PDZK1 and SLC15A2

Number of citations of the paper that reports this interaction (PMID 15553237)
5

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PDZK1	SLC15A2
Gene Name		PDZ domain containing 1	solute carrier family 15 (oligopeptide transporter), member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Scavenger Receptor Binding Transporter Activity Protein Binding PDZ Domain Binding Protein Complex Binding	Protein Binding Peptide:proton Symporter Activity High-affinity Oligopeptide Transporter Activity Antibiotic Transporter Activity Dipeptide Transporter Activity
	Biological Process	Transport Cell Proliferation Carnitine Transport Drug Transport Positive Regulation Of Ion Transmembrane Transport Regulation Of Anion Transport Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane	Transport Ion Transport Protein Transport Drug Transport Proton Transport Antibiotic Transport Dipeptide Transport Transmembrane Transport
Pathways			Transport of inorganic cations/anions and amino acids/oligopeptides Proton/oligonucleotide cotransporters SLC-mediated transmembrane transport
Drugs
Diseases
GWAS		Urate levels ( 20884846 23263486) Uric acid levels ( 19503597)	Multiple sclerosis ( 21833088)
Protein-Protein Interactions		27 interactors: ABCA1 ABCC2 ABCC4 AKAP10 APP CFTR CLCN3 FARP2 GFAP PDZK1IP1 PEX5 SCARB1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A3 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	2 interactors: PDZD3 PDZK1
Entrez ID		5174	6565
HPRD ID		04829	09088
Ensembl ID		ENSG00000174827	ENSG00000163406
Uniprot IDs		Q5T2W1	Q16348
PDB IDs		2EEI 2EEJ 2VSP 3TMH
Enriched GO Terms of Interacting Partners?		Anion Transport Transmembrane Transport Anion Transmembrane Transport Organic Anion Transport Ion Transport Ion Transmembrane Transport Homeostatic Process Chemical Homeostasis Ion Homeostasis Monocarboxylic Acid Transport Inorganic Anion Transport Transport Organic Acid Transport Anion Homeostasis Urate Metabolic Process Sodium Ion Transport Cellular Ion Homeostasis Cellular Homeostasis Lipid Transport Regulation Of PH Carboxylic Acid Transport Response To Drug Cellular Chemical Homeostasis Lipid Localization Monovalent Inorganic Cation Transport Antibiotic Transport Steroid Metabolic Process Cholesterol Metabolic Process Regulation Of Intracellular PH Regulation Of Cellular PH Sterol Metabolic Process Drug Transport Cellular Phosphate Ion Homeostasis Intracellular PH Elevation Cell Maturation Sodium-dependent Phosphate Transport Transepithelial Chloride Transport Neuron Remodeling Secretion Cholesterol Transport Sterol Transport Oligopeptide Transport Carnitine Transmembrane Transport Carnitine Transport Small Molecule Metabolic Process Transepithelial Transport Phosphate Ion Homeostasis Phosphate Ion Transmembrane Transport Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Peptide Transport	Negative Regulation Of CGMP Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity CGMP-mediated Signaling Receptor Guanylyl Cyclase Signaling Pathway Carnitine Transport Quaternary Ammonium Group Transport Regulation Of CGMP Biosynthetic Process Negative Regulation Of Lyase Activity Cyclic-nucleotide-mediated Signaling Regulation Of CGMP Metabolic Process Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of Nucleotide Metabolic Process Water Transport Drug Transport Fluid Transport Regulation Of Cyclase Activity Ion Transport Ammonium Transport Positive Regulation Of Ion Transmembrane Transport Establishment Of Protein Localization To Plasma Membrane Monocarboxylic Acid Transport Regulation Of Anion Transport Second-messenger-mediated Signaling Protein Localization To Plasma Membrane Positive Regulation Of Intracellular Protein Transport Response To Toxic Substance Positive Regulation Of Ion Transport Plasma Membrane Organization Establishment Of Protein Localization To Membrane Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Inorganic Anion Transport
Tagcloud ?		across agr2 assigned differently effector endocrine ergs estradiol exploitable greb1 interpretation menstrual mirroring pgr premenopausal progesterone rankl responsiveness rhythm runx1 serpina3 serpina5 tff1 tumours varies w1 w2 w3 windows	abcb11 abcg5 abcg8 acetylated bisulfite bsep cerebrum cpg cpgs dinucleotides g8 hyperacetylated hypermethylated hypomethylated kidney methylated ntcp oatp1b2 opposite pept2 profiling start tag tightly transporters tss underlies
Tagcloud (Difference) ?		across agr2 assigned differently effector endocrine ergs estradiol exploitable greb1 interpretation menstrual mirroring pgr premenopausal progesterone rankl responsiveness rhythm runx1 serpina3 serpina5 tff1 tumours varies w1 w2 w3 windows	abcb11 abcg5 abcg8 acetylated bisulfite bsep cerebrum cpg cpgs dinucleotides g8 hyperacetylated hypermethylated hypomethylated kidney methylated ntcp oatp1b2 opposite pept2 profiling start tag tightly transporters tss underlies
Tagcloud (Intersection) ?