SLC26A6 and ERG28

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC26A6	ERG28
Description		solute carrier family 26 member 6	ergosterol biosynthesis 28 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Cytosol Plasma Membrane Vesicle Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Brush Border Membrane Vesicle Chloride Channel Complex Sperm Midpiece	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Transport Vesicle
	Molecular Function	Chloride Channel Activity Solute:inorganic Anion Antiporter Activity Protein Binding Secondary Active Sulfate Transmembrane Transporter Activity Bicarbonate Transmembrane Transporter Activity Chloride Transmembrane Transporter Activity Sulfate Transmembrane Transporter Activity Antiporter Activity Sulfate:bicarbonate Antiporter Activity Formate Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity Transferase Activity Oxalate Transmembrane Transporter Activity PDZ Domain Binding Identical Protein Binding Chloride:bicarbonate Antiporter Activity	Protein Binding Protein-macromolecule Adaptor Activity Identical Protein Binding
	Biological Process	Monoatomic Ion Transport Chloride Transport Bicarbonate Transport Formate Transport Mannitol Transmembrane Transport Oxalate Transport Transepithelial Chloride Transport Monoatomic Ion Transmembrane Transport Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Estrous Cycle Oxalic Acid Secretion Sperm Capacitation Intestinal Absorption Regulation Of Intracellular PH Intracellular PH Elevation Establishment Of Localization In Cell Transmembrane Transport Protein Kinase C Signaling Transepithelial Transport Cellular Response To CAMP Cellular Response To Fructose Stimulus Cellular Response To Type II Interferon Sulfate Transmembrane Transport Chloride Transmembrane Transport Positive Regulation Of Dipeptide Transmembrane Transport	Lipid Metabolic Process Steroid Biosynthetic Process Steroid Metabolic Process Sterol Biosynthetic Process
Pathways		Inorganic anion exchange by SLC26 transporters
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		12 interacting genes: APOL2 AQP2 BET1 CD81 ERG28 LAT PDZK1 PLP1 SNORC TF TMEM128 TMEM201	127 interacting genes: ALDH2 ANXA1 ANXA7 AQP2 AQP3 AQP6 ARL13B BAIAP2 BCL2L13 BID BTBD2 CCDC106 CCL18 CD53 CD74 CDC42 CDK5RAP2 CELF3 CLDN5 CLDN7 CLN8 COX17 COXFA4L2 CRADD CREB1 CREB3 CREB3L1 CSTF2 CYB561 DYNLL1 EBP ELOVL4 ERBB2 ERBB3 ERBB4 ERGIC3 FAM174A FAM209A FAS FCGR2B FFAR2 FXR1 FXYD3 GADD45A GET1 GJB5 GPR152 GPR37L1 GPR42 GPX8 GSK3B HMGB1 HNRNPH3 HNRNPUL1 HSD17B11 HSPE1 HTR2C HYLS1 JAGN1 KCNJ6 KLHL20 LHFPL5 LMNA LSM2 LYPD5 MAPK8IP2 MGST3 MPHOSPH6 MRM1 MRPL38 MRPS12 MS4A3 MSMO1 MTERF3 MTNR1B MUC1 NAT9 NCR3LG1 NDUFA3 NR1H2 NSDHL NSF PAFAH1B3 PCDHA4 PDZK1IP1 PEX2 PFN1 PHYHIP PIGY POLE2 POLR2C POLR3F PPP1R8 PQBP1 PSCA RAB27A REEP4 RETREG3 RPS6KA6 S100A8 SAR1A SAT1 SEPHS1 SERPINB9 SGPL1 SLC10A6 SLC26A6 SLC34A2 SLC71A2 SNRPB SNRPG SSMEM1 STOM STX1A SULT1E1 TFG TK1 TLCD4 TM4SF19 TMEM106A TMEM222 TMEM31 TMPRSS2 TSC22D1 TTR ZFP64 ZNF24
Entrez ID		65010	11161
HPRD ID		10235	05201
Ensembl ID		ENSG00000225697	ENSG00000133935
Uniprot IDs		A0A0C4DFT5 G3XAC1 Q96MZ1 Q9BXS9	Q6FII3 Q86TW5 Q9UKR5
PDB IDs		8OPQ
Enriched GO Terms of Interacting Partners?		Membrane Transferrin Receptor Binding	Protein Binding Membrane Identical Protein Binding Negative Regulation Of Apoptotic Process Renal Water Transport Negative Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway Polyol Transmembrane Transport Regulation Of Apoptotic Process Positive Regulation Of Cardiac Muscle Tissue Development ERBB3:ERBB2 Complex Regulation Of Secretion Regulation Of Programmed Cell Death Endoplasmic Reticulum Membrane Regulation Of MAPK Cascade Fluid Transport Water Channel Activity Positive Regulation Of MAPK Cascade Positive Regulation Of Viral Entry Into Host Cell Neuregulin Receptor Activity Regulation Of Transport Negative Regulation Of Hemopoiesis Negative Regulation Of Secretion Apolipoprotein A-I Receptor Binding Regulation Of Protein-containing Complex Assembly Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Peptide Secretion Apical Plasma Membrane Positive Regulation Of Transport
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