GIP and GIPR

Number of citations of the paper that reports this interaction (PMID 8795084)
6

Data Source:
HPRD (in vivo)

		GIP	GIPR
Gene Name		gastric inhibitory polypeptide	gastric inhibitory polypeptide receptor
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Secretory Granule Lumen Neuronal Cell Body	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Hormone Activity	Transmembrane Signaling Receptor Activity Gastric Inhibitory Peptide Receptor Activity Peptide Hormone Binding
	Biological Process	Signal Transduction Female Pregnancy Memory Adult Locomotory Behavior Response To Glucose Response To Selenium Ion Positive Regulation Of Glucose Transport Response To Organic Cyclic Compound Sensory Perception Of Pain Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Response To Lipid Exploration Behavior Response To Drug Response To Starvation Response To Amino Acid Response To Peptide Hormone Positive Regulation Of CAMP-mediated Signaling Cellular Protein Metabolic Process Response To Axon Injury Regulation Of Insulin Secretion Digestive System Development Long-term Synaptic Potentiation Positive Regulation Of Glucagon Secretion Triglyceride Homeostasis	Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Generation Of Precursor Metabolites And Energy Cell Surface Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nutrient Response To Glucose Endocrine Pancreas Development Positive Regulation Of Insulin Secretion Gastric Inhibitory Peptide Signaling Pathway Response To Axon Injury Response To Calcium Ion Response To Fatty Acid
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR G alpha (s) signalling events Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Glucagon-type ligand receptors GPCR ligand binding Metabolic disorders of biological oxidation enzymes Peptide hormone metabolism GPCR downstream signaling Class B/2 (Secretin family receptors) Incretin synthesis, secretion, and inactivation	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Glucagon-type ligand receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Coronary heart disease ( 21378990)	Body mass index ( 22344219 22344221 20935630) Obesity ( 23563607) Subcutaneous adipose tissue ( 22589738) Two-hour glucose challenge ( 20081857)
Protein-Protein Interactions		5 interactors: ADAMTSL4 GIPR KRTAP10-3 NOTCH2NL SGTA	2 interactors: GIP LNX1
Entrez ID		2695	2696
HPRD ID		15925	00670
Ensembl ID		ENSG00000159224	ENSG00000010310
Uniprot IDs		P09681	B7WP14 P48546
PDB IDs		1T5Q 2B4N 2L70 2L71 2OBU 2QKH	2QKH 4HJ0
Enriched GO Terms of Interacting Partners?		Gastric Inhibitory Peptide Signaling Pathway	Positive Regulation Of Glucagon Secretion Response To Selenium Ion Regulation Of Glucagon Secretion Positive Regulation Of CAMP-mediated Signaling Regulation Of CAMP-mediated Signaling Exploration Behavior Triglyceride Homeostasis Acylglycerol Homeostasis
Tagcloud ?		32pua aspirated aspiration corp curved cystadenomas cytologic eum eus fg gauge grassau medizin melville negatives ny olympus orangeburg passes pentax pseudocyst resolving rtfna rtfnas staging suspicious technik tomographic unsuccessful	3t3 adipocyte adipocytes antiapoptosis attributable biology car chemokines circulating consequence cytokines exerts ikb ikkbeta impaired insulinotropic jnk jun knockout l1 obese obesity overexpressed pka rising secretion stimulated uptake
Tagcloud (Difference) ?		32pua aspirated aspiration corp curved cystadenomas cytologic eum eus fg gauge grassau medizin melville negatives ny olympus orangeburg passes pentax pseudocyst resolving rtfna rtfnas staging suspicious technik tomographic unsuccessful	3t3 adipocyte adipocytes antiapoptosis attributable biology car chemokines circulating consequence cytokines exerts ikb ikkbeta impaired insulinotropic jnk jun knockout l1 obese obesity overexpressed pka rising secretion stimulated uptake
Tagcloud (Intersection) ?