enhancer enriched erythroid fli1 gata1 gata2 hematopoiesis hematopoietic lineages megakaryocytes multifactor offers perturbation powerful regulators screen seq shared simultaneous tal1 thrombocyte throughput zebrafish
Tagcloud (Intersection) ?		runx1